quantitative trait locus
Identification of a major quantitative trait locus underlying salt tolerance in ‘Jidou 12’ soybean cultivar
... of the genomic location and genetic effect of the major quantitative trait locus (QTL), which conditions salt tol- erance in soybean. Two QTLs associated with salt tol- erance have been mapped on ...
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Mapping of a quantitative trait locus for blood pressure on rat chromosome 2
... A genetic map for rat chromosome 2 that includes five candidate genes for blood pressure regulation was constructed in a region containing a quantitative trait locus (QTL) for blood pressure. Two F2 ...
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Characterizing the Saltol quantitative trait locus for salinity tolerance in rice
... Septiningsih et al. 2009), the Saltol locus will likely be just one component of a multifaceted strategy to improve rice yields on salt affected soils. The initial steps have been taken to use two donors for the ...
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Multilevel-analysis identify a cis -expression quantitative trait locus associated with risk of renal cell carcinoma
... The locus, which was also identified by GWAS to be associated with waist-to-hip ratio [19], may provide insight into the relationship between obesity and RCC ...
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Genetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: A quantitative and molecular genetic investigation
... We have recently reported high heritability and genetic association between specific risk alleles and ADHD symptom scores in a population sample of 2- year old twins, with modest evidence of association being found for ...
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Polymorphisms in Toll-Like Receptor 4 Underlie Susceptibility to Tumor Induction by the Mouse Polyomavirus
... Genome-wide SNP array, QTL mapping, and TLR4 genotyping. DNA from parental and 114 F2 mice were extracted and genotyped at the Partners Healthcare Center for Personalized Genetic Medicine (PCPGM) core at Harvard Medical ...
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Dietary obesity linked to genetic loci on chromosomes 9 and 15 in a polygenic mouse model
... Loci linked to sensitivity to dietary obesity were identified by Quantitative Trait Locus (QTL) analysis of two mapping populations derived from a cross between AKR/J and SWR/J mice. AKR/J mice are ...
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Extreme QTL mapping of monepantel resistance in Haemonchus contortus
... For this purpose, an experimental genetic cross, fol- lowed by genotypic and phenotypic characterization of progeny, is necessary to assess genome regions with the co-segregation of phenotypic traits with genetic markers ...
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Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q
... Quantitative phenotyping and genotyping of microsatellite mark- ers were done as previously described (31, 32). Mice were fasted z 15 h before collection of blood and time of killing at 3 h into the light phase of ...
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Detection and utilisation of associations between genetic markers and quantitative trait loci in radiata pine : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Forest Genetics and Breeding at Massey University, Palmerston North, New Zealand
... In forest trees which are nonnally outcrossing, inbreeding by self-fertilisation (selfing) generally has deleterious effects including reduced seed set, poor seed germination, and slow seedling growth. Inbreeding ...
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Susceptibility loci for murine HIV associated nephropathy encode trans regulators of podocyte gene expression
... sion quantitative trait locus [eQTL] mapping) has emerged as a powerful tool for elucidating molecular pathways downstream of disease-causing mutations ...inherited trait that is influenced by ...
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Haplotype analysis within quantitative trait locus affecting intramuscular fat content on porcine chromosome
... ABSTRACT: Previous results of fine mapping for quantitative trait loci affecting intramuscular fat content identified a 3.0-Mb chromosome interval on porcine chromosome 7, which contains at least 9 genes, ...
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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats A chromosome 2 locus influences the response to a calcium antagonist
... a quantitative trait locus was identi- fied and mapped on rat chromosome 2 that specifically in- fluences the systolic (peak LOD score ...The locus accounted for ...the locus had no ef- ...
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Developmental Change of Vegetative Plant Architecture of Annual Form Wild Rice (Oryza rufipogon Griff ) Elevates Competitive Ability during the Late Development under a Dense Condition
... rice. Quantitative trait locus (QTL) analyses identified that one of the two QTLs associated with DC-TA shared a linked molecular marker with a QTL associated with SC-WDS only under H ...
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Identification of glucosinolate profile in Brassica oleracea for quantitative trait locus mapping
... map Quantitative Trait Loci for individual glucosinolates within Brassica oleracea mapping ...the quantitative measurements of glucosinolates, an optimized level of glucotropaeolin was used as an ...
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Honesty, power and bootstrapping in composite interval quantitative trait locus mapping
... Based on the results of this study and those of Li et al. [8] it seems likely that false QTL are a common feature of composite interval mapping studies that have used Zmapqtl Model 6 of QTL Cartographer. The false posi- ...
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Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
... suggesting that sickle cell trait had a stronger protection effect against SEV [OR 0.15 (0.09–0.27)] than against UM [OR 0.50 (0.30–0.84)] (Table 2). The transmission dis- equilibrium test (TDT) showed a ...
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Mapping quantitative trait loci in humans: achievements and limitations
... in trait values between members of a sibling pair (Y) as the dependent variable and the number of alleles shared IBD between them (X) at the marker locus (marker IBD score) as the independent ...marker ...
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Quantitative trait locus mapping of genes that control body length and plasma insulin like growth factor 1 level in mice
... Paigen B, Yuan R: Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains. Aging Cell 2010, 9:823 – 836. 31. Adamo ML, Ma X, Ackert-Bicknell CL, Donahue LR, Beamer WG, Rosen CJ: ...
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Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma
... Survival following a diagnosis of multiple myeloma (MM) varies between patients and some of these differences may be a consequence of inherited genetic variation. In this study, to identify genetic markers associated ...
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