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Spatial Learning and Memory

Impairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms

Impairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms

... in learning efficiency and spatial memory in the MPA-modified CdTe QD-treated rats by using open-field and Y-maze tests, which could be attributed to pathological changes and disruption of ...

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The Role of Aromatase and Castration on Spatial Learning and Memory Changes by Nandrolone

The Role of Aromatase and Castration on Spatial Learning and Memory Changes by Nandrolone

... impairs learning and memory in adults [1, 4]; however, the underlying mechanism is ...the spatial learning and memory of animals and hu- mans are ...impair spatial ...

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Cdk5/p35 functions as a crucial regulator of spatial learning and memory

Cdk5/p35 functions as a crucial regulator of spatial learning and memory

... We have previously demonstrated an impairment of spatial learning and memory, and hippocampal LTD in- duction in p35 knockout (KO) mice. However, p35KO mice exhibit reversed cortical lamination of ...

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Original Article Memantine improves spatial learning and memory of pentylenetetrazole-kindled rats with increasing Arc/Arg3.1 and CaMKIIα expression

Original Article Memantine improves spatial learning and memory of pentylenetetrazole-kindled rats with increasing Arc/Arg3.1 and CaMKIIα expression

... of learning and mem- ory of rats in epileptic group and also revers- ed the expression of GluR1, ...the spatial learning and memory might be associated with the ...

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Chronic Administration of Donepezil on Inhibitory and Spatial Learning and Memory in Male Rats

Chronic Administration of Donepezil on Inhibitory and Spatial Learning and Memory in Male Rats

... total memory and working memory errors of donepezil-treated rats was significantly less than that of the saline-treated ...the learning process, but it can improve memory performance in normal ...

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Anti-depressant effects of Baluchi's formulation on spatial learning and memory

Anti-depressant effects of Baluchi's formulation on spatial learning and memory

... and/or herbal medicine including powerful antioxidant may somewhat preserve the brain from damages caused by oxidants related to Alzheimer, leading to fewer neuronal deaths [5]. In this study, Baluchi's formulation is ...

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Spatial learning and memory in the tortoise (Geochelone carbonaria)

Spatial learning and memory in the tortoise (Geochelone carbonaria)

... about spatial locations, to remember which have been visited, and to adopt a strategy of going to those that have not been visited previously (or of avoiding those that ...identifies spatial locations by ...

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Nano-zinc oxide damages spatial cognition capability via over-enhanced long-term potentiation in hippocamus of Wistar rats

Nano-zinc oxide damages spatial cognition capability via over-enhanced long-term potentiation in hippocamus of Wistar rats

... on spatial learning and memory and synaptic plasticity in the hippocampus of young rats, and tried to interpret the underlying ...The spatial learning and memory ability was ...

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Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2

Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2

... Fig. 5 Identification of TPM2 as a downstream target of Smad4 SUMOylation. Knockdown of TPM2 impairs spatial learning and memory formation. a Animals received Flag-vector, Flag-Smad4WT, or ...

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Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1 ΔE9 mice: potential mechanism underlying cognitive impairment

Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1 ΔE9 mice: potential mechanism underlying cognitive impairment

... recognition memory, spatial learning and memory, active and passive avoidance were deteriorated and neuroendocrine immunomodulation (NIM) network was imbalance in SAMP8 and APP/ PS1 ...

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BAI1 regulates spatial learning and synaptic plasticity in the hippocampus

BAI1 regulates spatial learning and synaptic plasticity in the hippocampus

... hippocampus-dependent spatial learning and memory that are accompanied by enhanced long-term potentiation (LTP), impaired long-term depression (LTD), and a thinning of the postsynaptic density (PSD) ...

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LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice

LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice

... recognition memory, spatial learning and memory, a passive or active avoidance response, neuron loss, and Aβ deposits, and could be regulated by LW-AFC ...for learning and memory ...

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Alloparenting enhances the emotional, social and cognitive performance of female African striped mice, Rhabdomys pumilio

Alloparenting enhances the emotional, social and cognitive performance of female African striped mice, Rhabdomys pumilio

... conspecifics for resources) and spatial learning and memory (locating food in the environment) of female alloparental striped mice. We also investigated whether direct exposure to young is required ...

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The Deterioration of Spatial Memory and the Role of the Masticatory Function during Aging: A Brief Literature Review

The Deterioration of Spatial Memory and the Role of the Masticatory Function during Aging: A Brief Literature Review

... in spatial memory when evaluated using the Morris Water Maze ...in spatial learning and memory in 18-month-old ...impairs spatial learning and memory when evaluated ...

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Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states

Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states

... Thus, we investigated the effects of "neonatal handling" on factors influencing cognitive abilities and affective states of the adult rat. Specifically, we determined the "neonatal handling" effects on A. ...

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Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects

Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects

... assess spatial learning and memory, we then per- formed a Morris water maze ...in spatial learning ...diminished spatial memory acquisition and memory ...cued ...

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Neuroprotective effect of panax notoginseng saponins and its main components

Neuroprotective effect of panax notoginseng saponins and its main components

... the learning ability and memory fun- ction of rats [34], improve the spatial learning ability, re- duce the size of infarction area, promote Functional re- covery of brain tissue ...improve ...

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Time Course of Changes in Passive Avoidance and Y-maze Performance in Male Diabetic Rats

Time Course of Changes in Passive Avoidance and Y-maze Performance in Male Diabetic Rats

... of learning and memory is also recognized as a complication of diabetes ...rat, spatial learning impairments have also been ...and memory, these areas are very vulnerable to oxidative ...

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Evaluation of Rosmarinus officinalis L. extract on spatial memory, learning and antioxidant enzymes activities in the hippocampus of rats

Evaluation of Rosmarinus officinalis L. extract on spatial memory, learning and antioxidant enzymes activities in the hippocampus of rats

... and the sub-granular layer (in dentate gyrus of hippocampus). Thus, the adult brain tissue has more ability for plasticity at the cellular level than it was thought in the past. It is believed that newly formed neurons ...

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The effect of rosemary extract on spatial memory, learning and antioxidant enzymes activities in the hippocampus of middle-aged rats

The effect of rosemary extract on spatial memory, learning and antioxidant enzymes activities in the hippocampus of middle-aged rats

... the memory and antioxidant status of the hippocampus in middle-aged ...on learning and spatial memory in rats by Morris Water Maze test, pyramidal cells survival of CA1 area in hippocampus, ...

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