Serotonin Transporter
Serotonin Transporter Role in Identifying Similarities Between SIDS and Idiopathic ALTE
... L/L serotonin transporter (5HTT) genotype and correlated genes monoamine oxidase A (MAOA) and dopamine transporter (DAT) in unexpected death, an investigation was carried out verifying their ...
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Child Maltreatment Influences Methylation Density of Serotonin Transporter Gene (5HTTLPR) Depending on Genotype
... However, some meta-analyses have not supported the interaction effect of the short variant of the serotonin transporter and environmental adversity (Munafò, Durrant, Lewis & Flint, 2009; Risch et al., ...
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Correlation between Serotonin Transporter Promoter Gene Polymorphism and PTSD in Children
... [10] Xie, P., Kranzler, H.R., Poling, J., Stein, M.B., et al . (2009) Interactive Effect of Stressful Life Events and the Serotonin Transporter 5-HTTLPR Genotype on Post- traumatic Stress Disorder Diagnosis ...
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Evaluation of the 5 HTTLPR and 5 HTTVNTR Polymorphisms in the Serotonin Transporter Gene in Women with Postpartum Depression
... The serotonin transporter (SERT) is lo- cated in the presynaptic membrane of serotonergic neu- rons, where it controls the intensity and duration of sero- tonergic signaling through the re-uptake of 5-HT in ...
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The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in Idiopathic Trigeminal Neuralgia patients
... The serotonin transporter gene (5-HTT)-linked polymorphic region (5-HTTLPR) plays an important role in regulating 5-HTT expression and thereby controlling the concentration of serotonin (5-HT) in ...
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Polymorphisms of serotonin transporter gene and psychological status in patients with multiple sclerosis
... The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat ...
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INFLUENCE OF SEROTONIN TRANSPORTER-LINKED POLYMORPHIC REGION (5-HTTLPR) VARAINTS ON CLINICAL OUTCOMES IN THAI PATIENTS WITH DEPRESSIVE DISORDER
... the serotonin transporter polymorphisms and clinical outcome of fluoxetine was ...of serotonin receptor and polymorphisms of CYP2D6 synergistically predicted fluvoxamine-induced side effects in 100 ...
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Altered inflammatory responsiveness in serotonin transporter mutant rats
... Serotonin transporter knockout rats (Slc6a4 1Hubr ) were generated in a Wistar background by N-ethyl-N-nitrosurea (ENU)-induced mutagenesis [34]. Experimental animals were derived from crossing heterozygous ...
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DNA methylation of the serotonin transporter gene in peripheral cells and stress related changes in hippocampal volume: A study in depressed patients and healthy controls
... depression. Serotonin is also crucial for brain ...the serotonin system affect brain development and emotion regulation in later ...the serotonin system through epigenetic processes by altering ...
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Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder
... the serotonin transporter gene linked polymorphic region (5-HTTLPR) is associated with risk for ...the serotonin transporter gene were associated with PTSD, but only in the setting of high ...
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Molecular and functional characterization of the Gulf toadfish serotonin transporter SLC6A4
... In addition to its existence in the brain, the presence of SERT transcript in all 13 peripheral tissues examined highlights the ubiquity of the transporter and is consistent with the widespread peripheral ...
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Interactions between integrin αIIbβ3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans
... the transporter (14, 15), suggesting that mul- tiple pathways may interact to affect trans- porter function and ...the transporter, is responsible for SERT catalytic ...
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Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice
... Additional file 1: Figure S1. Additional activity, anxiety-like, and social behavior measures in male B6 SERT Ala56 knock-in mice. A) Distance traveled (mean, standard error of the mean)[r] ...
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A review of the serotonin transporter and prenatal cortisol in the development of autism spectrum disorders
... store serotonin in vesicles where it is released in response to local stimuli ...tissue serotonin levels was demonstrated in SERT-deficient mice, where platelets and most periph- eral organs were found to ...
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Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function
... The GI impact of developmental administration of a SERT inhibitor persisted into adult life, long after the inhibitor was withdrawn. Depression occurs in up to 23% of pregnant women, and SERT inhibition is a common ...
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The interaction of parenting and the serotonin transporter gene on trajectories of fearfulness in early childhood
... Visual depiction of the interaction of fathers’ supportive parenting and children’s 5-HTTLPR genotype on trajectories of shyness from age 3 to age 5 at 1 SD above and below the mean on [r] ...
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Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse
... Abstract: Serotonin (5-hydroxytryptamine [5-HT]) is an important neurotransmitter implicated in regulating substance-use disorder (SUD) acquisition, maintenance, and ...5-HT transporter-linked poly- morphic ...
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Beneficial effects of trimetazidine on expression of serotonin and serotonin transporter in rats with myocardial infarction and depression
... mechanism: serotonin-mediated platelet ...of serotonin concentration, such a connection, if properly elucidated, would seem to promise substantial trans- lational potential for the clinical treatment of ...
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Alteration of serotonin transporter density and activity in fibromyalgia
... Fibromyalgia syndrome (FMs) is a chronic pain syndrome char- acterized by widespread pain and stiffness, multiple tender points, and fatigue [1]. This pain syndrome has an incidence of 2% in the general population and ...
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Impulsivity, gender, and the platelet serotonin transporter in healthy subjects
... Abstract: The present study explored the possible relationships between impulsivity, gender, and a peripheral serotonergic marker, the platelet serotonin (5-HT) transporter (SERT), in a group of 32 healthy ...
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