Ret/antibody
The Drosophila Ret gene functions in the stomatogastric nervous system with the Maverick TGFβ ligand and the Gfrl co receptor
... CRISPR-induced Ret mutations. Mutations in the Drosophila Ret gene were induced using the CRISPR/Cas9 system and phenotypically ...(A) Ret gene with the genomic locations of the gRNAs (1*, 2/3*) ...
12
Yap and Taz are required for Ret dependent urinary tract morphogenesis
... 3 antibody revealed similar CND apoptosis rates in controls and mutants at ...anti-calbindin antibody was used to stain the Yap-depleted ureter ...anti-Pax2 antibody and DAPI was used to label the ...
8
Multiple Roles of Ret Signaling in Mechanosensory Neuron Development
... good antibody against Nmbr or behavior analysis with Nmb and Nmbr knockout mice in the future will help to address the localization of Nmbr and physiological roles of DRG neuron derived ...
252
Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret
... To determine the percentage of neurons expressing Isl1, GFP, Gfra1 and Gfra2 per ganglion, we prepared five adjacent sets of 12- m sections from L4 and L5 DRG from three E14.5 embryos per group, and then stained each ...
10
Apatinib inhibits cellular invasion and migration by fusion kinase KIF5B-RET via suppressing RET/Src signaling pathway
... secondary antibody for 1 h at room temperature, washed three times with TBST, and detected by enhanced chemiluminescence reagent (Pierce, Rockford, IL, ...against RET, p-RET, ERK, p-ERK, Src, p-Src, ...
9
EGF Induced RET Inhibitor Resistance in CCDC6 RET Lung Cancer Cells
... anti- RET, anti-phospho-RET, anti-EGFR, anti-phospho-EGFR, anti- AKT, anti-phospho-AKT, anti-ERK, anti-phospho-ERK, or anti- beta actin (1:1000; Cell Signaling Technology, Danvers, MA, USA) overnight at ...
10
RET mediated glial cell line derived neurotrophic factor signaling inhibits mouse prostate development
... primary antibody with antigenic peptide, when available, prior to incubation with secondary antibodies and incubation in the absence of primary antibodies (Park and Bolton, ...Millipore); RET (5 µg/ml, ...
12
The histone code reader SPIN1 controls RET signaling in liposarcoma
... SPIN1 antibody coprecipitated endogenous MAZ protein and MAZ antibody coprecipitated endogenous SPIN1 protein demonstrating interaction of both proteins (Figure 4D, ...
17
Exon skipping in the RET Gene encodes novel isoforms that differentially regulate RET Protein signal transduction
... 5. RET ⌬E3 and RET ⌬E345 can heterodimerize with full-length ...HA antibody to select for ...anti-FLAG antibody selected for FLAG:: RET51 ⌬E345 ...
16
Convalescent Plasmodium falciparum specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure
... global antibody level, breadth and magnitude of P. falciparum antibody responses, and magnitude of PfEMP1 specific anti- body responses between children with uncomplicated malaria (UM) and children with ...
15
Review Article c-Ret-mediated hearing losses
... We thank Yoko Kato and Harumi Ohno for their technical assistance. This study was supported in part by Grants-in-Aid for Scientific Research (B) (No. 19390168 and No. 20406003), Grant- in-Aid for Challenging Exploratory ...
6
Cloning and molecular characterisation of the murine 'c-ret' locus
... In addition to MENIIA (Donis-Keller et al., 1993), MENIIB (Eng et al., 1994; Hofstra et al., 1994) and FMTC (Mulligan et al., 1993), mutations within the c-RET proto oncogene has also been shown to segregate ...
314
Multiple endocrine neoplasia type 2
... the tumor. This test is also of importance to detect and thus, to reduce the risk of an unsuspected PHEO. Moreo- ver, the aggressiveness of MTC correlates with the specific c-RET codon mutation and this strong ...
6
Genetic mutations in the treatment of anaplastic thyroid cancer: a systematic review
... inhibit RET and RET/ PTC (sorafenib, sunitinib, vandetanib) or the mammalian target of rapamycin (mTOR), a component of the PI3K/ Akt signaling pathway ...
6
Pericytes limit tumor cell metastasis
... Previously we observed that neural cell adhesion molecule (NCAM) deficiency in β tumor cells facilitates metastasis into distant organs and local lymph nodes. Here, we show that NCAM-deficient β cell tumors grew leaky ...
11
Somatic RET mutation in a patient with pigmented adrenal pheochromocytoma
... the RET-proto-oncogene are associated with sporadic pheochromocytoma, familial or sporadic medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia type ...
5
Radiation exposure, young age, and female gender are associated with high prevalence of RET PTC1 and RET PTC3 in papillary thyroid cancer: a meta-analysis
... increase RET/PTCrearrangement risk. Accordingly, several studies have detected RET/PTC rearrangements more frequently in PTC in children than in adults [8, ...of RET/PTC rearrangements was reported ...
15
Germline Ret Mutations In Exons 10 And 11: An Iranian Survey Of 57 Medullary Thyroid Carcinoma Cases
... Germline RET Mutations in Exons 10 and 11 An Iranian Survey of 57 Medullary Thyroid Carcinoma Cases ORIGINAL ARTICLE Germline RET Mutations in Exons 10 and 11 An Iranian Survey of 57 Medullary Thyroid[.] ...
6
Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes
... c The bar diagram shows the average (+SD) proportion of young (reticulocytes: RET, filled bars ) and mature (non-reticulocytes: no-RET, empty bars ) PNH (CD59-negative) red cells bound w[r] ...
10
A Drosophila Model of Multiple Endocrine Neoplasia Type 2
... human Ret. (A) Detailed alignment of dRet (top sequence) and human Ret (bottom sequence) kinase domain and C ...human Ret is the PLCg-binding site (B orrello et ...for Ret MEN2A activity, and ...
25