Sex hormone-binding globulin
Sex hormone binding globulin as a valuable biochemical marker in predicting gestational diabetes mellitus
... AJ. Sex hormone-binding globulin concentrations before conception as a predictor for gestational diabetes in women with polycystic ovary ...
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Correlation between the Sex Hormone Binding Globulin Level and level of Insulin Resistance in Obese Prepubertal Children
... Thus a relationship between hyperinsulinemia and decreased serum sex hormone binding globulin has been described in adults. Felix Gascon et al 54 evaluated usefulness of SHBG as an index of ...
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Common genetic variants in the sex hormone-binding globulin (SHBG) gene in idiopathic recurrent pregnancy loss: a case control study
... steroid sex hormones, in which circulating androgens and estro- gens bind albumin and sex hormone binding globulin (SHBG), resulting in limited amounts of non-bound sex hormones, ...
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Monosaccharide induced lipogenesis regulates the human hepatic sex hormone–binding globulin gene
... The liver produces plasma sex hormone–binding globulin (SHBG), which transports sex steroids and regu- lates their access to tissues. In overweight children and adults, low plasma SHBG ...
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The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial
... and sex hormone ...2 Sex hormone-binding globulin and endogenous sex hormones by treatment group at week 4 and week 8 in ...
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Inverse Relationship between Hepatic Steatosis and Alanine Aminotransferase with Sex Hormone Binding Globulin in Men
... Purpose: Sex hormone-binding globulin (SHBG) is a serum glycoprotein produced predominantly in hepatocytes. As such, the synthesis of SHBG could be associated with liver function and metabolic ...
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SEX HORMONE BINDING GLOBULIN GENE POLYMORPHISM AND RISK OF TYPE2 DIABETES MELLITUS IN EGYPTIAN MEN
... normal sex steroid physiology could play a role in the pathogenesis of type 2 diabetes ...(T2DM). Sex hormone binding globulin gene polymorphisms may be the cause of sex steroid ...
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Human sex hormone–binding globulin variants associated with hyperandrogenism and ovarian dysfunction
... Human sex hormone–binding globulin (SHBG) trans- ports testosterone and estradiol in the blood (1, ...these sex steroids and their access to target tissues (3), and their meas- urements ...
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Sex Hormone Binding Globulin as a Predictor of in Vitro Fertilization Outcomes in Polycystic Ovary Syndrome: Our Results
... Objectives: in case of Polycystic Ovary Syndrome (SOPK), predicting ovarian response before un- dertaking risky in vitro fertilization (IVF) proceeds is crucial. Sex Hormone Binding Globulin ...
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Original Article Association between sex hormone binding globulin gene polymorphism and type 2 diabetes mellitus
... Abstract: This study aims to investigate the relationship between single nucleotide polymorphisms (SNPs) of sex hormone binding globulin (SHBG) and type 2 diabetes mellitus (T2DM) in an Uighur ...
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Association between sex hormone-binding globulin levels and activated protein C resistance in explaining the risk of thrombosis in users of oral contraceptives containing different progestogens
... BACKGROUND: Epidemiological studies have shown that both the estrogen dose and progestogen type of oral contraceptives contribute to the increased risk of thrombosis in oral contraceptive users. Thrombin generation- ...
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Gender-specific associations of serum sex hormone-binding globulin with features of metabolic syndrome in children
... predominant in boys [34]. Moreover, in a cross-sec- tional study performed by Garces and colleagues includ- ing pubertal children (age: 12–15 years), a significantly higher SHBG level was demonstrated in girls than boys, ...
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Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults
... Nuclear receptor hepatocyte nuclear factor 4-α (HNF4α) activates the promoters of multiple genes expressed in he- patocytes that play a role in lipoprotein metabolism [24]. The proximal promoter of the SHBG gene contains ...
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Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study
... In contrast, after multivariable adjustment for known risk factors, total testosterone levels were inversely asso- ciated with diabetes among men (OR, 0.44 [95% CI, 0.23–0.84]), whereas a strong positive relation was ...
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Regulation of sex hormone binding globulin and insulin-like growth factor binding protein-1
... IGF binding (Hardouin et ...IGF binding (Brinkman et ...allow binding of the protein to the cell surface and this may enable IGFBPl to facilitate the transport of IGF-1 to its ...
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The association of sex hormone binding globulin with mortality is mediated by age and testosterone in men with type 2 diabetes.
... by sex hormones and influenced by other hormonal and non- hormonal factors including drugs such as statins [Rosner et ...the hormone thereby reducing its free ...free hormone and the one most ...
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Role of sex hormone binding globulin as the early predictor for gestational diabetes mellitus
... March 2019 Volume 8 Issue 3 Page 967 International Journal of Reproduction, Contraception, Obstetrics and Gynecology Sujatha MS et al Int J Reprod Contracept Obstet Gynecol 2019 Mar;8(3) 967 973 www i[.] ...
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A Study on Insulin Resistance and Obesity Among Women at High Risk for Breast Cancer Using Cluster Analysis.
... of sex- hormone-binding globulin (SHBG) in the blood, which would increase the levels of bioavailable estrogens that can diffuse into endometrial ...
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Review Article First-trimester biomarkers for early prediction of gestational diabetes mellitus: a meta-analysis
... Abstract: Gestational diabetes mellitus (GDM) occurs in approximately 7% of all pregnant women. In order to mini- mize the risk of GDM-associated complications, it is still very important to identify novel biomarkers for ...
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Early Puberty-Menarche After Precocious Pubarche: Relation to Prenatal Growth
... circulating sex hormone– binding globulin and body height were reduced in PP girls with lower birth weight, and these remained so throughout pubertal ...
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