Type 2 Diabetes Mellitus (T2DM) is a disorder in which there is inefficient use of insulin hormone, leads to build up of glucose in the blood and eventually ends up with hyperglycemia. The aim of this study was to test the hypothesis of inter-relationship of age, body mass index (BMI), randombloodsugar (RBS), Total Cholesterol (TC), Triacylglycerols (TAGs), High Density Lipoproteins cholesterol (HDLc), and Ca in patients with T2DM and also to compare these levels with that of healthy controls. Plasma glucose, serum TC, TAGs, HDLc, and Ca were estimated according to the instructions given in the methods. BMI was significantly higher and also the levels of RBS, TC and TAGs were significantly higher in T2DM patients compared with healthy controls. In addition, total serum Ca level was significantly higher in T2DM patients compared with healthy controls. No significant differences were observed in age and HDLc levels in T2DM patients compared with healthy controls. In the patient group positive correlation was observed between age and TAGs, age and HDLc, RBS and TC, RBS and TAGs, RBS and HDLc. In the control group, we found positive correlation between age and HDLc and a negative correlation between BMI and serum Ca. The authors conclude from the study that alterations in the study parameters in T2DM group are due to hyperglycemia, deficient scavenging action of HDLc and increase in serum calcium. Therefore, in patients with T2DM, any compensation mechanism may become insufficient.
Longitudinal mixed study in San Diego, California, with the database contains 2000 to 2002 found that the variable age, duration of disease, total cholesterol, BMI, dietary and malnutrition were significantly associated with glucose level and with the experience of longitudinal study on diabetes, many factors are associated with type-1 diabetes. Those are age, gender, treatment, diabetes duration, body mass index (BMI), exercise, insulin dose, family history, duration and others. There was a significant correlation between the total insulin secretory response and control of glucose, measured by HbA1c (P = 0.003) and insulin secretory response is an important determinant of the rate of metabolic decomposition from autoimmune destruction (11). The main objective of this study was to assess the risk factor for developing type-1 diabetes mellitus in pediatric patients over time using the randombloodsugar in a follow up study at Hiwot Fana specialized hospital during treatment period of 3 years and to determine their relationship and also to determine outcome of type-1 diabetes mellitus in pediatric patients. Parts of the paper are organized as follows. Section 2 describes the materials and methods used in the study, section 3 presents the results and discussion and conclusions are provided in section.
GDM are an important breakthrough as it allows detection of such a state with single prick. Currently there is lack of data supporting use of Glycosylated haemoglobin A1C or RandomBloodSugar (RBS) as a screening tool for detection of GDM in Indian women. There is an apparent need for a universally acceptable, much simpler and accessible test for GDM screening in first trimester. Glycosylated HbA1c is currently a good measure to know sugar control. 5
endocrine system in the human body, especially the regulation of blood glucose levels. The mechanism for increasing blood glucose levels is very complex. One opinion held is that anesthetic drugs directly suppress pancreatic beta cells through the release of catecholamines and result in decreased insulin production, while propofol will not increase bloodsugar levels because it suppresses or decreases the stress response so that the levels of catecholamines and cortisol decline. 20
One of the nonpharmacological treatments that can be used by people with diabetes mellitus type 2 is to consume alkaline water with PH > 7. Results of re- search conducted by Kuwata Keijiroo , in patients given alkaline water for 1 month, from laboratory results obtained Sugar in blood and urine ranges from a ratio of 300 mg/l to 2 mg/dc. There was a time in which the patient had under- gone 5 to 6 blood test days and was detected within the normal range. Results also showed that even 1 1/2 hours after eating, bloodsugar and urine ratio was 100 mg/dc: 0 mg/dc. This research is similar to the research done by Rosa Misti- ca , from the result of induction of metabolic disease in experimental animal, giving AIW (Alkaline Ionized Water) able to decrease glucose, total cholesterol and triglyceride level 11.15. Similar results conducted by Kim et al., AIW (Alka- line Ionized Water) are able to decrease abnormal glucose and blood lipid levels . Nonpharmacological therapy as a companion of pharmacological therapy in diabetes mellitus type 2 should begin to be developed considering that the level of adherence of diabetes mellitus type 2 patients in experiencing therapy is still in the low category. The purpose of this study is to analyze the effectiveness of alkaline water consumption to decrease randombloodsugar levels in people with diabetes mellitus type 2.
