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sickle cell disease

Predictors and Correlates of Fatigue in Sickle Cell Disease Patients

Predictors and Correlates of Fatigue in Sickle Cell Disease Patients

... This study provides new information about the frequency, severity, and resulting interference of fatigue in patients with SCD. Our results showed that more than 40% of adults with sickle cell ...

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Intravascular hemolysis and the pathophysiology of sickle cell disease

Intravascular hemolysis and the pathophysiology of sickle cell disease

... kidney disease, and large-artery ischemic ...by cell-free hemoglobin in a dioxygenation reaction that also oxidizes hemoglobin to methemoglobin, a non–oxygen-binding form of hemoglobin that readily loses ...

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“HÉMODYA”: A PHYTOMEDECINE FOR SICKLE CELL DISEASE MANAGEMENT IN CAMEROON

“HÉMODYA”: A PHYTOMEDECINE FOR SICKLE CELL DISEASE MANAGEMENT IN CAMEROON

... different disease treatments, the phytochemist on the chemical constituents and the pharmacologist on the effectiveness of particular plant compound or ...of Sickle cell ...

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Keeping warm with sickle cell disease research project

Keeping warm with sickle cell disease research project

... of Sickle Cell Sufferers of Yorkshire and Africa and Basic Information); Oscar Birmingham; Oscar Sandwell; Oscar Nottingham; The Sickle Cell Society; advice from health professionals in ...

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The Effect of Hydroxyurea on Vasculopathy in a Child with Sickle Cell Disease

The Effect of Hydroxyurea on Vasculopathy in a Child with Sickle Cell Disease

... Summary: We report serial CNS findings in a girl with sickle cell disease and stroke. Religious considerations pre- cluded transfusion and bone marrow transplantation; therefore, she received ...

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The spectrum of brain MR abnormalities in sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease

The spectrum of brain MR abnormalities in sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease

... Infarction or ischemia in border-zone areas could result from either vasoocclusion within the cerebral vessels or transient reduction in perfusion pressure. The latter might accom- pany a hypoxic or hypovolemic episode ...

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Evaluation of SWI in Children with Sickle Cell Disease

Evaluation of SWI in Children with Sickle Cell Disease

... with sickle cell disease and age- and sex-matched healthy control participants was ...with sickle cell disease vs the control group (P ⬍ ...with sickle cell ...

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Intravital microscopy of capillary hemodynamics in sickle cell disease

Intravital microscopy of capillary hemodynamics in sickle cell disease

... homozygous sickle cell disease (HbSS red ...red cell (rbc) flux exhibited greater intermittence compared with normal subjects, which increased with painful ...red cell sequestration ...

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Study of pulmonary hypertension as a complication of sickle cell disease

Study of pulmonary hypertension as a complication of sickle cell disease

... Background: Sickle cell anaemia is the most common inherited hematological abnormality across human race, particularly prevalent in pockets of central India and pulmonary hypertension (PH) supposedly ...

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SICKLE CELL DISEASE- AN AYURVEDIC PERSPECTIVE .......

SICKLE CELL DISEASE- AN AYURVEDIC PERSPECTIVE .......

... Sickle cell disease or Sickle cell anemia is a genetic disease seen amongst various tribal populations of India that affects the ...hemoglobin. Sickle cell anemia ...

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THE EFFECT OF METHEMOGLOBIN FORMATION IN SICKLE CELL DISEASE

THE EFFECT OF METHEMOGLOBIN FORMATION IN SICKLE CELL DISEASE

... When sodium nitrite was administered to patients with sickle cell disease and the methemoglobin concentration of the blood reached levels greater than 20 per cent of the total pigment, t[r] ...

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Hepcidin and Erythropoietin Level in Sickle Cell Disease

Hepcidin and Erythropoietin Level in Sickle Cell Disease

... kidney disease. As sickle cell disease is characterized by chronic immune activation, and malignancy, these conditions could lead to increased level of interluetkin-6 which stimulates ...

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Depression and loneliness in Jamaicans with sickle cell disease

Depression and loneliness in Jamaicans with sickle cell disease

... The demographic data collected included age, sex, mari- tal status, genotype, employment status, and the highest educational level they had attained. Questions were also included on their utilization of the clinic (SCU) ...

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Mycoplasma Disease and Acute Chest Syndrome in Sickle Cell Disease

Mycoplasma Disease and Acute Chest Syndrome in Sickle Cell Disease

... ABSTRACT. Background. Acute chest syndrome (ACS) is the leading cause of hospitalization, morbidity, and mortality in patients with sickle cell disease. Radio- graphic and clinical findings in ACS ...

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SALMONELLA OSTEOMYELITIS COMPLICATING SICKLE CELL DISEASE

SALMONELLA OSTEOMYELITIS COMPLICATING SICKLE CELL DISEASE

... (H.J., Case 1.) Salmonella osteomyeLtis involving humerus, radius and ulna, producing extensive destruction, cortical fissuring and sclerosis in a patient with sickle cell disease.. FIG.[r] ...

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Transition and Sickle Cell Disease

Transition and Sickle Cell Disease

... Sickle cell disease (SCD), the most common genetic disease screened for in the newborn period, occurs in ∼ 1 in 2400 newborns in the general population and 1 in 400 individuals of African ...

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Sickle Cell Disease: A Question of Equity and Quality

Sickle Cell Disease: A Question of Equity and Quality

... concerning sickle cell disease treatment was passed, resulting in the development of comprehensive sickle cell ...the Sickle Cell Treatment Act, designed to substantially ...

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Renal manifestations of sickle cell disease in children

Renal manifestations of sickle cell disease in children

... Sickle cell anaemia (SCA; homozygous sickle haemoglobin [HbS], ...In sickle cell anemia, HbSS is commonly as high as 90%of total haemoglobin; whereas in sickle cell ...

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Health Supervision for Children with Sickle Cell Disease

Health Supervision for Children with Sickle Cell Disease

... ABSTRACT. Sickle cell disease (SCD) is a group of complex genetic disorders with multisystem manifesta- ...other disease-specific health maintenance services, psychoso- cial care, and genetic ...

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Prostacyclin and Platelet Aggregation in Sickle Cell Disease

Prostacyclin and Platelet Aggregation in Sickle Cell Disease

... Patients with sickle cell disease have certain platelet function abnormalities that may relate to vaso-occlusive episodes.’4 Various abnormalities of platelet function include increased [r] ...

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