Short peptide
Mechanism of HIV-1 Resistance to Short-Peptide Fusion Inhibitors Targeting the Gp41 Pocket
... for peptide HIV-1 fusion inhibitors, including reduced contact, steric ob- struction, electrostatic repulsion, and electrostatic attraction ...a short-peptide inhibitor and the NHR target, resulting ...
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A short peptide eluted from the H-2Kb molecule of a polyomavirus-positive tumor corresponds to polyomavirus large T antigen peptide at amino acids 578 to 585 and induces polyomavirus-specific immunity.
... A short peptide in complex with the H-2K b molecule on PyRMA, a polyomavirus transfectant of the mouse lymphoma cell line RMA, was identified as a polyomavirus tumor-specific transplantation ...The ...
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Nanomaterials enhance osteogenic differentiation of human mesenchymal stem cells similar to a short peptide of BMP-7
... Osteoinductive biomaterials could stimulate stem cells to differentiate towards the osteogenic pathway. Both alkaline phosphatase activity and calcium deposition were important factors to determine the osteogenic ...
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Redirecting Retroviral Tropism by Insertion of Short, Nondisruptive Peptide Ligands into Envelope
... A potentially powerful approach for in vivo gene delivery is to target retrovirus to specific cells through interactions between cell surface receptors and appropriately modified viral envelope proteins. Previously, ...
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Solving Molecular Recognition Problems with Evolvable Peptide Motifs
... Gs-binding peptide (GSP), was then evolved a step further into matured GSP (mGSP) sequences, which bind specifically to ...relatively short peptide sequences can distinguish very similar G ...
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Structural analysis of leader peptide binding enables leader free cyanobactin processing
... other short peptide substrates with seven, eight or nine core peptide residues including one with three cysteines (Supplementary Figure ...simple, short, linear peptide is a desirable ...
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A multipeptide vaccine plus toll-like receptor agonists LPS or polyICLC in combination with incomplete Freund’s adjuvant in melanoma patients
... for peptide vaccines in melanoma has been an incomplete Freund’s adjuvant ...(IFA). Peptide vaccines incorporating IFA have induced circulating T cell responses [1–3], but some are weak and transient ...for ...
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Genetic Pathway of HIV-1 Resistance to Novel Fusion Inhibitors Targeting the Gp41 Pocket
... C peptide adopt a unique M-T hook structure, in which Thr116 redirects the peptide chain to position Met115 above the left side of the pocket so that its side chain caps the pocket to stabilize the ...
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Antimicrobial activity of an antimicrobial peptide against amastigote forms of Leishmania major
... secondary infection by bacteria or fungi is one of the main problems in leishmaniasis treatment. Given the antibacterial and antifungal effects of AMPs, the use of these peptides can also be effective in bacteria and ...
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Multilayer nanoscale encapsulation of biofunctional peptides to enhance bone tissue regeneration in vivo.
... Other 76 short peptide fragments proposed in literature for bone regeneration are the hexapeptide 77 fragment GFOGER, extracted from collagen type I, that stimulates the differentiation [r] ...
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Original Article The role of human prostate cancer specific binding peptide on the malignant phenotype of PC-3M cell
... novel short peptide (B08: human prostate cancer specific binding peptide) on the malignant phenotype of the human prostate cancer cell line ...7-mer peptide library to screen the target ...
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Cytokeratins mediate epithelial innate defense through their antimicrobial properties
... 19-mer peptide also showed bactericidal activity against the invasive clinical isolate 6294 in physiological saline, a ...natural peptide sequence (P < ...scrambled peptide control (100 μg/ml, 15 ...
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Recent development of amino acids and peptides in metal ions detection: An overview
... the peptide backbone and also on the amino acid side ...of peptide permits polydentate chelation which can provide strong binding and fast kinetic with ...the peptide and can be optimized by further ...
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IFN γ protects short term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A dependent mechanism
... against peptide-pulsed HLA-A11–positive OVAC 16. This revealed that peptide-specific lysis was also inhibited by IFN-γ treatment of this OVAC (P < ...a peptide- pulsed HLA-A11–transfected LCL line ...
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Variability and Immunogenicity of Caprine Arthritis-Encephalitis Virus Surface Glycoprotein
... amino acid substitutions relative to the consensus sequence and smoothed using a 10-amino-acid window size. The first conserved region (C1) spanning 86 amino acids corresponded to the amino terminus of SU. This region ...
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New linear antiplasmodial peptides related to angiotensin II
... during peptide-membrane interactions [23, ...simulate peptide-membrane interactions, simulating natural biological environments [25]; TFE induce an α-helix formation and stabilize the secondary structure ...
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Antibacterial Properties and Efficacy of a Novel SPLUNC1 Derived Antimicrobial Peptide, α4 Short, in a Murine Model of Respiratory Infection
... growth of all three MDR strains of P. aeruginosa at a concentration as low as 2 M (Fig. 4A, B, and C). In addition, using the standard crystal violet method, we demon- strated that ␣ 4-short retained the ability ...
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Characterisation of major peptides in "Jack Jumper" ant venom by mass spectrometry
... The possibility of genetic variation explaining the apparent difference from published data was considered. We analysed venom samples from several different sources within Tasmania and an earlier reference sample from ...
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Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists
... phage-displayed peptide library was screened for P- selectin binders ...their peptide insert (Table ...EWVDV peptide would greatly benefit from further optimiza- tion ...
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Circulating glucagon-like peptide-1 increases in response to short-term overfeeding in men
... very short half-life and is found in low concentra- tions, before it is degraded by DPP-IV, while total GLP-1 gives an indication of the secretion from intestinal ...
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