stavudine/d4T
A Phase I/II Evaluation of Stavudine (d4T) in Children With Human Immunodeficiency Virus Infection
... A Phase I/Il Evaluation of Stavudine (d4T) in Children With Human Immunodeficiency Virus Infection.. Mark W.[r] ...
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Combination Therapy With Stavudine (d4T) Plus Didanosine (ddI) in Children With Human Immunodeficiency Virus Infection
... with stavudine (d4T) plus didanosine (ddI) in symptomatic human immunodeficiency virus (HIV)-infected ...received d4T monotherapy in PACTG 240 were assigned to treat- ment with d4T plus ddI ...
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Sustained heavy ethanol drinking affects CD4+ cell counts in HIV infected patients on stavudine (d4T), lamivudine (3TC) and nevirapine (NVP) treatment regimen during 9 months follow up period
... on d4T/3TC/NVP regimen on CD4 + cell counts in Uganda using WHO AUDIT tool and chronic alcohol-use ...on stavudine (d4T) 30 mg, lamivudine (3TC) 150 mg and nevirapine (NVP) 200 mg and chronic alcohol ...
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Chronic Alcohol Consumption Affects Serum Enzymes Levels in the HIV Infected Patients on Stavudine (d4T)/Lamivudine (3TC)/Nevirapine (NVP) Treatment Regimen
... like stavudine (d4T) such as acute pancreatitis and hepatitis [46-50]; lamivudine (3TC) such as hepatomegally and lactic acidosis [46-50] and nevirapine such as hepatitis and hepatic failure ...
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beta estradiol attenuates the anti HIV 1 efficacy of Stavudine (D4T) in primary PBL
... The following reagents were obtained through the AIDS Research and Ref- erence Reagent Program, Division of AIDS, NIAID, NIH: AZT Resistant HIV-1 (Cat.# 629), provided by Dr. Douglas Richman, HIV-1 BAL, HIV-1 IIIB and ...
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A Randomized Comparative Trial of Stavudine (d4T) Versus Zidovudine (ZDV, AZT) in Children With Human Immunodeficiency Virus Infection
... This is a reflection of the higher rate of neutropenia ( , 400/ m L) observed among children receiving ZDV (1-year rate of 20% up to the time of the unblinding and 20% throughout the ent[r] ...
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Complete Phase-Out Stavudine Based Regimens in the Treatment of HIV-Infection: is it True That Stavudine Hasn’t Any Benefit Today? A Review
... to stavudine (d4T) combinations on virological and immunological recovery indicated that at week 80, 15/85 patients in the AZT arm and 14/85 patients in the d4T arm had reached the primary endpoint, ...
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FORMULATION, DEVELOPMENT AND EVALUATION OF MUCOADHESIVE MICROSPHERE OF STAVUDINE
... The stavudine has a very short half- life ...of stavudine are dose dependent and a reduction of the total administered dose reduces the severity of the ...toxicity. Stavudine is typically ...
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Prevalence of HIV 1 drug resistance amongst newly diagnosed HIV infected infants age 4–8 weeks, enrolled in three nationally representative PMTCT effectiveness surveys, South Africa: 2010, 2011–12 and 2012–13
... using stavudine (d4T) with lamivudine (3TC) and efavirenz (EFV) or nevirapine (NVP) if CD4 cell count was < 200 cells/mm 3 , or maternal zidovudine (AZT) prophylaxis from 28 weeks gestation with single ...
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Formulation and in-vitro evaluation of stavudine extended release tablets
... [3] Stavudine (D4T, thymidine) is the Food and Drug Administration approved drug for clinical use for the treatment of HIV infection, acquired immune deficiency syndrome (AIDS) and AIDS related conditions, ...
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A Time to Event Analysis of Adverse Drug Reactions Due to Tenofovir, Zidovudine and Stavudine in a Cohort of Patients Receiving Antiretroviral Treatment at an Outpatient Clinic in Zimbabwe
... of stavudine (D4T), zidovudine (AZT) or tenofovir (TDF) as part of NRTI ...TDF, d4T (30 mg), and AZT-based regimens maybe because data on TDF is limited particularly in sub-Saharan Af- rica where the ...
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Changes in Serum Liver Enzymes Level after Switching from Stavudine/Lamivudine to Zidovudine/Lamivudine in NNRTIs Based Anti-Retroviral Regimens in Hawassa, Southern Ethiopia
... included d4T backbone with one of NNRTI (either EFV or NVP) during HAART ...from d4T to AZT based regimen; whereas control were patients using AZT based regimen with either of EFV or NVP during HAART ...
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Microspheres Embedded In Microbeads: A Novel Approach to Improve Various Controlled Release Characteristics of Highly Water Soluble Drug through Ionic Gelation Method
... embedding stavudine loaded Eudragit RSPO microspheres into gellan microbeads by ionotropic gelation method with an aim to improve its controlled drug delivery ...containing D4T only are spherical in nature ...
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Changes in immunological, biochemical and hematological parameters of HIV-1 positive patients on antiretroviral therapy in Mbagathi County Hospital, Nairobi
... NRTIs (stavudine, zidovudine, lamuvudine, zabstbine thymidine and abacavir) are also commonly used in Kenya ( Max et al., 2012). Currently, a combination therapy with HAART rather than monotherapy is recommended ...
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A Novel Genetic Pathway of Human Immunodeficiency Virus Type 1 Resistance to Stavudine Mediated by the K65R Mutation
... The K65R mutation has been previously associated with emergence of resistance to tenofovir, ddC, and abacavir in vitro and confers cross-resistance to ddI and 3TC (7, 14, 43, 45). Despite this association, the prevalence ...
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HIV, antiretroviral therapy, and tuberculosis : outcomes in Johannesburg, South Africa
... of d4T when those drugs are available (Bolhaar and Karstaedt 2007); the recommendation for TDF receives preliminary further support from a recent conference report on long-term safety of TDF in Central and South ...
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cART prescription trends in a prospective HIV cohort in rural Tanzania from 2007 to 2011
... However, stavudine based combinations were still the most used overall by the end of the year 2011 because 90% of patients who initiated therapy containing stavudine before the update of guidelines in 2009 ...
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High prevalence and low cure rate of tuberculosis among patients with HIV in Xinjiang, China
... testing; D4T: Stavudine; EFV: Efavirenz; ELISA: Enzyme-linked immunosorbent assay; EPTB: Extra-pulmonary tuberculosis; HIV: Human immune deficiency virus; IPT: Isoniazid preventive therapy; IVDU: ...
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Provision and continuation of antiretroviral therapy during acute conflict: the experience of MSF in Central African Republic and Yemen
... worker; D4T: Stavudine; HIS: Health information system; HIV: Human immunodeficiency virus; HTC: HIV testing and counselling; IPD: Inpatients department; M&E: Monitoring and evaluation; MOH: Ministry of ...
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UK national clinical audit: management of pregnancies in women with HIV
... DOCX 130 kb Abbreviations ART: Antiretroviral therapy; BHIVA: British HIV Association; D4T: Stavudine; DDI: Didanosine; MDT: Multidisciplinary team; MTCT: Mother to child transmission; N[r] ...
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