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Spermatogonial stem cells

Spermatogonial Stem Cells: A Review of Essential Factor for Self-Renewal and Differentiation

Spermatogonial Stem Cells: A Review of Essential Factor for Self-Renewal and Differentiation

... Fig. 1: A schematic representation of signaling model towards self-renewal and differentiation of SSC. BCL6b: B cell CLL/lymphoma 6; bFGF: Basic fibroblast growth factor; EGF: Epidermal growth factor; ETV5: Ets variant ...

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Establishment of Oxidative Stress Modeling during Spermatogonial Stem Cells Cultivation Treated with Different Doses of H2O2

Establishment of Oxidative Stress Modeling during Spermatogonial Stem Cells Cultivation Treated with Different Doses of H2O2

... germ cells that leads to produc- tion of an unlimited number of spermatozoa [14, ...through spermatogonial stem cells which are located on basement membrane of seminifer- ous ...

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The role of fibroblast growth factor receptor 2 (FGFR2) in differentiation of bovine spermatogonial stem cells (SSCs)

The role of fibroblast growth factor receptor 2 (FGFR2) in differentiation of bovine spermatogonial stem cells (SSCs)

... testicular cells in collagen gel ...bovine spermatogonial stem cells and gene expression of niche factors regulating their development in ...

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Xenotransplantation of canine spermatogonial stem cells (cSSCs) regulated by FSH promotes spermatogenesis in infertile mice

Xenotransplantation of canine spermatogonial stem cells (cSSCs) regulated by FSH promotes spermatogenesis in infertile mice

... Spermatogonial stem cells (SSCs) are responsible for pro- moting the maintenance of spermatogenesis [1, 2]. There- fore, SSCs could be widely used in a number of recently developed and important ...

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Assessment of Nycodenz Gradient on Enrichment and Culture of Perinatal Porcine Spermatogonial Stem Cells

Assessment of Nycodenz Gradient on Enrichment and Culture of Perinatal Porcine Spermatogonial Stem Cells

... of spermatogonial stem cells into testes was expanded to larger animal species recipients including the monkey, bovine, rat, and human (Schlatt et ...the spermatogonial stem ...

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Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse

Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse

... The decline of quantity and quality of sperm are correlated with the increasing age and some anti-cancer compounds such as busulfan. Previous studies have shown that Resveratrol (Res) inhibits tumorigenesis and ...

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Differentiation of zebrafish spermatogonial stem cells to functional sperm in culture

Differentiation of zebrafish spermatogonial stem cells to functional sperm in culture

... self-renewing spermatogonial stem cells (SSCs) in cell culture conditions, using zebrafish testicular hyperplasia cells that accumulate early stage ...feeder cells, they differentiated ...

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Enhancement in colonization of bovine spermatogonial stem cells following addition of knock-out serum replacement to culture medium

Enhancement in colonization of bovine spermatogonial stem cells following addition of knock-out serum replacement to culture medium

... germ cells prior to injection into recipient seminiferous tubules is of importance in spermatogonial stem cells (SSCs) ...as cells having been cultured with FBS (10%) for three days ...

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The interaction between Sertoli cells and luekemia inhibitory factor on the propagation and differentiation of spermatogonial stem cells in vitro

The interaction between Sertoli cells and luekemia inhibitory factor on the propagation and differentiation of spermatogonial stem cells in vitro

... other stem cells (14, ...Thy-1+ cells had high purity and expressed two specific surface markers for spermatogonial stem cells ...spermatid-like cells in ...Sertoli ...

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PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells

PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells

... SSCs: Spermatogonial stem cells; PAMAM: Poly(amidoamine); G5: The fifth generation of PAMAM dendrimers; cRGD: Cyclic arginine-glycine-aspartic acid; G5-cRGD: PAMAM-cRGD dendrimers; FTIR: Fourier ...

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Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes

... Spermatogonial stem cells (SSCs) are a subpopulation of type A spermatogonia [15, ...unipotent stem cells, differentiating into sperm ...ES-like cells that are capable of giving ...

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PTEN signaling is required for the maintenance of spermatogonial stem cells in mouse, by regulating the expressions of PLZF and UTF1

PTEN signaling is required for the maintenance of spermatogonial stem cells in mouse, by regulating the expressions of PLZF and UTF1

... Background: Pten plays a crucial role in the stem cell maintenance in a few organs. Pten defect also causes the premature oocytes and ovary aging. We and other groups have found that the phosphatidylinositol-3-OH ...

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Characterization and Transplantation of Felid Spermatogonial Stem Cells

Characterization and Transplantation of Felid Spermatogonial Stem Cells

... Spermatogonial stem cells (SSCs) and undifferentiated spermatogonia are the only stages of the male gamete capable of replicating, therefore, in vitro expansion of these valuable cells would ...

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Separating mouse malignant cell line (EL4) from neonate spermatogonial stem cells utilizing microfluidic device in vitro

Separating mouse malignant cell line (EL4) from neonate spermatogonial stem cells utilizing microfluidic device in vitro

... tumor cells and spermatogonial stem cells after microfluidic isolation were collected at two outlets, and the outputs for smaller tumor cells were approximately ...larger cells ...

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NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells

... Results: In our studies, Overexpression of the Notch1 NICD promoted development of the reproductive ridge, but inhibited the formation of seminiferous tubules. The formation efficiency of PGCs in the reproductive ridge ...

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Akt mediates self renewal division of mouse spermatogonial stem cells

Akt mediates self renewal division of mouse spermatogonial stem cells

... Spermatogonial stem cells have unique properties to self-renew and support spermatogenesis throughout their ...for spermatogonial stem cells, the molecular mechanism of ...

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Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis

Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis

... Spermatogonial stem cells (SSCs) capable of self-renewal and differentiation are the foundation for sper- ...with stem cell ...the stem cell state and revealed what we believe to be ...

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Evaluation of the effect of follicular stimulating hormone on the in vitro bovine spermatogonial stem cells self-renewal: An experimental study

Evaluation of the effect of follicular stimulating hormone on the in vitro bovine spermatogonial stem cells self-renewal: An experimental study

... from spermatogonial stem cells (SSCs) and produce mature spermatozoa ...Sertoli cells, basal membrane and, interstitial cells are the main components of SSCs niche ...Sertoli ...

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Effects of nano-selenium on mRNA expression of markers for spermatogonial stem cells in the testis of broiler breeder males

Effects of nano-selenium on mRNA expression of markers for spermatogonial stem cells in the testis of broiler breeder males

... Fertility is one of the most important parameters in breeder farms and cockerels play an outstanding role in the fertility of eggs in broiler breeder farms. Todays, supplementation of chicken diet with additives such as ...

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MicroRNA-322 Regulates Self-renewal of Mouse Spermatogonial Stem Cells through Rassf8

MicroRNA-322 Regulates Self-renewal of Mouse Spermatogonial Stem Cells through Rassf8

... Spermatogonial stem cells (SSCs) are essential for spermatogenesis and male fertility. MicroRNAs (miRs) are key regulators of gene expression involved in self-renewal, differentiation, and apoptosis. ...

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