S. aureus protein A
Fibrinogen is a ligand for the S aureus MSCRAMM Bbp (Bone sialoprotein binding protein)
... MSCRAMMs (microbial surface components recognizing adhesive matrix molecules) are bacterial surface proteins mediating adherence of the microbes to components of the extracellular matrix of the host. On Staphylococci the ...
19
Molecular Characterization of the Multiple Interactions of SpsD, a Surface Protein from Staphylococcus pseudintermedius, with Host Extracellular Matrix Proteins
... Staphylococcus pseudintermedius, a commensal and pathogen of dogs and occasionally of humans, expresses surface proteins potentially involved in host colonization and pathogenesis. Here, we describe the cloning and ...
12
The relationship between S. aureus and branched-
... persist. S. aureus requires branched-chain amino acids (BCAAs: isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acids synthesis and environmental adaptation by responding to ...
14
Staphylococcus aureus Fibronectin Binding Protein A Mediates Cell Cell Adhesion through Low Affinity Homophilic Bonds
... ure 6A to C (see Fig. S3 for more cells) shows that a large fraction (~50%) of the force curves recorded across three different cells featured single adhesion peaks with a moderate force of 125 ⫾ 65 pN (mean ⫾ SD from a ...
10
Protein A mediated multicellular behavior in Staphylococcus aureus
... of protein A in staphylococcal virulence. Protein A-defective mutants show reduced virulence in murine models of septic arthritis, septi- cemia, and skin abscesses, most likely due to the antiphagocytic ...
12
The Staphylococcus aureus “superbug”
... inhibitory protein and staphylokinase ...The S. aureus population is clonal The study by Melles et ...of S. aureus con- cerning clonality and ...829 S. aureus strains from ...
5
Protein A Suppresses Immune Responses during Staphylococcus aureus Bloodstream Infection in Guinea Pigs
... purified protein emulsified in CFA (Difco) and boosted with 50 g of protein emulsified in IFA (Difco) 11 days following the first ...of protein adsorbed to alumi- num hydroxide (Alhydrogel “85”; ...
11
Insilico structure prediction of saer protein from staphylococcus aureus
... Bacterial infections are usually a consequence of successful colonization of the host as well as breaching the host’s immune defence- system. Gram positive bacterial infections account for ~50% of all reported sepsis and ...
5
A human endothelial cell membrane protein that binds Staphylococcus aureus in vitro
... investigated S. aureus adherence to human endothelial cells utilizing an in vitro ...binds S. aureus, in ...the protein was synthesized by and expressed on the endothelial cell ...the ...
8
Antibiotic potential of phytochemicals in Punica granatum pericarp and their proposed mechanism of action by in silico studies
... topoisomerase-IV protein with a free binding energy of ...of S. aureus and MRSA ...This protein-ligand docking analysis provides a preliminary ...
8
DETECTION OF METHICILLIN RESISTANCE GENE IN S. AUREUS BY PCR
... expresses protein called altered penicillin binding protein (PBP ...this protein is changed, the β –lactam antibiotic cannot prevent cell wall formation and hence the resistance to the antibiotic is ...
5
Binding of Staphylococcus aureus Protein A to von Willebrand Factor Is Regulated by Mechanical Force
... SpA mediates bacterial adhesion to immobilized vWF through specific bonds that are much stronger ( ⬃ 2 nN) than most receptor-ligand interactions studied to date. Compared to its soluble form, immobilized vWF is ...
13
Staphylococcus aureus Protein A Mediates Interspecies Interactions at the Cell Surface of Pseudomonas aeruginosa
... Staphylococcus aureus frequently coinfects with other pathogens in a range of different infectious ...by S. aureus with Pseudomonas aerugi- nosa occurs commonly in people with cystic fibrosis and is ...
9
Mechanical Strength and Inhibition of the Staphylococcus aureus Collagen Binding Protein Cna
... ated as described by Köhler and Milstein (39) with minor modifications and produced essentially as reported in reference 14. Briefly, BALB/c mice were injected intraperitoneally five times at 1-week intervals with 50 g ...
11
Cross Sectional Study of Skin Carriage and Enterotoxigenicity of Staphylococcus aureus among Food Handlers
... Staphylococcus aureus (bioMerieux Marcy— I’Etoile, ...of protein A and clumping factor using SLIDEX Staph plus (bioMerieux Marcy—I’Etoile, ...of S. aureus NCTC 10788 (obtained from food ...
7
Lack of microbiological concordance between bone and non bone specimens in chronic osteomyelitis: an observational study
... Three patients with history and images of COM had sterile bone cultures, one also had sterile non-bone cultures. Two of them were on antibiotics before specimen sam- pling. Prospective following with aerobic and ...
7
Occurrence of clinical mastitis in primiparous Estonian dairy cows in different housing conditions
... Results: Clinical mastitis occurrence in the study population of freshly calved heifers equalled 6.1 %. Housing system was not a significant risk factor for clinical mastitis of freshly calved heifers. Moving heifers to ...
6
New Quadriplex PCR Assay for Detection of Methicillin and Mupirocin Resistance and Simultaneous Discrimination of Staphylococcus aureus from Coagulase Negative Staphylococci
... Staphylococcus aureus, in par- ticular, is a leading cause of diseases ranging from mild skin and soft tissue infections to life-threatening illnesses, such as deep postsurgical infections, septicemia, and toxic ...
9
CAPSULAR TYPING OF COAGULASE POSITIVE (COPS) COMMUNITY ASSOCIATED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (CA-MRSA) ISOLATED FROM ANTERIOR NARES OF SCHOOL CHILDREN FROM LUSHOTO, KOROGWE, MUHEZA AND TANGA DISTRICTS IN TANZANIA
... Staphylococcus aureus ATCC- 25923 of known coagulase production was included as control ...Staphylococcus aureus by morphological and biochemical studies such as microscopic examination, Gram’s staining, ...
6
Effect of Protein A on Adsorption of Bacteriophages to Staphylococcus aureus
... When adsorption experiments were performed with pleiotropic mutants of Cowan I Class VIE MO; with a combined loss of protein A, nuclease, coagulase and mannitol fermentation, and loss of[r] ...
5