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Rna Interference (rnai)

Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes

Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes

... flavivirus RNA (sfRNA) in infected ...conserved RNA structures in the 3= untranslated region (UTR) of the viral genomic ...both RNA interference (RNAi)-competent and -compromised mosquito cell ...

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ESF EMBO Symposium: Antiviral Applications of RNA Interference

ESF EMBO Symposium: Antiviral Applications of RNA Interference

... The first ESF-EMBO symposium on "Applications of anti- viral RNA interference (RNAi)" was held in the spring of 2008 (5–10 april) in Sant Feliu de Guixols at the Costa Brava in Spain. Some 60 ...

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Modulation of Flavivirus Population Diversity by RNA Interference

Modulation of Flavivirus Population Diversity by RNA Interference

... RNA interference (RNAi)-depleted and RNAi-intact S2 cells were sequenced by pyrosequencing. Using the highly sensitive viral variant caller V-phaser (25), we quantified two diversity estimates: the ...

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RNA Interference in Protozoan Parasites: Achievements and Challenges

RNA Interference in Protozoan Parasites: Achievements and Challenges

... RIT-Seq. A giant leap forward in the evolution of RNAi screening technology for trypanosomes was the development in the laboratory of David Horn of the RIT-Seq method (RNA Interference Target Sequencing) ...

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Biotechnology and Plant Disease Control Role of RNA Interference

Biotechnology and Plant Disease Control Role of RNA Interference

... different RNA molecules in the target cells while that in the hpRNA systems is achieved by self-folding of inverted repeats within RNA ...study, RNA interference (RNAi) strategy was used to ...

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Enhancement of RNA Interference Effect in P19 EC Cells by an RNA-dependent RNA Polymerase

Enhancement of RNA Interference Effect in P19 EC Cells by an RNA-dependent RNA Polymerase

... double-stranded RNA (dsRNA) into Caenorhabditis elegans led to an efficient sequence-specific gene silencing, which is referred to as RNA interference ...

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An Insight To RNA Interference Based Gene Silencing

An Insight To RNA Interference Based Gene Silencing

... exploit RNA interference in ...of RNA interference, especially the potential for "off- target" effects in which a gene with a coincidentally similar sequence to the targeted gene is ...

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RNA-Based Immunity Terminates Viral Infection in Adult Drosophila in the Absence of Viral Suppression of RNA Interference: Characterization of Viral Small Interfering RNA Populations in Wild-Type and Mutant Flies

RNA-Based Immunity Terminates Viral Infection in Adult Drosophila in the Absence of Viral Suppression of RNA Interference: Characterization of Viral Small Interfering RNA Populations in Wild-Type and Mutant Flies

... viral RNA genomes in fruit flies and mosquitoes induces the production of virus-derived small interfering RNAs (siRNAs) to specifically reduce virus accumulation by RNA interference ...the ...

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Inhibition of Gammaherpesvirus Replication by RNA Interference

Inhibition of Gammaherpesvirus Replication by RNA Interference

... RNA interference (RNAi) is a mechanism conserved among different species, in which double-stranded RNAs trigger a sequence-specific gene-silencing ...called RNA-induced silencing ...of RNA ...

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RNA Interference Targets Arbovirus Replication in Culicoides Cells

RNA Interference Targets Arbovirus Replication in Culicoides Cells

... isms. RNA interference (RNAi) is a sequence-specific RNA degradation mechanism that has been shown to play a major role in the antiviral response against arboviruses in ...double-stranded RNA ...

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RNA Interference and its application in management of viral   diseases in plants

RNA Interference and its application in management of viral diseases in plants

... the RNA-induced silencing complex ...messenger RNA molecule and induces cleavage by Argonaute, the catalytic component of the RISC ...Historically, RNA interference was known by other names, ...

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Engineering Ligand Control of RNA Interference

Engineering Ligand Control of RNA Interference

... mechanism, RNA interference (RNAi), provided the motivation to pursue the design of riboswitches that exploit this powerful mechanism of control (Sahu et al, 2007; Scherer and Rossi, ...

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RNA Interference: Past, Present and Future

RNA Interference: Past, Present and Future

... RNA interference (RNAi), initially coined by Fire et al., (1998), is the sequence-specific gene silencing induced by double-stranded RNA (dsRNA; Figure 1; Wall and Shi, 2003). This phenomenon has ...

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RNA interference based resistance against a legume mastrevirus

RNA interference based resistance against a legume mastrevirus

... RNA interference (RNAi) is a homology-dependent mechanism that involves the specific degradation of cel- lular RNA by a complex of ...interfering RNA (siRNA) and micro RNA (miRNA)], ...

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RNA Interference: An Evolutionary Pathway in Periodontal Tissue Engineering

RNA Interference: An Evolutionary Pathway in Periodontal Tissue Engineering

... antisense RNA to shut down expression of the par-1 gene in order to assess its ...antisense RNA disrupted expression of par-1, but quizzically, injection of the sense-strand control did too used antisense ...

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Gene-Specific Inhibition of Reovirus Replication by RNA Interference

Gene-Specific Inhibition of Reovirus Replication by RNA Interference

... RNA interference (RNAi) is a sequence-specific gene-si- lencing mechanism that employs dsRNA to produce short in- terfering RNAs (siRNAs) approximately 21 nucleotides (nt) in length (12, ...as ...

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A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression

A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression

... targeted RNA interference (RNAi) screen for cellular chromatin fac- tors that are involved in regulation of herpes simplex virus (HSV) gene expression in U2OS osteosarcoma cells, a cell line that ...

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Inhibition of Monkeypox virus replication by RNA interference

Inhibition of Monkeypox virus replication by RNA interference

... of RNA interference pathway (RNAi) as a therapeutic approach for orthopox virus infections using MPV as a ...small interference RNA ...

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Autoimmune targeting of key components of RNA interference

Autoimmune targeting of key components of RNA interference

... impair RNA interference (RNAi) or RNA silencing ...from RNA viruses [11] or the random integration of transposable elements ...small RNA molecules referred to as microRNAs (miRNAs) did ...

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RNA interference approaches for treatment of HIV-1 infection

RNA interference approaches for treatment of HIV-1 infection

... HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 replication and delay the onset of ...

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