Sia, sialic acid
Neurotropism of Enterovirus D68 Isolates Is Independent of Sialic Acid and Is Not a Recently Acquired Phenotype
... for sialic acid for infection with EV-D68, cultures of various cells, including rhabdomyosarcoma (RD) cells, the cells used for propagation and titration of the virus, and N2A cells, were incubated with ...
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Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells
... later, the cells were incubated with control virions, digested virions, or virions incubated with either Maackia amurensis lectin (MAL1) or Elderberry bark lectin (ELD) (Table 1) at 4°C for 1 h. The MAL1 lectin has a ...
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Plasma sialic acid levels in the offspring of one parent with Type 2 diabetes mellitus
... Fasting blood was collected in bottles containing diso- dium ethylene diamine tetraacetate Dehydrate (EDTA) and the plasma was separated immediately by centrifuga- tion at 3000 rpm for 15 minutes at 4 0 C. Total ...
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A Study of Lipid- and Protein- Bound Sialic Acids for the Diagnosis of Bladder Cancer and Their Relationships with the Severity of Malignancy
... Results: Mean levels of both markers were found to be significantly higher in the patients than the healthy controls. Positive correlations were observed between serum levels of lipid- (r=0.283, p<0.05) and protein- ...
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Sialic Acid of Human Blood Platelets
... The release of sialic acid from platelets by influenza lyzed platelet remnants were spun down 21,000 X g for 2 hours, the supernatant fluid neutralized with 0.1 M virus, neuraminidase, a[r] ...
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Expression of 9 O and 7,9 O Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses
... 9-O-acetyl sialic acid production and trafficking in cells. (Step 1) Sia (purple diamond) is added to the growing glycan chain in the Golgi by sialyltransferases using CMP-Neu5Ac or CMP-Neu5Gc ...
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Studies on the defect underlying the lysosomal storage of sialic acid in Salla disease Lysosomal accumulation of sialic acid formed from N acetyl mannosamine or derived from low density lipoprotein in cultured mutant fibroblasts
... free sialic acid was 5-10 times higher in mutant than in normal ...extracellular sialic acid, low-density lipoprotein (LDL) was labeled in the sialic acid moiety ...
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Serum and Urine Sialic Acid in Sickle Cell Nephropathy
... [8]. Sialic acid-rich glycoprotein is found mainly in cell membranes and elevated levels may indicate excessive cell membrane damage, but more specifically for cells of vascular ...addition, sialic ...
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SIALIC ACID TRANSPORT IN E. COLI: ROLE OF OUTER MEMBRANE PORIN NANC
... Sialic acid is a nutrient of bacteria important in host-pathogen ...of sialic acid from outer membrane to periplasmic space of Escherichia coli is not ...N-acetylneuraminic acid ...
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Sialic acid metabolism as a potential therapeutic target of atherosclerosis
... total sialic acid (TSA) levels contributed to increased risk of future cardiovascular events independent of BMI, cholesterol and socioeconomic position ...[6]. Sia also associated with a number of ...
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Bacterial sialic acid degradation: membrane transport and enzymology
... NanT sialic acid transporter, no crystals were obtained in lipidic cubic phase, but unusual crystals were obtained in the MemGold™ vapour diffusion ...NanT sialic acid transporter is also ...
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SIALIC ACID IN HUMAN SEMEN AND IN THE MALE GENITAL TRACT
... As part of a study on the role of sialic acid in fertilization, we have assayed a series of normal and subnormal human semen specimens as well as human prostatic and seminal vesicle secr[r] ...
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BOVINE TRANSFERRINS: SIALIC ACID AND THE COMPLEX PHENOTYPE
... Although the protein in this band has not been isolated and studied, it seems unlikely to be related to sialic acid differences, since in human transferrin all the mole[r] ...
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Sizing up sialic acid in glomerular disease
... in sialic acid biosynthe- sis (see the related article beginning on page ...of sialic acid, suffer from hematuria, proteinuria, and structural defects in the glomerulus and die within days ...
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Differential Infection of Polarized Epithelial Cell Lines by Sialic Acid-Dependent and Sialic Acid-Independent Rotavirus Strains
... Infection of epithelial cells by some animal rotaviruses, but not human or most animal rotaviruses, requires the presence of N-acetylneuraminic (sialic) acid (SA) on the cell surface for efficient ...
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Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses
... We investigated the interactions of rotaviruses with glycoproteins and cells that support rotaviral replication. We found that a wide range of naturally occurring glycoproteins, including ovalbumins and ovomucoids from ...
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1. Study on sialic acid as biomarker of cancer
... on sialic acid as a tumor marker should be examined from the perspective of aberrant glycosylation in cancer cell membranes owing to activation of new glycosyl transferases that are characteristic of tumor ...
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Specificity and Affinity of Sialic Acid Binding by the Rhesus Rotavirus VP8* Core
... mM sialic acid in an ␣2,6 linkage to lactose (6⬘ sialyllactose) match those in the presence of the same quanti- ties of sialic acid in an ␣2,3 linkage to lactose (3⬘ sialyllactose) ...Free ...
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Sialic acid transporter NanT participates in Tannerella forsythia biofilm formation and survival on epithelial cells
... use sialic acid either as a nutrient, or to decorate their surface molecules such as lipopolysaccharides (LPS), lipooligosacharide (LOS), or capsule to escape from the host immune defense system [9], [10], ...
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Sialic Acid Functions in Enterovirus 70 Binding and Infection
... that sialic acid residues in the complex-type N-linked oligosaccharide may contribute to EV70 binding to ...the sialic acid residues critical for EV70 binding are not a component of the ...
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