skeletal muscle regeneration
microRNA 206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
... Delayed skeletal muscle regeneration in mice lacking ...during skeletal muscle regeneration and its enrichment in activated SCs (25), we injected WT and miR-206–KO mice with CTX ...
13
A role for Galgt1 in skeletal muscle regeneration
... in muscle regeneration, satellite cell activation and differentiation, myoblast migration and fusion, and myofiber growth are mediated by signaling molecules including Akt and Wnt kinases, mTOR, Notch ...
16
Pax7 expressing satellite cells are indispensable for adult skeletal muscle regeneration
... and regeneration (Lepper et ...in skeletal muscle regeneration in the ...regulate muscle homeostasis (Joe et ...resident muscle stem cells with the capacity to generate ...
11
Poly(ε-caprolactone) Resorbable Knitted Auxetic Scaffolds for Craniofacial Skeletal Muscle Regeneration.
... Craniofacial microsomia is a congenital deformity caused by asymmetric development of the skull (cranium) and face before birth. Current treatments include corrective surgery and replacement of the deformed structure ...
76
Nontranslational function of leucyl tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration
... While it can be assumed that the translational function of LRS is necessary for myogenesis, a process involving robust pro- tein synthesis, whether LRS has any noncanonical function in myogenesis is unknown. Here we ...
7
HEXIM1 controls satellite cell expansion after injury to regulate skeletal muscle regeneration
... that skeletal muscle regeneration, which is achieved by the de novo formation of myofibers from the satellite cell pool, is controlled by the HEXIM1/P-TEFb pathway that regulates satellite cell ...
16
Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage
... Skeletal muscle regeneration was first properly described in the 1860s, but almost a century elapsed before the cellular mechanisms of this process were resolved (Scharner and Zammit, ...regenerating ...
12
An absolute requirement for Pax7 positive satellite cells in acute injury induced skeletal muscle regeneration
... for muscle repair during injury-induced ...dystrophic muscle of a single muscle fiber along with its satellite cells generates plentiful new myofibers and myofiber-associated cells (Collins et ...
8
Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration
... The present study shows that CXCL12 is crucial for proper muscle regeneration. We highlight that this homing molecule could play an important role in drastic muscle injuries and that the ...
15
Distinct patterns of MMP 9 and MMP 2 activity in slow and fast twitch skeletal muscle regeneration in vivo
... differential regeneration ability of fast (EDL) and slow twitch (Soleus) muscles might result from differential MMPs action in ECM ...diseased muscle fibers, in mononuclear cells and along the sarcolemma ...
9
PPARδ regulates satellite cell proliferation and skeletal muscle regeneration
... in skeletal muscle progenitors (satellite cells) is ...weight, muscle size or muscle composition, they later developed metabolic syndrome, which manifested as increased body weight and reduced ...
16
Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling
... promotes skeletal muscle growth mainly by modulating protein synthesis and degradation ...enhances skeletal muscle regeneration [43], an ordered progression from the activation of ...
10
The miR-206/133b cluster is dispensable for development, survival and regeneration of skeletal muscle
... such muscle might be affected by inactivation of miR- 206/133b in conditions of constant ...of muscle cre- atine kinase (MCK) from muscle fibers into the blood, which serves as an indicator of ...
13
Purinergic signalling in mammalian skeletal muscle development and regeneration
... mouse, muscle degeneration and regeneration does not result in such marked progressive muscle weakness and premature death as occurs in ...mdx skeletal muscle, which is capable of ...
328
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
... facilitated skeletal muscle regeneration through enhanced satellite cell activation and reduced ...of muscle homeostasis and suggest a combined role for IKK inhibitors and growth factors in ...
11
The origins and non canonical functions of macrophages in development and regeneration
... tissue regeneration is ...are muscle diseases associated with a continuous succession of degeneration/regeneration cycles, eventually leading to disruption of the regenerative process and alterations ...
14
The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration
... We thank all the lab members and alumni for the technical and scientific support, especially Ms Lin Yi, Mr Chihkai Chang, Ms Vittoria Canale, Ms Claudia Hopkins, Dr Bernhard Lehnertz, Dr Dario Lemos, Dr Pretheeban ...
10
Transplanted hematopoietic stem cells demonstrate impaired sarcoglycan expression after engraftment into cardiac and skeletal muscle
... to skeletal and cardiac muscle regeneration after ...and skeletal muscle using a model of cardiomyopathy and muscular dystrophy that lacks ...and skeletal muscle that ...
10
Myoprotective effects of bFGF on skeletal muscle injury in pressure-related deep tissue injury in rats
... of muscle-specific structural proteins ...injured muscle regeneration [29, ...hanced skeletal muscle regeneration in response to fiber injury ...physiological muscle ...
10
Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle
... anterior muscle cross sectional area dem- onstrated differences at p56 between ΔKlotho and con- trol littermates (Additional file 1: Figure ...in muscle growth or due to a premature aging phenotype which ...
14