Regulatory Element Binding Protein-1
Activation of sterol regulatory element binding protein 1 (SREBP1) mediated lipogenesis by the Epstein Barr virus encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma
... membrane protein 1 (LMP1), which is commonly expressed in NPC, engages multiple signaling pathways that promote cell growth, transformation, and metabolic ...sterol regulatory ...
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Sterol regulatory element binding protein 1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer
... Sterol Regulatory Element Binding Protein-1 gene (SREBP1) expression in PCOS and EC endometrium, and to correlate endometrial SREBP1 expression with serum lipid ...
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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein 1 in human and mouse organs and cultured cells
... The 5' end of the mRNA-encoding sterol regulatory element binding protein-1 (SREBP-1) exists in two forms, designated 1a and 1c. The divergence results from the use of two ...
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Human Cytomegalovirus Infection Induces Adipocyte-Like Lipogenesis through Activation of Sterol Regulatory Element Binding Protein 1
... for 1 h, followed by incubation with 10 g/ml of anti-SREBP1 antibody (IgG-2A4; BD FIG 1 (A) The glycolytic, glutaminolytic, fatty acid, triglyceride, and cholesterol biosynthetic pathways discussed in the ...
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The pattern of development for gene expression of sterol regulatory element binding transcription factor 1 in pigs
... (sterol regulatory element-binding tran- scription factor 1) is a member of the basic he- lix-loop-helix leucine zipper (bHLH-LZ) family of transcription ...sterol regulatory ...
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Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivity
... Sterol regulatory element-binding protein 1 (SREBP1) is a membrane-bound TFs that belongs to a family of basic helix-loop-helix-leucine zip- per (bHLHLZ) TFs ...sterol regulatory ...
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Plastic Surgery Update on the Biology of Fat Cells and Adipose Derived Stem Cells for Fat Grafting
... morphogenetic protein-4) signaling pathway; Smad family (Trans-cytoplasmic protein receptors); Rock2 (RHO-associated kinase); YAP (Yes-associated protein transcriptional factor); TAZ (Transcrip- ...
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Impact of dietary protein on lipid metabolism-related gene expression in porcine adipose tissue
... palmitoyltransferase 1 (CPT-1) are rate limiting enzymes in catabolism, responsible for hydrolysis of triglycerides and importing esters of fatty acids to mitochondria for b-oxidation ...sterol ...
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Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid
... The liver plays a central role in the control of glucose and lipid metabolism. People with obesity are always ac- companied by increased plasma FFA levels. An oversup- ply of FFA to the liver may affect glucose ...
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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
... taining three copies of SRE-1 (three copies of repeats 2 and 3 from the LDL receptor promoter). This construct has been shown previously to be extremely sensitive to the level of SREBP in the nucleus (17). In the ...
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Sterol regulatory element binding protein is a crucial regulator of natural killer cell metabolism and function
... Another transcription factor with an important role in regulating cellular metabolism in T cells is HIF (Hypoxia-inducible factor) is a heterodimeric transcription factor consisting of an oxygen-regulated alpha subunit ...
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Role of Polypyrimidine Tract Binding Protein in the Function of the Hepatitis B Virus Posttranscriptional Regulatory Element
... PTB binding in PRE function. The binding of PTB to fragment III does not necessarily reflect a role for PTB in PRE ...PTB binding, we performed two sets of ...PTB binding on PRE func- tion by ...
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Prolactin Regulatory Element Binding Protein Is Involved in Hepatitis C Virus Replication by Interaction with NS4B
... into the HCV replication complex by NS4B, we investigated the effect of PREB silencing on the formation of the membrane web. SGR2a cells were treated with siPREB or siNT and analyzed by transmission electron microscopy ...
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Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance in Cryptococcus neoformans
... to 1% oxygen and 5% CO 2 at 37°C. Al- though 1% oxygen conditions rarely occur in a healthy human body, we chose such a stringent oxygen condition as our screening criterion in order to exclude mutants ...
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FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c
... nuclear protein sub- family that includes four homologous proteins in mam- mals: FoxO1, FoxO3, FoxO4 and ...DNA binding domain ...FoxO3 protein [14, ...file 1: Figure ...
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Regulation of bone by the adaptive immune system in arthritis
... activator protein 1; CNS2, conserved noncoding sequence 2; CREB, cyclic adenosine monophosphate responsive-element-binding protein; EAE, experimental autoimmune encephalomyelitis; ...
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Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
... Several lines of evidence indicate the involvement of the Akt/mTORC1 signaling axis in the regulation of SREBP. We have shown that mTORC1 is required for the nuclear accumulation of mature SREBP1 in response to Akt ...
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<p>Therapeutic targets of hypercholesterolemia: HMGCR and LDLR</p>
... mitogen-activated protein kinase 1 (MEK1)/ERK-PCSK9 ...cer binding protein (c/EBP), cAMP-responsive element binding protein (CBP) and early growth response gene 1 ...
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Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts
... iron regulatory protein 1 (IRP1) was activated, and increased IRP2 levels, indicative of relative cytosolic iron depletion, were observed together with mitochondrial iron ...
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Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
... Activator protein 1; ARE: Androgen receptor element; C/EBP α : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate responsive ...
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