Sample size calculations using main study data
Sample size calculations and normalization methods for RNA-seq data.
... RNA-seq data. These two sample size methods based on a two-sided Wald’s test are presented under a wide range of settings including the imbalanced design and unequal read depth, which is applicable ...
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Sample size calculations for skewed distributions
... Sample size calculations estimate the required number of patients to meet a study ’ s ...subsequent data will affect the actual power, although this dependence is often ignored in ...
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Statistics review 4: Sample size calculations
... large sample size to detect such a difference in mortality with any ...published study had only approxi- mately 13% power to detect a difference of this size using a cutoff for ...
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Discrimination-based sample size calculations for multivariable prognostic models for time-to-event data
... basing sample size on the significance of numerous individual variables is likely to be an intractable ...cited sample size recommendation is the rule of ‘10 events per variable’ (EPV) which ...
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Sample Size Calculations for Population Size Estimation Studies Using Multiplier Methods With Respondent Driven Sampling Surveys
... However, for the SMM this approach needs to be balanced against the potential for recall bias on estimation of P. It is also possible that the relationship between M and the reference period will differ across service ...
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Sample Size Calculations for Population Size Estimation Studies Using Multiplier Methods With Respondent Driven Sampling Surveys
... population size estimation study of 9 communities in Zimbabwe, we found evidence of high homophily by program attendance for some sites but not all ...
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Sample Size Calculations for Population Size Estimation Studies Using Multiplier Methods With Respondent-Driven Sampling Surveys.
... large sample sizes, 95% CIs around the PSE are ...service data, a longer reference period could lead to a higher likelihood of duplicate identification numbers, which would bias the ...
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A multivariate approach to sample size calculations for thorough QT studies
... QT study on any non antiarrythmic drug to ensure that the drug does not produce a QT prolongation effect before it can be approved and ...QT study is substantial and an adverse outcome of the study ...
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Power and Sample Size Calculations for Interval-Censored Survival Analysis
... In addition, we need to provide a weight for each record to reflect the probability of such occurrence, with the weight calculated from the parameters specified for the survival and censoring distributions. The weights ...
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Sample size and power calculations for detecting changes in malaria transmission using antibody seroconversion rate
... analyse data from different study ...Brazilian study where there is evidence for a common change point for ...corresponding data Table 6 Expected bias and precision (in percentage) of ...
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Sample size calculations for cluster randomised trials, with a focus on ordinal outcomes.
... of sample size calculations. Using PubMed I retrieved all articles published in Statistics and Medicine from 1982 to March 2011 and included reference to clustered data or cluster ...
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Sample size calculations in pediatric clinical trials conducted in an ICU: a systematic review
... a sample size calculation is performed, the value of the NP used corresponds to its assumed population ...on data from earlier trials or other types of studies, or conduct a pilot ...
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Bayesian average error based approach to sample size calculations for hypothesis testing
... the study was not powered on these secondary safety ...first study is aimed at investigating if children treated with rosuvastatin (20mg dose) are at higher risk for adverse events compared to a placebo ...
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Sample size calculations for controlling the distribution of false discovery proportion in microarray experiments
... for sample size calculation to control the distributions of FDP and true positives simultaneously under blockwise correlation structures among ...blocks using historical data ...demonstrated ...
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Sample size calculations for cluster randomised controlled trials with a fixed number of clusters
... fixed size, that is with a fixed number of clusters, each of a fixed size (although this size may vary between clusters), then it is possible to evaluate both the detect- able difference and the ...
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Clinical trials of multiple sclerosis monitored with enhanced MRI: new sample size calculations based on large data sets
... power calculations were based on data from small samples of patients with MS, 5–9 and, as a consequence, they were relatively unreliable 9 and potentially ...MRI data sets coming from the placebo ...
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Sample size calculations for crossover thorough QT studies: Non-inferiority and assay sensitivity
... QT/QTc study’ is substantial and an adverse outcome of the study can be detrimental to the safety profile of the drug, hence sample size calculations play a very important role in ...
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Practical help for specifying the target difference in sample size calculations for RCTs : the DELTA2 five-stage study, including a workshop
... the sample size if a larger treatment difference is anticipated or hoped ...final sample size can depend on the observed interim ...the study to ensure that statistical power is ...
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Practical help for specifying the target difference in sample size calculations for RCTs : The DELTA2 five-stage study, including a workshop
... the sample size if a larger treatment difference is anticipated or hoped ...final sample size can depend on the observed interim ...the study to ensure that statistical power is ...
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Sample Size Calculation For Longitudinal Cohort Study
... cohort study is always greater than when those assumptions are exposed and the ...the sample size calculation for cohort study is maximum power in most cases? Gain in repeated the ...
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