Purkinje Neurons
Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons
... P12 Purkinje neurons, where blockade of the SK channels by apamin favored the occurrence of spontaneous bursting and the transition from a silent to a spiking behavior ...adult Purkinje ...
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Synaptic integration and dendritic excitability in cerebellar Purkinje neurons
... pyramidal neurons there is a roughly constant overall density of calcium channels along the apical dendrite (Magee 1999); however, the density of L-type channels is higher proximally, while T-type channels are ...
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Does Intake of Ethanol and Khat (Catha Edulis Forsk) Affect the Total Number of Purkinje Neurons in Early Postnatal Rats?
... of neurons was estimated by the dissector ...method, neurons to be counted are those that appear in the reference section and not on the look-up ...Then, neurons within the grid and those intercepted ...
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Mathematical model of bursting in dissociated Purkinje neurons
... full Purkinje cell morphology, its inherent trimodal (or tonic) firing pattern can be eventually replaced with a phase of bursting and then a depolarisation block ...isolated Purkinje somata ...
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Caspase mediated apoptosis induction in zebrafish cerebellar Purkinje neurons
... crossed with carriers of the Tg(gata1:egfp) strain marking granule cells by green fluorescence (B,C) or with Tg(olig2:egfp) carriers displaying green fluorescent eurydendroid cells (D). Double transgenic 4 dpf larvae ...
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Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice
... cerebellar development, and increasing evidence suggests that both oligodendrocyte precursor cells and oligoden- drocytes can contribute to neuroinflammation and disease progression in many diseases [58 – 61], very ...
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Purkinje neuron specific down regulation of p38 protects motoric function from the repeated use of benzodiazepine
... containing Purkinje layers that showed a clear image across all treatment ...in Purkinje neurons along the Purkinje layer, and they more distinctively appeared in BZD-injected mice than ...
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Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster
... not: Purkinje neurons may not express the α1 isoform [99]. Purkinje neurons are particu- larly rich in the α3 Na + /K + pump isoform and Carbon Monoxide (CO) gas, which is likely an endogenous ...
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Ocasio_unc_0153D_18979.pdf
... Proliferation must be precisely controlled during brain development. Insufficient proliferation causes microcephaly while excessive proliferation causes tumorigenesis (Ten Donkelaar and Lammens, 2009; Bosemani and ...
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Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death
... of Purkinje cell degeneration have implicated the autophagy pathway in the dysfunction and death of Purkinje ...cerebellar Purkinje cell death, as mutant GRID2 can activate beclin- 1/Atg6 via an ...
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Index Catalog // Carolina Digital Repository
... the Purkinje cell layer ...that Purkinje soma/AIS-localized Nfasc is required for terminating basket axon extension and forming stable contacts at the Purkinje ...the Purkinje soma ...the ...
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Brain Neurotransmitters and Neuromodulators in Pediatrics
... GABA, the most prevalent inhibitory neurotransmitter in the brain, is located in stellate neurons within all layers of the. cortex as well as in cerebellar Purkinje neurons.#{176}’9’[r] ...
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Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse
... the Purkinje cell layer, (2) the somata were elliptical in shape and emitted large-diameter processes from both poles in the sagittal plane, and (3) these processes were primarily confined throughout their course ...
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Xenografting of human umbilical mesenchymal stem cells from Wharton’s jelly ameliorates mouse spinocerebellar ataxia type 1
... of Purkinje cells in the cerebellum also declined in these two ...of Purkinje cell in the unit length of Purkinje cell layer in the Lobules III or VI was shown for the quantification of the number of ...
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PCP4 regulates Purkinje cell excitability and cardiac rhythmicity
... Cardiac Purkinje cells are important triggers of ventricular arrhythmias associated with heritable and acquired syndromes; however, the mechanisms responsible for this proarrhythmic behavior are incompletely ...of ...
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Anatomically Realistic Structural Modeling of the Cardiac Purkinje Network: A Basis for Studying Contributions of the Conduction System to Ventricular Arrhythmias
... Realistic Purkinje Networks In applying our texture-mapping technique to produce three-dimensional Purkinje networks, our goal was to produce anatomically realistic struc- ...the Purkinje network ...
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Nkx2 5 mutation causes anatomic hypoplasia of the cardiac conduction system
... Standard clinical electrophysiological pacing protocols were used to determine all basic electrophysiological parameters (16–18). The AV-His-Purkinje conduction properties were assessed by rapid atrial pacing at ...
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Synaptic inhibition of cerebellar Purkinje cells
... and Purkinje cells is less ...the Purkinje cell somata to the outermost border o f the cerebellar cortex; therefore, these recordings probably included both basket cells and stellate ...
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Sørensen, Jonna (2007): Untersuchungen zur Funktion von Thioredoxin Reduktase 1 in der ZNS-Entwicklung in konditionalen Knockout-Mäusen. Dissertation, LMU München: Tierärztliche Fakultät
... Retardation der Fissuren-Bildung sichtbar und setzt sich in der postnatalen Kleinhirn- Entwicklung fort. Die Knockout-Tiere bleiben in der Gewichtsentwicklung hinter den Kontroll-Tieren zurück und weisen eine massive ...
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His Purkinje conduction during retrograde stress
... The pattern of retrograde His-Purkinje conduction was evaluated in 28 patients using ventricular extrastimuli. In each patient progressive prolongations of His-Purkinje conduction (S2H2) which appeared as ...
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