RNA interference and viruses
RNA Interference against Animal Viruses: How Morbilliviruses Generate Extended Diversity To Escape Small Interfering RNA Control
... infections, viruses have become the major threats to human and animal ...of viruses to acquire resistance ...years, RNA interference (RNAi) has been the focus of intensive research because it ...
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Replication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication
... because it is well-established that the HIV-1 Nef gene is dispensible for viral replication in cultured human cells [66,67] The five cellular miRNAs, miR28, miR29b, miR138, miR211, and miR326, were selected because each ...
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RNA Interference in Protozoan Parasites: Achievements and Challenges
... It was recognized early on that RNAi has a widespread role in silencing parasitic nucleic acids, such as those of mobile elements and certain RNA viruses, and thus contributes to the maintenance of genome ...
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Betanodavirus B2 Is an RNA Interference Antagonist That Facilitates Intracellular Viral RNA Accumulation
... Indeed, RNA viruses are widely known to be extremely sensitive to mutation and can be considered as existing on the threshold of error catastrophe ...
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RNA Interference Targets Arbovirus Replication in Culicoides Cells
... These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organ- ...isms. RNA interference (RNAi) is a sequence-specific RNA ...
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Modulation of Flavivirus Population Diversity by RNA Interference
... hosts, RNA viruses exist as a dynamic population of closely related viral variants termed a ...host viruses that establish chronic infections ...borne viruses, such as West Nile virus (WNV ...
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The reverse genetics applied to fish RNA viruses
... of RNA silencing in infected insects, an adap- tive antiviral response that controls viral infection in plants and ...FHV RNA and formation of progeny virus particles are critically dependent on the ...
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Inhibition of Gammaherpesvirus Replication by RNA Interference
... without RNA duplexes ...posttransfection, viruses from cells trans- fected with viral DNA alone or cotransfected with siRNA-K8 showed dissemination to neighboring cells, indicated by GFP expression from the ...
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RNA Interference in Fungi: Pathways, Functions, and Applications
... against viruses and transposons ...invading viruses are also able to quickly move from one cell to another ...viral RNA replication of many viruses, can initiate potent RNAi-mediated gene ...
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Suppression of RNA Interference by Adenovirus Virus-Associated RNA
... mammalian viruses, therapeutic intervention of virus infec- tions by siRNA treatment needs to take this suppressive mech- anism into ...VA RNA might negatively affect the efficiency of adenovirus-delivered ...
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Inhibition of Monkeypox virus replication by RNA interference
... these viruses and no licensed antiviral drug therapy is ...of RNA interference pathway (RNAi) as a therapeutic approach for orthopox virus infections using MPV as a ...small interference ...
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Autoimmune targeting of key components of RNA interference
... the RNA silencing machinery, in particular ...mammalian viruses encode suppressors of RNAi ...that viruses may promote the develop- ment of autoimmunity via their association with components of ...
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An Insight To RNA Interference Based Gene Silencing
... RNA degradation process called post transcriptional gene silencing (PTGS/RNAi) (1). This phenomenon was first observed by Fire and Mello in the year 1998 for which they were awarded Nobel Prize in 2006. The central ...
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Gene-Specific Inhibition of Reovirus Replication by RNA Interference
... RNA interference (RNAi) is a sequence-specific gene-si- lencing mechanism that employs dsRNA to produce short in- terfering RNAs (siRNAs) approximately 21 nucleotides (nt) in length (12, ...as ...
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An antiviral role for the RNA interference machinery in Caenorhabditis elegans
... against viruses, but the hypothesis that ani- mals possess a similar natural antiviral mechanism related to RNAi remains relatively ...to viruses in ...
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Treatment of Ischemia Reperfusion Injury with RNA Interference
... of RNA micro- arrays may help to identify which genes are up regulated and during which phase in the IRI ...stress, RNA degradation, and DNA repair were associated with DGF ...
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Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.
... Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest DNA polymerases purified by the same procedure from four mammalian RNA viruses, simian sarcoma virus type 1, gibbon ape [r] ...
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Inhibition of osteoclastogenesis by RNA interference targeting RANK
... Total RNA was isolated from cultured cells and purified using the RNeasy Mini Kit (Qiagen, Hilden, Germany). The yield and purity of the RNA was controlled photo- metrically. RT-PCR was performed in the ABI ...
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The virion associated incoming HIV 1 RNA genome is not targeted by RNA interference
... viral RNA genome during the initial phase of infection prior to com- pletion of reverse transcription that converts the RNA genome into ...the RNA genome within the virion core is accessible to the ...
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Nyamanini and Midway Viruses Define a Novel Taxon of RNA Viruses in the Order Mononegavirales
... viral RNA which had been reverse transcribed and randomly ...the RNA poly- merases from a number of viruses in the families Bornaviridae, Filoviridae, and Rhabdoviridae, which are all members of the ...
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