RNA Polymerase I
Autoantibody to RNA polymerase I in scleroderma sera
... anti-RNA polymerase I antibodies stained the same fibrillar structures in drug-segregated nucleoli as scleroderma ...anti-RNA polymerase I antibodies, and their common identities ...
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Human RNA Polymerase I-Driven Reverse Genetics for Influenza A Virus in Canine Cells
... an RNA polymerase I (pol I) promoter to synthe- size negative-sense viral RNA and an RNA pol II promoter to transcribe positive-sense mRNA from one viral cDNA tem- ...
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The Trypanosomatid-Specific N Terminus of RPA2 Is Required for RNA Polymerase I Assembly, Localization, and Function
... use RNA polymerase I (pol I) to transcribe protein-coding ...pol I subunits vary compared to their homologues elsewhere, and the question arises as to how these varia- tions relate to ...
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RNA Polymerase I Transcription Silences Noncoding RNAs at the Ribosomal DNA Locus in Saccharomyces cerevisiae
... Pol I or Pol II transcription, we measured both the 35S RNA synthesis and ncRNA production in a yeast strain (UKY403) where the histone H4 gene is under GAL1 pro- moter control ...Pol I and Pol II ...
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Immunochemical and molecular characterization of anti RNA polymerase I autoantibodies produced by tight skin mouse
... like RNA polymerase I (RNA pol I) are produced in a number of rheumatic autoimmune ...of RNA pol I appears to be characteristic in the patients with systemic ...pol ...
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Nucleosomes Are Depleted at the VSG Expression Site Transcribed by RNA Polymerase I in African Trypanosomes
... eukaryotes, RNA polymerase I (Pol I) exclusively transcribes long arrays of identical rRNA genes (ribosomal DNA ...Pol I to also transcribe the variant surface glycoprotein VSG ...Pol ...
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The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective
... of RNA polymerase I (Pol I) transcriptional ...Pol I activity is continually increased in proliferating cells to sustain the increased demand for ribosome production and protein ...
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RNA Polymerase I-Driven Minigenome System for Ebola Viruses
... an RNA polymerase I (Pol I)-driven minigenome ...Pol I-driven Reston ebolavirus minigenome system provides a higher signal intensity with less background (higher signal-to-noise ratio) ...
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Production of Infectious Hepatitis C Virus by Using RNA Polymerase I-Mediated Transcription
... In the present study we assessed the effects of N-linked glycosylation inhibitors on HCV production using H751JFH1/ Zeo (Fig. 7) and found that an ␣ -glucosidase inhibitor NN- DNJ inhibits the production of infectious ...
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Atypical clinical presentation of a subset of patients with anti RNA polymerase III non scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining
... Case 3: A 57-year-old female, who had a 10-year his- tory of RP, visited a clinic for worsening RP in April 2002, when hydroxychroloquine was started. In May 2002 she was hospitalized elsewhere for dyspnea, hypoxia and a ...
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Efficient generation of influenza virus with a mouse RNA polymerase I driven all in one plasmid
... mouse RNA PolI- driven 8-plasmid system included plasmids pYA4965 (PB1), pYA4966 (PB2), pYA4967 (PA), pYA4968 (NP), pYA4969 (HA), pYA4970 (NA), pYA4971 (M), and pYA4972 ...
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Genetic control of RNA polymerase I-stimulated recombination in yeast.
... The rate of gene replacement but not excisive recombination is stimulated by HOTl in radlA rad52-8 strains.. Taken together, the results show that HOTl stimulates exchang[r] ...
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Mutations affecting RNA polymerase I-stimulated exchange and rDNA recombination in yeast.
... Plasmid constructions and DNA manipulations: DNA manipulations and yeast transformations were conducted as previously described (KEIL and ROEDER 1984; VOELKEL- MEIMAN, KEIL a[r] ...
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The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription
... Normally, BRCA1 is preferentially associated with promoters, 5 ′ UTR’s and exons and significantly underrepresented within introns and intergenic regions [27, 28, 30]. Thus, the BRCA1 distribution profile at rDNA repeat ...
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Role of Second-Largest RNA Polymerase I Subunit Zn-Binding Domain in Enzyme Assembly
... RNAP I also appear to interact, based on genetic-suppression data of Yano and Nomura ...RNAP I, and the rpa135 suppressor mutation restores the complex stability ...
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Identification of autoantibodies to RNA polymerase II Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III
... anti-RNA polymerase II antibodies also immunoprecipitated proteins that were consistent with components of RNA polymerases I and ...of RNA polymerase II ...anti-RNA ...
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De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase
... an RNA hairpin structure, which is required for viral RNA synthesis ...the polymerase for both template and initiation ...template RNA usually results in a severe reduction of viral RNA ...
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Influenza A virus RNA-dependent RNA polymerase: analysis of RNA synthesis in vitro.
... three polymerase subunits and NP have been shown to be sufficient to carry out all the enzymatic functions necessary for replication of the genome (6, 13, 16, 25, ...of polymerase functions. The biochemical ...
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RNA Polymerase Transcription Machinery in Trypanosomes
... with RNA pol II (see ...initiate RNA synthesis at a specific ...of RNA pol II at gene promoters ...SL RNA gene pro- moter, the only described RNA pol II-dependent promoter in ...
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Biochemical characterization of the fidelity of poliovirus RNA dependent RNA polymerase
... render RNA viral diseases partic- ularly intractable are rapid emergence of drug resistance, vaccine escape and emergence of novel ...of RNA viruses are thought to be mediated by "quasi-species" ...
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