rapid progressors
R5 Strains of Human Immunodeficiency Virus Type 1 from Rapid Progressors Lacking X4 Strains Do Not Possess X4-Type Pathogenicity in Human Thymus
... Although our data suggest that R5-AIDS viruses are not as pathogenic as X4 viruses, it is quite possible that R5-AIDS viruses are more pathogenic than “regular” R5 viruses. In another study of R5 virus pathogenesis in ...
6
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
... slow progressors, exhibits low production of cytokine, and is marked by elevated expression of multiple inhibitory receptors and reduced proliferative capacity compared with islet-specific cells from rapid ...
12
Epstein Barr virus specific cytotoxic T cell responses in HIV 1 infection: different kinetics in patients progressing to opportunistic infection or non Hodgkin's lymphoma
... very rapid progressors to AIDS was the complete loss of T cell function and a simultaneous rapid decline of HIV-1– and EBV-specific CTLp observed, indicative for total collapse of cellular ...
10
Transcriptomic meta analysis identifies gene expression characteristics in various samples of HIV infected patients with nonprogressive disease
... RP: rapid progressors; ART: antiretroviral therapy; DEGs: differentially expressed genes; DAVID: database for annota‑ tion, visualization and integrated discovery; GEO: gene expression omnibus; GO: gene ...
10
Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.
... slow progressors than in the rapid progressors by both statistical treatments for all years of the study as well as for year 1 and year 2 alone (Table ...slow progressors at all time points by ...
9
Laser Capture Microdissection Assessment of Virus Compartmentalization in the Central Nervous Systems of Macaques Infected with Neurovirulent Simian Immunodeficiency Virus
... into rapid and conventional progressors based upon the rate of disease ...conventional progressors devel- oped neurological symptoms at a later stage of the disease course, typically within 10 months ...
13
Identification of progressors in osteoarthritis by combining biochemical and MRI based markers
... There is presently no disease-modifying osteoarthritis drug (DMOAD) with a consistent, documented effect despite sev- eral clinical attempts in late-stage phases. Some studies may have failed due to suboptimal clinical ...
11
Alterations in Cardiac and Pulmonary Function in Pediatric Rapid Human Immunodeficiency Virus Type 1 Disease Progressors
... function. Rapid progressors, both in the prospective group and group I, had faster heart rates, lower fractional shortening, and higher respiratory rates (Fig ...
10
Macaques with Rapid Disease Progression and Simian Immunodeficiency Virus Encephalitis Have a Unique Cytokine Profile in Peripheral Lymphoid Tissues
... among rapid progressors the inci- dence of SIVE was increased with approximately 50% of these animals demonstrating characteristic CNS lesions ...among rapid and slow/normal progres- sors, when ...
5
Early HLA-B*57-Restricted CD8+ T Lymphocyte Responses Predict HIV-1 Disease Progression
... including rapid progression, viremic slow progression, and elite ...slow progressors and B57 ⴙ rapid progressors have largely focused on cytotoxic T lymphocyte (CTL) phenotypes and ...
12
HIV 1 subtype C envelope characteristics associated with divergent rates of chronic disease progression
... between progressors and slow progressors including cor- responding study entry and exit time-points were identi- fied using VESPA (Viral Epidemiology Signature Pattern Analysis) ...
12
A possible role for CCR5 in the progression of atherosclerosis in HIV-infected patients: a cross-sectional study
... We used the LOGIQ 700 ME system (General Electric) to obtain normalised values IMT [1,6]. We identified and digitally recorded the far wall of the common carotid ar- tery (1 cm proximal to the bifurcation), the carotid ...
9
KIR3DS1/L1 and HLA Bw4 80I are associated with HIV disease progression among HIV typical progressors and long term nonprogressors
... HLA-Bw4-80I, the ligand for the KIR3DL1 receptor and the putative ligand for the KIR3DS1 receptor, has been reported to be associated with HIV disease pro- gression. Flores-Villanueva, et al. reported that, among ...
11
Alterations of Natural Killer Cell and T-Lymphocyte Counts in Adults Infected with Human Immunodeficiency Virus through Blood and Plasma Sold in the Past in China and in Whom Infection Has Progressed Slowly over a Long Period
... Among human immunodeficiency virus (HIV)-infected per- sons, a small percentage maintaining CD4 T-cell counts of ⬎ 500 cells/ l for more than 10 years without receiving anti- retroviral therapy are known as long-term ...
5
Meta-analysis of gene expression profiles in long-term non-progressors infected with HIV-1
... Background: In the absence of antiretroviral treatments (ARTs), a small group of individuals infected with HIV, including long-term non-progressors (LTNPs) who maintain high levels of CD4+ T cells for more than 7 ...
10
Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages
... Blood (20 ml EDTA) was obtained from 26 HIV+ individ- uals attending HIV clinic at the Westmead Hospital (Table 1) and 5 HIV- healthy individuals from the Australian Red Cross, Sydney. This study has been approved by the ...
13
Expediting systematic reviews: methods and implications of rapid reviews
... of rapid review methods were found; exemplars were chosen to demonstrate maximal variability in terms of methods used for rapid reviews found within this litera- ture search (Table S1, Additional file ...
10
Evaluating the American Academy of Pediatrics Diagnostic Standard for Streptococcus pyogenes Pharyngitis: Backup Culture Versus Repeat Rapid Antigen Testing
... pyogenes rapid antigen test with a backup culture if the rapid antigen test was negative, was shown in this study to be ...the rapid-culture strategy sensitivity is significantly higher than the ...
7
Role of CD4+ and CD8+ T-Cell Responses against JC Virus in the Outcome of Patients with Progressive Multifocal Leukoencephalopathy (PML) and PML with Immune Reconstitution Inflammatory Syndrome
... Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the brain caused by JC virus (JCV). To assess the role of CD4 ⴙ and CD8 ⴙ T-cells against JCV in the clinical outcome of PML and PML ...
8
Comparison of Three Commercial Rapid Identification Systems for the Unusual Gram Positive Cocci Dolosigranulum pigrum, Ignavigranum ruoffiae, andFacklamia Species
... pigrum, Facklamia species, and I. ruoffiae cultures were posi- tive. However, in the ID32 test, two strains of D. pigrum, one strain of F. hominis, four strains of F. ignava, two strains of F. languida, and one strain I. ...
6