Protein Sorting
Yeast Mn2+ Transporter, Smf1p, Is Regulated by Ubiquitin-Dependent Vacuolar Protein Sorting
... late secretory pathway to the biosynthetic route of the kinetics (Babst et al. 2002). Interestingly, class E mu- vacuolar protein sorting pathway (Helliwell et al. tants vps4⌬, vps2⌬, and vps24⌬, along with ...
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Vacuolar Protein Sorting Pathway Contributes to the Release of Marburg Virus
... dosomal sorting complexes required for transport (ESCRTs), which mainly constitute the vacuolar protein sorting (VPS) pathway (16, 38, 42, ...
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Lipid and Protein Sorting by, and Generation of, Membrane Curvature in Model Systems
... the sorting of both lipids and proteins between membranes of different organelles within the cell, each with distinct lipid and protein ...and protein sorting. In addition, lipid and ...
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The Structure of a Transmembrane Protein Sorting Complex
... Figure A.5. Members of the Get3/ArsA fold family. (A) Cartoon representations of dimers of members of the ArsA fold viewed down the putative TA binding groove. The structures are the transition state S. cerevisiae Get3 ...
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The Endosomal Protein-Sorting Receptor Sortilin Has a Role in Trafficking α-1 Antitrypsin
... vacuolar sorting of a soluble, misfolded, heterologous protein, and it was hypothesized that Vps10 might be able to nonspecifically bind to extended polypeptides that result from partial misfolding (Hong et ...
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Vacuolar Protein Sorting Protein 13A, TtVPS13A, Localizes to the Tetrahymena thermophila Phagosome Membrane and Is Required for Efficient Phagocytosis
... There are currently few molecular markers in Tetrahymena that allow the various stages of phagolysosome biogenesis to be distinguished. However, we were able to monitor both phago- some acidification, using LysoTracker ...
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Endosymbiont or host: who drove mitochondrial and plastid evolution?
... first protein component to be “tinkered” with probably was the OM channel Tom40 because protein sorting to inside the organelle requires that host proteins could first cross an open gate in the ...
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Endosomal trafficking of yeast membrane proteins
... cargo sorting through the endosomal system have been elucidated in ...vacuolar protein sorting and autophagy pathways, all of which impinge on the endosomal ...vacuolar protein sorting ...
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Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5
... protein sorting. Be- cause beclin 1 functions in both autophagy and protein sorting, it represents an intriguing therapeutic target for neurodegenerative ...enhanced protein ...
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Dysregulation of protein trafficking in neurodegeneration
... of protein trafficking in the context of neurodegenerative diseases is far from ...in protein sorting and neuropathology found in DS and AD so far, further studies are anticipated to uncover unique ...
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GPI biosynthesis is essential for rhodopsin sorting at the trans Golgi network in Drosophila photoreceptors
... resistant membrane (DRM). Lipid rafts, which are normally isolated as DRM, are believed to play an important role in protein sorting at the TGN or the recycling endosomes of polarized epithelial cells ...
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Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis
... Vacuolar protein sorting protein 33b (VPS33B) mutations have been initially identified as the main causes for arthrogryposis, renal dysfunction, and cholestasis (ARC) syndrome, which is an autosomal ...
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Candida albicans VPS11 Is Required for Vacuole Biogenesis and Germ Tube Formation
... (vacuolar protein sorting) mutants of Saccharomyces cerevisiae are defective in multiple protein delivery pathways to the vacuole and prevacuole ...
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Enhancement of Murine Coronavirus Replication by Severe Acute Respiratory Syndrome Coronavirus Protein 6 Requires the N-Terminal Hydrophobic Region but Not C-Terminal Sorting Motifs
... such protein, encoded by ORF6, enhanced the growth of mouse hepatitis virus in tissue culture cells and in ...mice. Protein 6 consists of an N-terminal hydrophobic peptide and a C-terminal region containing ...
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Pth1/Vam3p Is the Syntaxin Homolog at the Vacuolar Membrane of Saccharomyces cerevisae Required for the Delivery of Vacuolar Hydrolases
... olar protein-sorting pathway, the other being Vps45p, which functions at the Golgi-to-endosome ...lase sorting and processing and also results in a vestigial vacuole phenotype ( Jones 1977; Banta et ...
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View pdf
... computing. Sorting problem and algorithms were known for quite some ...oldest sorting algorithm is that of the Hollerith sorter ...many sorting algorithms with some being more appropriate for certain ...
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Is There an Oblivious RAM Lower Bound?
... Damg˚ ard, Medlegard, and Nielsen [DMN11] proved a lower bound on the amount of secret randomness required for a probabilistic RAM to obliviously simulate an arbitrary RAM in an online setting. Namely, if fewer than n/8 ...
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Educational Alternatives, Volume 16, 2018
... automated sorting of mail. In terms of letter sorting machines, it was implemented two models, the first model was the CRS lines (Figure 4), and the FSM model ...
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Structural Insights into Tail-Anchored Protein Targeting by Get3
... TA is in the chamber the soluble domain extends out through the gap in the cage. The consequence would be that Get3 would only protect a minimal amount of the TA protein from solvent. Our double affinity tagged ...
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A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis
... cell sorting (FACS) analysis (A), mouse astrocytes identified by glial fibrillary acidic protein (GFAP) were examined for extracellular matrix metalloproteinase inducer (EMMPRIN) expression using hybridoma ...
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