protein interactions
Protein-protein interactions
... on protein surfaces, for the subsequent automatic construction of novel ligands to fit specific binding ...dimeric protein (inorganic pyrophosphatase), to predict the position of the dimer ...of ...
221
Protein coadaptation and the design of novel approaches to identify protein protein interactions
... novel protein–protein interactions that are vital for the cell and the organism ...abundant interactions among nervous system CSS described to date, however, there is a vast number of orphan ...
8
The interactome: Predicting the protein-protein interactions in cells
... of interactions that also contain the stable protein complexes ...on protein sequences, structures and their interactions are available ...confirmed protein-protein pairings ...
22
Protein interactions during coronavirus assembly.
... identify protein-protein interactions by using the bovine coronavirus (BCV) as the prototype for the coronavirus strains that express ...the protein (for review, see reference ...S ...
7
Extracting Protein-Protein Interactions with Language Modelling
... In this paper we have presented and experimented several systems, that can be easily implemented, to extract directed Protein-Protein Interactions in bio-medical texts. We have shown that modeling ...
7
A bayesian kernel for the prediction of protein-protein interactions
... a protein in order to understand its ...predict protein-protein ...predict protein-protein ...experimental protein-protein interactions data that were compiled from ...
6
Interface residues of transient protein-protein complexes have extensive intra-protein interactions apart from inter-protein interactions
... transient protein-protein binary inter- faces using in-house ...intra-protein interactions than inter-protein interactions in general, though the later can be equal to or even ...
14
Computational Design Of Protein–ligand And Protein–protein Interactions
... recognition. Protein–ligand and protein–protein interactions make up the bulk of the chemical processes that give rise to living ...of protein design technology will therefore require ...
196
Strategies and Functional Consequences of Inhibiting Protein-Protein Interactions.
... how protein networks change in response to chemical inhibitors, three considerations are important: 1) what are the PPIs that converge on the target protein?, 2) what conformation of the target is captured ...
171
In silico prediction of protein protein interactions in human macrophages
... tissue-specific interactions; similarly, Rachlin and colleagues [27] provided networks dedicated to particular biological processes by con- textualizing them with Gene Ontology ...expression, protein ...
11
DAPPER: a data-mining resource for protein-protein interactions
... DAPPER is content-rich and carefully curated with high-resolution experiments per- formed using affinity purifications followed by mass spectrometry. DAPPER is pre- sented through widely accepted and interoperable web ...
8
Motif mediated protein-protein interactions as drug targets
... Protein-protein interactions (PPI) are involved in virtually every cellular process and thus represent an attractive target for therapeutic ...of protein interactions are frequently ...
12
Geminivirus C3 Protein: Replication Enhancement and Protein Interactions
... C3 protein interac- tions are likely to be difficult to abolish by site-directed muta- tion because of the involvement of multiple contacts and non- specific stabilization by residues outside of the binding site ...
11
Prediction of obligate and non-obligate protein-protein interactions
... of interactions that happen within the protein complex or between different protein ...complexes. Protein-protein interaction may change the shape of the complex or modify another ...
90
The multiple roles of histidine in protein interactions
... in protein interactions, often the key residue in enzyme catalytic ...π interactions, in which the histidine acts as the aromatic π -motif in neutral form (His), or plays the cation role in ...
12
Protein Interactions on Telomeric Retrotransposons in Drosophila
... new protein components of the HTT array: Chromator (Chro), the TRF2/DREF complex and the sumoylation ...The protein interactions controlling HTT chromatin structure and telomere length may be ...
7
Protein-protein interactions in an alphavirus membrane.
... To further define protein interactions in the Sindbis virus membrane, we investigated the stability of the oligomers by exposing the virus to progressively increasing concentrations of T[r] ...
8
SIGNET: A Neural Network Architecture for Predicting Protein-Protein Interactions
... of protein-protein interactions (PPI) is critically important within the field of Molecular Biology, as proteins facilitate key organismal functions including the main- tenance of both cellular ...
84
The regulation of CFTR by protein-protein interactions
... disrupt protein interactions in Calu-3 cells and further showed that PKAII is targeted to the plasma membrane by association with A-kinase anchoring proteins (AKAPs) (Huang et ...cytoskeletal-associated ...
191
Multi way Relation Classification: Application to Protein Protein Interactions
... In the BioNLP literature there have recently been a number of attempts to automatically extract protein-protein interactions from PubMed abstracts. Some approaches simply report that a relation ...
8