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rat models

Antihyperglycemic Activity of Moringa oleifera Lam Leaf Functional Tea in Rat Models and Human Subjects

Antihyperglycemic Activity of Moringa oleifera Lam Leaf Functional Tea in Rat Models and Human Subjects

... in rat models and in human subjects. In rat models the antihyperglycemic ef- fect was more pronounced 90 min after glucose loading and more so at doses of 20 ml/kg BW which impaired blood ...

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Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

... three models was found for 1,233 Affymetrix probe sets representing 713 known genes and 468 expressed sequence tags (ESTs) and predicted genes (see Additional file ...

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Modeling Alzheimer's disease with non-transgenic rat models

Modeling Alzheimer's disease with non-transgenic rat models

... animal models of AD were developed based on impairing central cholinergic function to reproduce the alterations of cognitive performance seen in ...the rat occipital cortex ...nergic-based rat ...

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Pharmacological evaluation of antidiabetic and antihyperlipidemic activity of Chenopodium album root extract in male Wistar albino rat models

Pharmacological evaluation of antidiabetic and antihyperlipidemic activity of Chenopodium album root extract in male Wistar albino rat models

... Aim: The roots of Chenopodium album Linn (C. album) are traditionally used for the treatment of diabetes. In the present communication, we investigated the antidiabetic effect of methanolic extract of C. album roots in ...

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Original Article Generation and evaluation of three rat models with alcoholic osteoporosis

Original Article Generation and evaluation of three rat models with alcoholic osteoporosis

... animal models for osteoporosis are postmenopausal osteoporosis, disuse osteopo- rosis and glucocorticoid-induced osteoporosis [6, ...animal models of alcohol-induced osteoporosis have been sug- gested. ...

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Experimental rat models of chronic allograft nephropathy: a review

Experimental rat models of chronic allograft nephropathy: a review

... In rat models of CAN, impairment of renal function and histopathol- ogy similar to that described in humans can be produced in a few months, allowing investigators to study its pathology within a reasonable ...

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Overview of Promising Rat Models for Cortical Lesion Research- 2006 Until Now

Overview of Promising Rat Models for Cortical Lesion Research- 2006 Until Now

... few models resemble cellular features of the progressive disease form of MS (like cortical demyelination) and if they do observable lesions are rather sparse and short ...animal models delayed and ...

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Ranking candidate genes in rat models of type 2 diabetes

Ranking candidate genes in rat models of type 2 diabetes

... using rat mod- els, two different inbred strains have been utilised, Goto- Kakazaki (GK) and Otsuka Long-Evans Tokushima fatty ...diabetic rat strains ...diabetes models include glucose level, ...

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Genetic Rat Models of Schizophrenia Relevant Symptoms

Genetic Rat Models of Schizophrenia Relevant Symptoms

... animal models is essential for the research on the neuro- biological mechanisms of (and treatments for) psychiatric disorders, even when these are as com- plex as ...and rat) models have behavioural ...

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Atherosclerosis Vaccine Using BacteriaSalmonellatyphimuriumon Rat Models

Atherosclerosis Vaccine Using Bacteria Salmonella typhimurium on Rat Models

... This research was a true experimental with randomized posttest only control group design and carried out on rat models. Twenty male Wistar rats (6-8 weeks) were divided into five groups: a group that had ...

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Transgenic rat models for mutagenesis and carcinogenesis

Transgenic rat models for mutagenesis and carcinogenesis

... transgenic rat models for mutagen- esis and carcinogenesis are useful tools for various purposes such as regulation of chemicals, chemopreven- tion studies and mechanistic ...transgenic rat ...

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COMPARISON OF PATHOGENESIS OF P. BERGHEI INFECTION IN MOUSE AND RAT MODELS

COMPARISON OF PATHOGENESIS OF P. BERGHEI INFECTION IN MOUSE AND RAT MODELS

... the rat survival model and its low level in the murine severe model during peak parasitemia could also point to a crucial role for IL-4 as a contributing factor for survival during ...

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Anticonvulsant Activity of Quinine in Rat Models of Seizure in Comparison With Valproate and Phenytoin

Anticonvulsant Activity of Quinine in Rat Models of Seizure in Comparison With Valproate and Phenytoin

... its novel anticonvulsant mechanism cannot be neglected keeping in mind the ever-increasing problem of refractory epilepsy. In this context, quinine might be useful as a rescue drug for refractory seizures and ...

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GASTRODUODENAL ULCER PROTECTIVE AND BIOCHEMICAL STUDY OF HELIOTROPIUMINDICUM ON EXPERIMENTAL RAT MODELS

GASTRODUODENAL ULCER PROTECTIVE AND BIOCHEMICAL STUDY OF HELIOTROPIUMINDICUM ON EXPERIMENTAL RAT MODELS

... A peptic ulcer is an excoriated area of the mucosa caused by the digestive action of gastric juice in the stomach. The peptic ulcer is gastrointestinal tract multi factorial disease, which caused by tobacco smoking, ...

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Antiulcer and Anti-Inflammatory Activities of Utleria Salicifolia Leaves in Rat Models

Antiulcer and Anti-Inflammatory Activities of Utleria Salicifolia Leaves in Rat Models

... Evaluation of turmeric has been done for gastric and duodenal antiulcer activity in rats.Volatile oil of Curcuma longa possess anti-inflammatory and anti-arthritic activities. Water and fat soluble extracts of curcumin ...

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Non Obese Type 2 Diabetic Rat Models GK Rat and SDT Rat

Non Obese Type 2 Diabetic Rat Models GK Rat and SDT Rat

... one of the most severe ocular complications. Currently, there is no animal mod- els show neovascular glaucoma. SDT rats with advanced retinopathy developed fibrovascular membrane around the iris and sometimes with ...

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Original Article 2-BFI inhibits hippocampal neuron apoptosis and NMDA receptor expression in chronic epileptic rats

Original Article 2-BFI inhibits hippocampal neuron apoptosis and NMDA receptor expression in chronic epileptic rats

... have a significant antiepileptic effect [17-19]. Our previous studies show that, compared with agmatine, 2-BFI is another I2R ligand with potent and long-lasting neuroprotective effects against glutamate-induced ...

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Modeling Alzheimer’s disease in transgenic rats

Modeling Alzheimer’s disease in transgenic rats

... The rat is, in many aspects, closer to humans than ...current rat transgenic models, while replicating all as- pects of the amyloid pathology including inflammation and the presence of dystrophic ...

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Retinal, visual, and refractive development in retinopathy of prematurity

Retinal, visual, and refractive development in retinopathy of prematurity

... and rat models of ...In rat models, rod photoreceptor dys- function is detectable before retinal vascular abnormalities ...of rat models shows that ...

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Effect of Storage Processes on the Bacterial Growth-Inhibiting Activity of Human Breast Milk

Effect of Storage Processes on the Bacterial Growth-Inhibiting Activity of Human Breast Milk

... bacterial growth-inhibiting activity, however, even with freezing, differs in this respect from the rat models and suggests that other potential functional aspects of human breast milk ([r] ...

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