release characteristics
Emerging nanoparticulate systems: Preparation techniques and stimuli responsive release characteristics
... Nanotechnology has become an outgrowing field in novel drug delivery system. It confers several merits over conventional formulations like increased solubility and bioavailability, targeted drug delivery and a decreased ...
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EFFECT OF SINTERING CONDITION ON PHYSIO CHEMICAL PARAMETERS AND DRUG RELEASE CHARACTERISTICS FROM POLYMERIC MATRIX TABLET OF ATENOLOL FOR CONTROLLED RELEASE
... drug release characteristics from the sintered matrix ...Drug release rate from the prepared tablets were inversely related to the concentration of sintering polymer, sintering temperature and ...
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Experimental study of PLLA/INH slow release implant fabricated by three dimensional printing technique and drug release characteristics in vitro
... Local antibiotic drug delivery devices such as drug loading bone cement, bone screw and bone cement bradde chain played an important role in the prevention and treat- ment of bone infection [15-18]. The main point of ...
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STUDIES ON COMPRESSION AND DRUG RELEASE CHARACTERISTICS OF XANTHIUM GUM PELLETS OF DIFFERENT COMPOSITIONS
... the release characteristics of model drug and production of tablets for the sustained delivery of the Simvastatin, a set of twelve formulations were prepared shown in table 1, The pellets of Simvastatin was ...
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FORMULATION AND RELEASE CHARACTERISTICS OF HPMC MATRIX TABLETS OF METOPROLOL SUCCINATE
... drug release studies carried out with different formulation tablets in ...low release in gastric medium ...drug release was increased in intestinal fluid (pH ...drug release in compared to ...
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EFFECT OF CERTAIN POLYMERS ON THE RELEASE CHARACTERISTICS OF NIMODIPINE
... Nimodipine(NMD) is used in the treatment of various cardiovascular disorders such as angina pectoris, cardiac arrhythmia and hypertension. The major problem of this drug is its very low solubility in biological fluids as ...
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Enhanced osteogenic activity and anti-inflammatory properties of Lenti-BMP-2-loaded TiO<sub>2</sub> nanotube layers fabricated by lyophilization following trehalose addition
... surface characteristics, release characteristics, inflammatory cytokine suppression, and their effects on osteogenic dif- ferentiation and proliferation of bone marrow stromal cells (BMSCs) in vitro ...
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Formulation and in vitro and in vivo evaluation of film-coated montelukast sodium tablets using Opadry® yellow 20A82938 on an industrial scale
... immediate release characteristics of the obtained film coat were determined by subjecting the coated tablets to gastric pH, and drug release was analyzed using the HPLC ...MS release. In fact, ...
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Drug eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection
... drug release characteristics of TNT-Ti wires were evaluated, showing a two-phase release, with a burst release (37%) and a slow release with zero-order kinetics over 11 ...
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FORMULATION OF PIOGLITAZONE FLOATING TABLETS: A COMPARATIVE EVALUATION OLIBANUM, STARCH ACETATE AND HPMC K15M
... drug release from all these tablets was diffusion controlled. When the release data were analyzed as per Peppas 2 equation, the release exponent ‘n’ was found in the range ...the release ...
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“Biodegradable Polymer Based Nanoparticles: A Novel Approach” by S. G. Bhokare, R. P. Marathe, M. T. Gaikwad, P. B. Salunke, India.
... the release occurs by diffusion or erosion of the matrix under sink ...of release is largely controlled by a diffusion ...initial release or ‘burst’ is mainly attributed to weakly bound or adsorbed ...
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Preparation and Characterization of IPN Microspheres for Controlled Delivery of Naproxen
... drug release in 10 h, whereas IPN microspheres produced up to 80% cumula- tive release at the end of the 10 ...The release rates of NS to an ex- ternal medium are more difficult compared to the NaAlg ...
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Poly(n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats
... and QT-PBCA + P-80) or free QT were suspended in 2 mL of PBS (pH 7.4) using cellulose dialysis tube bags (with molecular weight cut-off size 12,000 Da). The bags were dipped into 200 mL PBS (pH 7.4) containing 0.01% ...
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Nanotechnological Contribution to Drug Delivery System: A Reappraisal
... Most of the current research focuses on utilizing nanoparticles as drug delivery vehicles in most chronic dis- eases like cancer, HIV and diabetes where treatment options are limited. Generally, nanoparticles are in the ...
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Studies on buccoadhesive tablets of terbutaline sulphate
... Each tablet was inserted in a metal die having a central hole of 8 mm in diameter so that the drug could be released only from the upper face of the tablet. Medium used for the release rate study was 500 ml of ...
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FORMULATION, DEVELOPMENT AND CHARACTERIZATION OF ORAL DISINTEGRAING TABLET OF CIMITIDINE HCL
... Cimitidine HCl is a recognized drug for peptic ulcer therefore development of an ODT of Cimitidine HCl and to evaluate the effect of various superdisintegrants on its disintegration time and release profile was ...
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Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers
... cilostazol has been formulated as immediate-release (IR) tablets. Because these tablets must be taken twice daily, attempts have been made to develop a sustained-release (SR) cilostazol formulation. The SR ...
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Fabrication and Characterization of Olopatadine Hydrochloride Loaded Bionanofibers as a Platform for Drug Delivery
... In-vitro release study showed that the fabricated bionanofibers are capable of controlled drug de- ...burst release of drug because of enormous surface area of the nano- fibers followed by controlled ...
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Biodegradable in situ gelling delivery systems containing pilocarpine as new antiglaucoma formulations: effect of a mercaptoacetic acid/N-isopropylacrylamide molar ratio
... drug release profiles exhibited noticeably distinct miosis action, thereby reflecting the importance of the characteristics of biodegradable in situ gelling systems on their treatment performance for ...
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Formulation and Evaluation of Nanoemulsion Gel of Tenoxicam For Topical Application
... The aim of the present study to develop a nanoemulsion gel formulation of poorly water soluble drug tenoxicam for the transdermal delivery. Nanoemulsions have the particle size range in nano range. Particle size in ...
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