AIM: The current study is based on determination of high bloodsugar from different sample collected from outpatients and inpatients above 35 years old at Global hospital found in Chennai -Tamilnadu by using different tests such as: randombloodsugar, fasting bloodsugar, postprandial bloodsugar, glucose tolerance and glycosylated haemoglobin tests.
Conclusions: Authors formulate the hypothesis that glycated hemoglobin and randombloodsugar at admission correlate well with the outcome and adequacy of dialysis in patients of stage 5 chronic kidney disease undergoing haemodialysis. Good glycemic control (HbA1c <6.5 % and RBS <120 mg/dL) have shown to be important predictive markers of adequate dialysis. The hypothesis needs to be tested with a larger study.
Background: Multiple Sclerosis, a chronic inﬂammatory and neurodegenerative disease of the central nervous system, characterized by recurrent relapses of central nervous system inﬂammation ranging from mild to severely disabling. Relapses have treated with steroids to reduce inﬂammation and hasten recovery. However, the commonly used intravenous methylprednisolone in a dose 500mg_1000mg for 5days. Objectives: Assessment of relationship between the dose of intravenous methylprednisolone (500mg) and (1000mg) and side effects for treatment of patients with relapses of multiple sclerosis. Methods: A prospective case controlled study was carried on 40 patients who had multiple sclerosis relapse confirmed by kuratzke expanded disability status scale. Patients were divided into 2 groups first group involved 20 patients treated with (500 mg IV methylprednisolone) for 5 days. The second group involved 20 patients treated with (1000mg IV methylprednisolone) for 5days. Serum randombloodsugar, WBC counts before and after 1 and 6 weeks of the study and clinical examination for side effects. Results: The results showed that a non-significant difference WBC counts, while there was a significant increase in Serum randombloodsugar level in group 2 after one week of treatment with 1000mg IV methylprednisolone for 5 days in comparison with pretreatment. However, there was a non-significant difference in Serum randombloodsugar and WBC counts in group 1 after one week of treatment with 500mg IV methylprednisolone for 5 days in comparison with pretreatment. After six weeks of treatment, there was a non-significant change in Serum randombloodsugar and WBC counts for patients in both treated groups compared to pre-
Type 2 diabetes mellitus clinical features are Polyuria, polydipsia, polyphagia, fatigue, genital itching, decrease wound healing. This can be diagnosed with help of randombloodsugar, fasting bloodsugar, post parndial bloodsugar, urine test and glycosylated haemoglobin test. Type 2 diabetes mellitus complications are microvascular (retinopathy, nephropathy, neuropathy), skin and macro vascular complications (cardiac, cerebral). 
the diagnostic criteria as recommended by the American Diabetes Association for diabetes and International Diabetes Federation for metabolic syndrome, were recruited from the inpatient department of Kasturba Medical College hospital, Manipal University to the cross sectional study. Exclusion criteria for cases were individuals with type 1 diabetes, malignancy, acute infections, inflammation, endocrine disorders like hypothyroidism, patients on insulin therapy and chemotherapeutic agents, patients with confirmed neoplastic changes, old, sick and pregnant patients. Inclusion Criteria for controls were: fasting bloodsugar (FBS) <126 mg/dl, post prandial (PPBS) and randombloodsugar (RBS) <200 mg/dl, glycemic index (HbA1c) < 6.5% without family history of diabetes. Controls with atleast one feature of metS were excluded for metS controls.
Venous blood sample was collected from each subject and 1.0 ml of the blood was added to dipotassium ethylene diamine tetra acetic acid (EDTA) to the final concentration of 1.5 mg/ml while 2.5 ml of the blood was put in the sterile plain bottle to obtain serum. EDTA sample was used for the determination of packed cell volume using micro-haematocrit method  while the serum was used for the analyses of randombloodsugar (RBS) by RANDOX glucose oxidase method [28,29], urea by RANDOX Urease- Berthelot method [30,31] and creatinine using Jaffes method [32,33].
This is a prospective study carried out on 60 patients attending Diabetic clinic and ENT Outpatient department of Durgabai Desmukh Hospital and Research Centre, Vidyanagar, Hyderabad, Telangana; were subjected to pure tone audiometry and evaluation of randombloodsugar, glycolslated hemoglobin, lipids, creatinine. The prevalence of SNHL with relation to age, sex, duration and control of diabetes were analysed over a period of 2 years from may 2016 to may 2018.
