Stem/progenitor cell
Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration
... mesenchymal stem cell; HRP: horseradish peroxidase; iPSC: induced pluripotent stem cell; LCI: live cell imaging; LMNA: lamin A gene; MDSPC: muscle-derived stem/progenitor ...
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Progress of stem/progenitor cell based therapy for retinal degeneration
... embryonic stem cells (hESCs) With an increasing understanding of the pluripotent nature of ESCs, a number of labs worldwide have estab- lished hESC derivation and culture protocols ...
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Sox1 marks an activated neural stem/progenitor cell in the hippocampus
... which cell types were being marked in the lineage tracing experiments, we co-stained sections from the hippocampus of triple transgenic mice with anti-GFP and markers for late progenitors/neuroblasts, neurons and ...
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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
... flow, cell proliferation and differentia- tion, and stem cell regeneration (Glaser et ...through cell surface re- ceptors (Rossi et ...
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Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis
... Mesenchymal stem cells (MSCs) can be recruited to the tumor microenvironment and are known as tumor- associated ...cancer stem cells ...stromal progenitor cells (OCSPCs) (epithelial-like and ...
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The regulation of haemopoietic stem cell and progenitor cell proliferation by humoral factors
... into lethally irradiated the spleens uptake of 5 days 7x105normal bone grafted mice previously with 15 fetal liver or day marrow gestational murine age Comparison incubated of mice injec[r] ...
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Cell lineage branching as a strategy for proliferative control
... With stem cells able to make only two choices at each division, negative regulation of one of them implies positive regulation of the ...But stem and progenitor cells could have other ...different ...
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Gene expression signatures of breast cancer stem and progenitor cells do not exhibit features of Warburg metabolism
... Nearly a century has elapsed since Otto Warburg ob- served that cancer cells preferentially utilize “aerobic gly- colysis” (i.e., Warburg metabolism). Recent advances in understanding the role of CSCs in the propagation ...
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Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise
... other progenitor cell types, MPCs share properties of both stem cells and mature ...of cell surface markers, cell adhesion molecules, and differ- entiation potential (Figure ...
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Hepatitis C Virus-Induced Cancer Stem Cell-Like Signatures in Cell Culture and Murine Tumor Xenografts
... of stem cell-related ...hepatic progenitor cell-related proteins using GS5 and FCA4 cell lines (7, 14, ...hepatoma cell line that permits efficient replication of ...hepatoma ...
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Sex Steroids and Stem Cell Function
... mesenchymal stem cells (MSCs) and endothelial progenitor ...endothelial progenitor cells to the ischemic myocardium and enhance neovascularization at the ischemic border ...endothelial ...
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Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells.
... eMPC, embryonic mammary progenitor cell; MSC, mesenchymal stem cell. eMPCs have lactogenic potential[r] ...
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Potential role of stem cells in management of COPD
... by stem cells from endogenous and exogenous sources is a promising therapeutic ...resident stem and progenitor cell niches within the lung, the contribution of mesenchymal stem cells to ...
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Pim1 kinase regulates c-Kit gene translation
... Our current study demonstrates an important role of Pim1 kinase in the regulation of c-Kit in murine HSPCs and in human megakaryoblastic leukemia cell line. Our results suggest that this regulation occurs at ...
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Emerging options for the management of age-related macular degeneration with stem cells
... projects, stem cell therapy has shown promise in restoring some visual function to AMD ...of stem cell is best suited to treating AMD patients? How much visual function can be restored? Are ...
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ALDH1A1-overexpressing cells are differentiated cells but not cancer stem or progenitor cells in human hepatocellular carcinoma
... cancer stem cell marker in several human ...cancer stem cell marker in ...cancer stem cell markers in ...cancer stem cells in ...
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Multipotent (adult) and pluripotent stem cells for heart regeneration: what are the pros and cons?
... BM-derived stem cells are able to trans-differentiate into various cell types, including neurons, hepatocytes, skeletal muscles and cardiomyocytes under appropriate culture conditions ...of cell ...
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Transplanted progenitors generate functional enteric neurons in the postnatal colon
... This is the first study to report the electrophysiological prop- erties of neurons generated from neural progenitor cells trans- planted into the gut. During ENS development, some cells express pan-neuronal ...
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Cusan, Monica (2012): Studie über das leukämogene Potential der Hoxb4-DeltaProlin Mutante in einem murinen Knochenmarkstransplantationsmodell und den Effekt der Hemmung von Histondeacetylasen in vitro und in vivo. Dissertation, LMU München: Medizinische Fakultät
... Chromosomal aberrations are a common finding in many cancers and their occurrence correlates with the biology and the progression of the tumor. In the solid cancers the diagnosis is made relatively late in their ...
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Regulation of centrosome movements by Numb and the Collapsin Response Mediator Protein during Drosophila sensory progenitor asymmetric division
... pI cell division by imaging pI cells expressing the pericentriolar marker GFP::Centrosomin (GFP::Cnn) (Megraw et ...asymmetric cell division, we observed that the two centrosomes of the dividing pI have a ...
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