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Severe Malaria

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

... groups: malaria patients, patients with other infections and a village ...population. Malaria patients were divided into sub-groups based on severity of the disease and dis- ease ...with severe ...

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Clinical review: Severe malaria

Clinical review: Severe malaria

... Cerebral malaria is the most common clinical presentation and cause of death in adults with severe ...cerebral malaria requires the presence of ...cerebral malaria from transient postictal ...

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Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia

Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia

... uncomplicated malaria (UM) phenotype and 288 patients with severe malaria ...cerebral malaria (CM), which justified the separation into two distinct groups, such as CM (n = 130) and ...

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The fluid management of adults with severe malaria

The fluid management of adults with severe malaria

... falciparum malaria, a dis- ease with a unique pathophysiology, it is hazardous and fails to address the microvascular obstruction seen in the ...with severe malaria, clinicians caring for patients ...

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Severe malaria in Canada, 2001–2013

Severe malaria in Canada, 2001–2013

... of malaria treatment procedures and outcomes, complications or adverse effects was not ...IV malaria ther- apies in Canada provided through the ...of severe malaria with other treatments was ...

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Prognosis of Acute Renal Failure of the Child during Severe Malaria in Niamey Niger

Prognosis of Acute Renal Failure of the Child during Severe Malaria in Niamey Niger

... μmol/l). Severe forms of malaria have been defined ac- cording to the WHO Malaria Severity Criteria 2012 ...The severe forms of ma- laria are: severe neurological form (severe ...

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Optimal treatments for severe malaria and the threat posed by artemisinin resistance

Optimal treatments for severe malaria and the threat posed by artemisinin resistance

... We assumed that severe malaria pathology is caused by a sin- gle clone (discussed in Supplementary Information) and simu- lated a monoclonal infection. As previously described [22], we separated the ...

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Haemoglobinuria among children with severe malaria attending tertiary care in Ibadan, Nigeria

Haemoglobinuria among children with severe malaria attending tertiary care in Ibadan, Nigeria

... Results: It was found that the incidence of haemoglobinuria among children with severe malaria is 19.1%. Children <5 years constituted 76.8% of all the study patients. Patients with haemoglobinuria had ...

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Imported Plasmodium vivax malaria with severe thrombocytopaenia: can it be severe malaria or not?

Imported Plasmodium vivax malaria with severe thrombocytopaenia: can it be severe malaria or not?

... d-dimer concentration (9376 ng/dL), the other coagula- tion parameters were within the normal range. Hypona- tremia (127 mmol/L) was present as well as raised values of C reactive protein (126 mg/L), total bilirubin (3.3  ...

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Adjunctive therapy for severe malaria: a review and critical appraisal

Adjunctive therapy for severe malaria: a review and critical appraisal

... in severe malaria treatment The host immune response plays a central role in the onset, severity and outcome of malaria infections and this has promoted the search for immunomodulatory adjunctive ...

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Cytoadherence and Severe Malaria

Cytoadherence and Severe Malaria

... falciparum malaria has become increasingly refractory to chloroquine (21,22), the cheapest and most widely available antimalarial, and this emergence of drug resistance in Southeast Asia and Africa was closely ...

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“I feel so bad but have nothing to do ” Exploring Ugandan caregivers’ experiences of parenting a child with severe malaria and subsequent repeated uncomplicated malaria

“I feel so bad but have nothing to do ” Exploring Ugandan caregivers’ experiences of parenting a child with severe malaria and subsequent repeated uncomplicated malaria

... presumed malaria, caregivers reported challenges in lack of knowledge in administering appropriate malaria treatment for their children and financial medical constraints in managing negative malaria ...

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Role of serum circulatory ige and tnf α level and interleukin 4   590c/t polymorphism in sudanese children with severe falciparum malaria

Role of serum circulatory ige and tnf α level and interleukin 4 590c/t polymorphism in sudanese children with severe falciparum malaria

... in severe malarial anaemia patients in compared to uncomplicated, cerebral malaria and control groups, this results is contrary with Verra et ...cerebral malaria compared to uncomplicated ...

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Malaria: severe, life-threatening

Malaria: severe, life-threatening

... with severe malaria in Sudan, 40 analysed) compared intramuscular artemether ...cerebral malaria) compared intramuscular artemether versus in- travenous ...with severe malaria in India) ...

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Impact of home based management on malaria outcome in under fives presenting in a tertiary health institution in Nigeria

Impact of home based management on malaria outcome in under fives presenting in a tertiary health institution in Nigeria

... of malaria burden, its impact on malaria morbidity and mortality in Africa had shown some contradictory results ...on malaria morbid- ity and mortality in two separate works in Kenya and The Gambia ...

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Copeptin does not accurately predict disease severity in imported malaria

Copeptin does not accurately predict disease severity in imported malaria

... for severe malaria was ...with severe bacterial sepsis [3] and severe leptospirosis [4], copeptin was not found to be a more accurate marker to predict severe disease in malaria ...

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Levels of human proteins in plasma associated with acute paediatric malaria

Levels of human proteins in plasma associated with acute paediatric malaria

... Multivariate analysis was used to identify patterns in the data and to identify a potential combination of markers with higher separation power. Classification of protein level profiles was made using the unsupervised ...

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Invasive bacterial co-infection in African children with Plasmodium falciparum malaria: a systematic review

Invasive bacterial co-infection in African children with Plasmodium falciparum malaria: a systematic review

... with severe malaria over the period 1992 to 2010 from 15 centers in 11 sSA ...of severe malaria, including one randomized controlled trial, whereas two only included children with cerebral ...

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Severe falciparum malaria in Gabonese children: clinical and laboratory features

Severe falciparum malaria in Gabonese children: clinical and laboratory features

... on severe malaria [3- ...of severe malaria were in children less than 5 years ...for malaria in Gabon [19]. Elsewhere, severe malaria tends to occur in older children ...

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Plasmodium vivax severe imported malaria in two migrants in France

Plasmodium vivax severe imported malaria in two migrants in France

... vivax severe malaria [7, 11, ...plicated malaria episode was ...for severe forms of malaria include hyperbilirubinaemia with a threshold > 50 μmol/L [13, ...imported severe ...

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