Duration of diabetes does not have any effect on causation of glaucoma, however high randombloodsugar level increases the severity of glaucoma in diabetic patients. Thus severity of glaucoma can be controlled by proper management and control of diabetes. REFERENCES
Some drugs of trial drug like Giloy, Punarnava, Gomutra have Raktavardhaka property and Amalaki has Vit.C alkaloid that is useful in absorption of iron, due to these properties trial drug is helpful in increasing Haemoglobin and Platelet count. Present study reveals significant (p<0.05) result in both the groups in increasing haemoglobin and platelet count but study shows not significant (p>0.05) result in TLC. Some drugs of trial drug like Rasna, Aprajita have Vishghna (Detoxifying) property they are helpful in reducing urinary problems that’s why present study reveals significant (p<0.05) result in Blood Urea in group A and very significant (p<0.01) result in group B but the present study shows not significant(p>0.05) result in reducing serum creatinine in group A and very significant(p<0.01) result in group B in reducing Serum Creatinine level. Some drugs of trial like Giloy, Haritaki, Amalaki, Mandookparni, Punarnava have hepatoprotective action thast’s why these drugs are helpful in maintaining liver functions. Present study reveals not significant (p>0.05) result in group A and very significant (p<0.01) result in group B in reducing Serum alkaline phosphatase. Study reveals Not significant (p>0.05) result in reducing Serum bilirubin total and SGPT in both the groups. May be the toxicity level of CT/RT is very high sample size is very small that’s why present study shows not significant (p>0.05) result in these parameters but present study reveals significant(p<0.05) result in reducing SGOT in group A and not significant (p>0.05) result in group B. Some drugs of trial drug like Haritaki have hypolipidamic properties thats why may be the trial drug show very significant (p<0.01) result in reducing Serum triglycerides in group A but not significant(p>0.05) in group B. Trial drug reveals not significant (p>0.05) result in both groups in serum cholesterol. Present study reveals significant (p<0.05) result in group A but not significant (p>0.05) result in group B in reducing Randombloodsugar may be the reason is chemo-radio drugs also have hypoglycaemic effect and trial drug also contents like Amrita, Aprajita, Rasna, Amalaki, Hariaki, Mandookparni, Gomutra these drugs are Tikta Kshaya Rasa Pradhana drugs that’s why trial drug also have hypoglycaemic properties.
Background: Diabetes hastens the onset of cataract, so a patient may get diagnosed of cataract and diabetes at the same time. Checking of randombloodsugar values for all patients presenting with visual loss will be both a primary and secondary prevention strategy of diabetes, where in we could diagnose diabetes early and treat it promptly. Methods: This is a Health centre based cross sectional study done in Anakaputhur-urban field practice area of Sree Balaji Medical College and in Kanchipuram district, Tamil Nadu from September 1st to November 30th 2016, including people with visual complaints of all age groups in the study area, excluding severely ill, mentally challenged and those not willing to participate in the study. Based on convenient sample size calculation, prevalence was assumed to be 50%, with confidence interval 95%, relative precision was 9%, the sample size was calculated to be 494 participants. Previous health centre records dated September 1st to November 30th 2016the data was entered in MS excel and analaysed in SPSS 20 version.
Anthropometric parameters of the subjects i.e. Blood pressure was measured using a mercury sphygmomanometer to the right arm while the individuals were in a sitting position. The participant's weight and height was measured without shoes. BMI was calculated as weight (kg) divided by the square of height (m2). The waist circumference measurement was taken at the end of expiration and in between the midpoint of the last rib and superior iliac crest.
principles of diagnosis and treat- A 65 years old female patient, known case of DM for 24 years, with bilat- ion, nausea, vomiting, weakness and hiccups visit- ed hospital. Her renal and diabetic profiles were deranged (serum creatinine 3.0 mg/dl, blood urea 50 mg/dl, bloodsugar fasting 245 mg/dl and post prandial 345 mg/dl) with protein urea. Patient was taking oral hypoglycemic agent and insulin. She was case of diabetic nephropathy. According to principles of Ayurveda she was diagnosed . She received combination of hajratyahud each 250 mg before food twice daily, fresh decoction of 50 ml twice daily and chandraprabha vati 500 mg before food twice daily. Outcome: After ptoms. Significant drop down was seen in renal profile and sugar (serum creatinine1.1 mg/dl, blood urea 40 mg/dl, bloodsugar fasting 114 mg/dl, post prandial : Significant relief can be achieved in patients of nephropa-