retinal endothelial cells
The Impact of Hyperglycemia on VEGF Secretion in Retinal Endothelial Cells
... monkey retinal endothelial cells (trans- formed) were purchased from American Type Culture Collection (ATCC) (Catalog number: CRL ...revive cells in a T75 fl ask. The cells were stored ...
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Original Article Pterostilbene impact on retinal endothelial cells under high glucose environment
... and retinal endothelial cells oxidation by free radicals is one of its ...human retinal endothelial cells (hRECs) under high glucose environment to illustrate pterostilbene ...
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Polycomb Repressive Complex 2 Regulates miR-200b in Retinal Endothelial Cells: Possible Implications in Diabetic Retinopathy
... metabolically inactive and does not cause oxidative stress and hyperglycemia- induced signaling changes as D-glucose does (91,92). At both 24 and 48 hours, miR-200b levels showed significant decrease in HG compared to NG ...
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Original Article Increased miR-223 expression promotes proliferation and migration of retinal endothelial cells and pathogenesis of diabetic retinopathy by targeting EIF4E3 and IGF-1R
... Apoptosis of transfected RECs was measured using a cyanine dye (Cy5)-labeled annexin V apoptosis detection kit and analyzed by flow cytometry [23]. Briefly, cells were harvested, washed, and pelleted after ...
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Cellular interactions between lymphocytes and retinal endothelial cells
... is thought to be an important molecule in brain inflammatory reactions as mAb to the VLA-4 integrin has been used successfully to prevent experimentally induced inflammation of the CNS in rats (Yednock et al., 1992). ...
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PubMedCentral-PMC5382795.pdf
... in retinal endothelial cells, also dramatically reduced vascular sprouting and density, while loss of ALK2, which is enriched behind the vascular front, did not significantly affect sprouting but ...
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High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy
... microvascular endothelial cell line was obtained from American Type Culture Collection (Manassas, VA, ...HMEC-1 cells were cultured in human endothelial-SFM ...Mouse retinal endothelial ...
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Original Article Endotoxin-induced uveitis promotes retinal endothelial cell injury and Muller cell proliferation
... uveitis. Retinal microvascular endothelial cells and Muller cells are responsible for the supply of retinal neurotrophic ...in retinal endothelial cell injury and Muller ...
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ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells
... from endothelial cells, gain-of-function and loss-of-function experiments were performed using adeno- viruses expressing wild type ATF4 (Ad-ATF4) or its dominant negative form ...mouse retinal ...
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Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells
... the retinal endothelial cells so it is not surprising that it did not increase the expression of PG core proteins sufficiently to be observed as an increase radiosulfate expression (see ...
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Macular Degeneration and the Pharmacology of Lycium Berries
... the retinal vasculature is important in macular degeneration ...to retinal endothelial cells and transmigrate into the macula due to the presence of integrin β1 in early macular degeneration ...
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Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease
... human retinal microvascular endothelial cells, retinal pericytes, and Müller cells as well as retinal pigmented epithelial cells of the OBRB to the PRVABC56 strain of ...
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Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction
... used retinal vasculature to determine the role of circular RNA in vascular ...decreased retinal vessel loss and suppressed pathological angiogenesis in ...increased endothelial cell migration and ...
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Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration
... RPE cells were exposed to several concentrations of H 2 O 2 , there was a selective and greater expression of VEGF 189 than with control conditions, and also compared with the other splice variants (Figure ...
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Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells
... Pathological retinal neovascularization is the foremost destructive manifestation of diabetic ...RF/6A cells in ...against retinal neovasculariza- tion is mediated, in part, through the formation of ...
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Original Article Profilin-1 mediates microvascular endothelial dysfunction in diabetic retinopathy through HIF-1α-dependent pathway
... and cells from passages 3-7 were used in the experiment. Cells were grown in M199 medium with 45 ng/ mL bFGF and heparin and 20% fetal bovine ...Confluent cells were switched to a serum-free medium ...
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Knockout of insulin and IGF 1 receptors on vascular endothelial cells protects against retinal neovascularization
... in retinal neovascu- larization following disruption of insulin receptor in endothelial cells, which is accompanied by suppression of these vascular mediators, further implicates the role of these ...
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CAMKII as a therapeutic target for growth factor–induced retinal and choroidal neovascularization
... pathological retinal angiogenesis in ...in retinal neovascularization (Figure ...the retinal vascular network (Supplemental Figure 2) or in the gross morphology of the retina (Supplemental Figure 3) ...
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Hypoxic Induction of Endothelial Cell Growth Factors in Retinal Cells: Identification and Characterization of Vascular Endothelial Growth Factor (VEGF) as the Mitogen
... fect of hypoxia on the regulation of bFGF, a potent endothelial cell mitogen produced by hRPE, to determine if the induction of VEGF during hypoxia is part of a general cellular re- spon[r] ...
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TRPV4 regulates migration and tube formation of human retinal capillary endothelial cells
... the cells were incubated with specific primary anti- bodies against TRPV4 overnight at 4°C, and then with Alexa Fluor secondary antibodies(Invitrogen, Grand Island, NY, USA) for 2 h at room ...temperature. ...
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