Regulatory roles
Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C Terminal Processing Proteases
... To understand the structural basis for the activating role of the PDZ domain in regulating the activity of Prc, we have determined a set of crystal structures in the unliganded resting state of Prc, alone or in complex ...
12
Multiple regulatory roles of AP2/ERF transcription factor in angiosperm
... AtERF8 had been found to be associated with plant aging (Koyama et al. 2013). Of these three genes, AtERF4 and AtERF8 belonged to class II ERFs in Arabidopsis, which can accelerate precocious leaf senescence by targeting ...
8
Cross regulatory roles of interleukin (IL) 12 and IL 10 in atherosclerosis
... There is ample evidence to suggest that these cytokine pro- files contribute to the outcome of infectious disease. In various mouse models of infection, Th1 and Th2 T cell responses have been shown to determine ...
10
Traditional Chinese Medicine and regulatory roles on epithelial–mesenchymal transitions
... In this review, the physiological and pathological EMT driven processes are summarized and the regulatory roles of TCM herbs and prescriptions on these pro- cesses are studied. The complexity of the EMT ...
13
Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney
... the regulatory roles of Nrf2 in the kidney, we performed integrated transcriptomic and proteomic analyses of kidney tissue from wild-type and Nrf2 knockout mice treated with the Nrf2 inducer methyl-2-cyano- ...
13
Regulatory interaction and the adoption of regulatory roles in teams at the workplace
... the regulatory roles played in team interactions at the workplace, and whether these roles are beneficial for the teams’ ...regarding regulatory roles in team interactions, the research ...
29
The regulatory roles of neutrophils in adaptive immunity
... inflammatory roles of neutrophils have been well recognized for long, neutrophils indeed play a direct suppressive role on proinflammatory cytokine productions through different ...of regulatory T cell ...
11
Emerging Regulatory Roles of Dual-Specificity Phosphatases in Inflammatory Airway Disease.
... The specific roles of each MAPK pathway have been examined using small molecule inhibitors. Pyridinyl imidazole compounds inhibit p38 by competing with ATP for its binding site, blocking its catalytic activity ...
24
Regulatory roles of IL 10 producing T follicular cells
... Despite lack of FOXP3 expression, CD25+ TF cells resemble Tregs in high CTLA4 expression, low IL-2 production, and their ability to repress T cell proliferation.. IL-10 boosts conversion[r] ...
133
Placental genomics: regulatory roles of histamine in pre-eclampsia
... the roles of genes with consistent low or high level expressions in the ...contributory roles or causal effects of elevated histamine in the pathogenesis of ...possible roles in the molecular ...
181
<p>A Systemic Review on the Regulatory Roles of miR-34a in Gastrointestinal Cancer</p>
... GBC is one of the most common malignant gastrointestinal tumors in the world, accounting for 80 – 95% of global biliary carcinoma, and is also the main cause of global biliary malignant tumor-related death. 169 – 171 GBC ...
18
Virulence of methicillin-resistant Staphylococcus aureus modulated by the YycFG two-component pathway in a rat model of osteomyelitis
... two-component regulatory pathway is associated with the bacterial biofilm organization of MRSA ...the regulatory roles of AS yycG in the bacterial biofilm formation and the pathogenicity of MRSA ...
10
T box transcription factors and their roles in regulatory hierarchies in the developing heart
... The mammalian heart is a mechanical pump that can be viewed developmentally as a highly modified muscular vessel. The atria are collecting chambers and the ventricles pumping chambers. Valves separate chambers and guard ...
14
Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism
... The velvet proteins VosA (viability of spores A) and VelB (velvet-like B) can form homodi- mers as well as the VosA-VelB heterodimer to repress or activate gene expression [2,6–9]. VosA represses brlA (bristle A) ...
45
Accountability and Risk Governance: A Scenario-informed Reflection on European Regulation of GMOs
... The present EU regulatory framework of GMOs is the result of regulatory reforms that took place between 2002 and 2004. In general, the authorization of GMOs is based on comitology, which is defined as ...
26
Overlapping Roles of the Cytoplasmic and Mitochondrial Redox Regulatory Systems in the Yeast Saccharomyces cerevisiae
... the roles of the glutathione (GSH)-glutaredoxin and thioredoxin sys- tems in maintaining the redox homeostasis of the cell (3, ...proposed roles in many cellular processes including protein folding and ...
9
The Hurunui Waiau Zone Implementation Programme as a collaborative planning process: A preliminary review
... Water conflicts in the 21 st century generally belong to the class of ‘wicked problems’ (Rittel and Webber 1973) which fail to be adequately resolved by regulatory agencies accountable to elected leaders. Water ...
42
Embryonic roles for the slug regulatory gene in hindbrain regeneration and limb patterning
... bias of slug expression early in limb bud development - the posterior bead is implanted into a 5/Mg-expressing region whereas the anterior bead is implanted proximal to th[r] ...
226
Human Cytomegalovirus Infection Interferes with the Maintenance and Differentiation of Trophoblast Progenitor Cells of the Human Placenta
... potential roles in self-renewal and dif- ferentiation (referred to as TBPC regulatory proteins) based on their known functions in mouse trophoblast progenitor cells and human embryonic stem cells ...
14
Primer Pairs for Rice (Oryza sativa L.) Bisulfite Sequencing Studies
... and regulatory sequences with different functions were ...and regulatory sequences using EpiOne software program ...contain regulatory regions such as promoters and ...
8