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RNA viruses

Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

... negative-strand RNA viruses, however, we were unable to detect dsRNA in infected ...positive-strand RNA virus EMCV but not to the negative-strand RNA virus Sendai virus ...negative-strand ...

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Clinical Impact of Apparent Structural and Functional Similarities between Extracellular Vesicles RNA (EVs RNA) and Chronic RNA Viruses

Clinical Impact of Apparent Structural and Functional Similarities between Extracellular Vesicles RNA (EVs RNA) and Chronic RNA Viruses

... chronic RNA viruses (e.g. HCV, Herpes viruses and HIV) which may exert relatively harmless effect and remain dormant within the human body for months and ...

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Extensive Diversity of RNA Viruses in Australian Ticks

Extensive Diversity of RNA Viruses in Australian Ticks

... Negative-sense RNA viruses. The complete coding region of seven ⫺ ssRNA viruses were identified within 4 of the 11 libraries produced in this ...these viruses fell within the Phenuiviridae and ...

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RNA Viruses in Blechomonas (Trypanosomatidae) and Evolution of Leishmaniavirus

RNA Viruses in Blechomonas (Trypanosomatidae) and Evolution of Leishmaniavirus

... the viruses and the species of flagellates or their primary/secondary hosts was apparent from the data (Table 1; ...these viruses shared a characteristic tripartite genome arrangement. Their ...

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The reverse genetics applied to fish RNA viruses

The reverse genetics applied to fish RNA viruses

... VHSV viruses. It is well known that RNA viruses sustain mutations at a frequency of approximately of 10 -4 mutations per nucleotide copied, which is almost equiva- lent to one mutation per ...

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Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

... on RNA 1 (ADAR1) is a double-stranded RNA binding protein and RNA-editing enzyme that modifies cellular and viral RNAs, including coding and noncoding ...mechanisms: RNA editing and inhibition ...

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Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

... large-scale RNA structure and host persistence. The RNA secondary structure, calculated as the probability of the internal base pairing of individual bases in an RNA molecule, has been shown to be an ...

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Interactions between the Structural Domains of the RNA Replication Proteins of Plant-Infecting RNA Viruses

Interactions between the Structural Domains of the RNA Replication Proteins of Plant-Infecting RNA Viruses

... FIG. 5. Summary of the predicted secondary structures of BMV and related 1a proteins. Boxes, a-helices; arrows, b-sheets; solid shapes, .80% accuracy; open shapes, .50% accuracy. (A) Diagram of the BMV 1a protein and its ...

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Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion

Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion

... of RNA viruses, including viral double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), and surface glycopro- ...of RNA viruses known to be targets of TLR ...

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Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

... viral RNA populations is that the low fidelity of the RNA-dependent RNA polymerase (RdRp) drives high mu- tation rates and consequently genetic ...most RNA viruses, wild-type yel- low ...

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Double-Stranded RNA Is Detected by Immunofluorescence Analysis in RNA and DNA Virus Infections, Including Those by Negative-Stranded RNA Viruses

Double-Stranded RNA Is Detected by Immunofluorescence Analysis in RNA and DNA Virus Infections, Including Those by Negative-Stranded RNA Viruses

... by viruses that block dsRNA exposure (27–30), yet in a study by Weber et ...negative-strand RNA virus infec- tions for detection by immunofluorescence ...strand RNA virus infections, the use of the ...

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Diverse roles and interactions of RNA structures during the replication of positive-stranded RNA viruses of humans and animals

Diverse roles and interactions of RNA structures during the replication of positive-stranded RNA viruses of humans and animals

... viral RNA functions is becoming increasingly ...many RNA structures do not function as discrete elements but through mechanisms involving multiple, long-range and often dynamic RNA-RNA ...

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Predicting broad-spectrum antiviral drugs against RNA viruses using transcriptional responses to exogenous RNA

Predicting broad-spectrum antiviral drugs against RNA viruses using transcriptional responses to exogenous RNA

... transcriptional responses to the delivery of cas9 mRNA into human hematopoietic stem and progenitor cells (HSPCs) highly matches those triggered by small molecules with broad-spectrum antiviral activity such as emetine, ...

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Existing Host Range Mutations Constrain Further Emergence of RNA Viruses

Existing Host Range Mutations Constrain Further Emergence of RNA Viruses

... ABSTRACT RNA viruses are capable of rapid host shifting, typically due to a point mutation that confers expanded host ...double-stranded RNA (dsRNA) bacteriophage ␸ 6 (wild type and two isogenic host ...

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Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses

... diverse RNA viruses. To deter- mine the diversity of viruses that are impacted by polyamine de- pletion, we examined whether DFMO pretreatment of cells could limit the replication of the ...

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How Positive-Strand RNA Viruses Benefit from Autophagosome Maturation

How Positive-Strand RNA Viruses Benefit from Autophagosome Maturation

... many viruses avoid or suppress host immune responses, several subvert the host immune machinery to promote their own replication ...positive-strand RNA viruses, which are the causative agents of many ...

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Nyamanini and Midway Viruses Define a Novel Taxon of RNA Viruses in the Order Mononegavirales

Nyamanini and Midway Viruses Define a Novel Taxon of RNA Viruses in the Order Mononegavirales

... viral RNA which had been reverse transcribed and randomly ...the RNA poly- merases from a number of viruses in the families Bornaviridae, Filoviridae, and Rhabdoviridae, which are all members of the ...

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Is the Quasispecies Concept Relevant to RNA Viruses?

Is the Quasispecies Concept Relevant to RNA Viruses?

... in RNA viruses occurred with laboratory populations of Q␤ phage where an equilibrium distribution of closely related mutants was observed, with a stable consensus sequence maintained throughout passage ...

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Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.

Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.

... Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest DNA polymerases purified by the same procedure from four mammalian RNA viruses, simian sarcoma virus type 1, gibbon ape [r] ...

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Molecular Basis of Adaptive Convergence in Experimental Populations of RNA Viruses

Molecular Basis of Adaptive Convergence in Experimental Populations of RNA Viruses

... evolution. The quasi-species model differs from the clas- 0.6128, 19 d.f., one-tailed P ⫽ 0.0016), confirming the sical population genetics models in that neutral muta- prediction made by the clonal interference model. ...

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