signalling pathway
Exosomes derived from Wharton's jelly of human umbilical cord mesenchymal stem cells reduce osteocyte apoptosis in glucocorticoid-induced osteonecrosis of the femoral head in rats via the miR-21-PTEN-AKT signalling pathway
... Figure 4. (A) Main reported miRNAs participating in apoptosis, bone-related diseases, and miRNAs present in exosomes; some miRNAs are multifunctional and are members of several groups, e.g. miR-21, miR-155, and miR-125b. ...
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Dauer signalling pathway model for Haemonchus contortus
... dauer signalling pathway in ...of signalling molecules between the infec- tive L3 stage of ...from signalling to other biological processes, such as immunomodulation, in parasitic nematodes ...
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Computational Models of the NF- B Signalling Pathway
... Like the minimal model of Krishna et al. [86] above, Longo et al. [89] also used the Hoffmann model as the basis for developing a minimal model of negative feedback within the NF-κB signalling pathway. This ...
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Prevention of Encephalomyocarditis Virus-Induced Diabetes in Mice by Inhibition of the Tyrosine Kinase Signalling Pathway and Subsequent Suppression of Nitric Oxide Production in Macrophages
... kinase signalling pathway might be involved in the activation of macrophages by EMC-D virus infection and whether tyrosine kinase inhibitors might, therefore, abrogate EMC-D virus-induced diabetes in ...
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Adaptation at the output of the chemotaxis signalling pathway
... chemotaxis signalling pathway allows bacterial cells to sense and respond to changes in concentrations of chemical attractants or repellents 1–2 ...chemotaxis pathway is well known for its high gain ...
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WNT signalling pathway in oral lesions
... WNT/-catenin signalling plays a fundamental role in bone biology, and aberrations in WNT pathway play a critical role in bone destruction related to periapical and periodontal ...WNT signalling in ...
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The role of the Eph signalling pathway in epithelialisation of the somites
... Notch signalling is not the arrest o f the dynamic expression o f her-1 and Delta C but the loss o f synchronisation between expressing cells (Jiang et ...Notch signalling during somitogenesis is not as ...
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The Lophotrochozoan TGF β signalling cassette diversification and conservation in a key signalling pathway
... TGF-b/BMP signalling cascades and Lophotrochozoan ...TGF-b/BMP signalling cascades: representation of the canonical signalling pathways for TGF-b-like and BMP-like cascades with inhibitors of ...
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Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy
... ERK signalling cascade may contribute to the aetiology underlying some other epileptic types in humans (Nateri et ...cytoprotective signalling cascades including AKT and ...AKT-mTOR signalling ...
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Original Article Ketamine impairs learning and memory ability in early developing mice via the hippocampal PKA/CREB signalling pathway
... mice [3, 4]. Clinical and experimental studies have reported that ketamine can also cause schizophrenia-like symptoms and cognitive impairment in people [5]; however, the molecu- lar biological mechanism of ...
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Necessity to evaluate PI3K/Akt signalling pathway in proarrhythmia
... the pathway might be very crucial in addressing proar- ...PI3K/Akt signalling pathway in cardiac protection is ...the pathway in ...the pathway in proarrhythmia using in vivo genetic ...
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Regulation of the BMP signalling pathway by BMP1-related metalloproteases
... nt signalling pathw ay, has no effect on dorsal mesoderm formation in the early X enopus em bryo (H oppler et ...Wnt signalling pathway responsible for inactivating p-catenin, induces a secondary ...
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Reconstruction of the insulin like signalling pathway of Haemonchus contortus
... survival within the host, and regulates parasite transmission and population size [88], understanding this phenomenon is of critical importance. Hence, future work should evalu- ate the involvement of IIS and associated ...
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Regulation of neuritogenesis in neuroblastoma cells by components of the Wnt signalling pathway
... The reason for the discrepancies in the results of these groups is not clear. Perhaps the differences are simply due to different experimental procedures or the use of different systems, or perhaps both the GSK-3 and ...
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Original Article Osthole attenuates adjuvant-induced arthritis in rats by suppressing inflammation and oxidative stress via the SIRT1/TLR4/NF-κB pathway
... Abstract: Osthole (Ost) is a natural coumarin, mainly isolated from Cnidium monnieri. It has effects in many dis- eases, including tumours, osteoporosis, and inflammation. However, its molecular mechanism in arthritis ...
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CATECHIN: A TLR4 MEDIATED CHAIN BREAKING INHIBITOR OF SIGNALLING CASCADE IN ENDOTOXIN-INDUCED LIVER INJURY
... of signalling molecules involved in endotoxin mediated signalling pathway, levels of hepatic oxidative markers and antioxidants were analyzed in both endotoxin (10 mg/kg body weight injected ...
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Temporal progression of hypothalamic patterning by a dual action of BMP
... BMP/Wnt signalling pathway is sufficient to induce Gli3 in the hypothalamus: first, overexpression of pSmad5 does not lead to Gli3 upregulation; second, inhibition of pSmad signalling by dorsomorphin ...
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Interleukin 6 and rheumatic diseases
... IL-6 signalling pathway in patients with inflammatory diseases characterized by IL-6 overproduction may be of benefit to patients that have a very high risk for coronary artery ...
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MDA19, a novel CB2 agonist, inhibits hepatocellular carcinoma partly through inactivation of AKT signaling pathway
... AKT signalling pathway, could be reversed by CB2 ...AKT signalling pathway in HCC, therefore MDA-19 treatment may be a promising strat- egy for HCC ...
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An In Silico Comparative and Pathway Analysis of Targeted Genes of Diabetic Retinopathy: A Prognostic Approach towards Diabetic Retinopathy
... target pathway interactions were performed for miRNA 21 and their targeted gene IL1B by using mirwalk database, their interaction was found in apoptosis and MAPK signalling pathway which are ...
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