Steroid-resistant
Difference of Vitamin D and Interleukin-6 Levels in Children with Steroid- Resistant, Steroid-Sensitive and Idiopathic Nephrotic Syndrome
... in steroid resistant nephrotic syndrome (SRNS), steroid sensitive (SSNS), and idiopathic nephrotic syndrome ...with steroid resistance (Spearman correlation test, p = ...with steroid ...
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Predictive urinary biomarkers for steroid-resistant and steroid-sensitive focal segmental glomerulosclerosis using high resolution mass spectrometry and multivariate statistical analysis
... which are urinary glycoproteins associated with chronic kidney disease [24]. CUBN (Cubilin) is highly expressed in the renal proximal tubule and the visceral yolk sac [25] and other tissues. Cubilin was shown to be an ...
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Steroid resistant asthma Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
... as steroid sensitive (SS) if their morning FEV1 increased > 30% after a 1-wk course of oral prednisone 20 mg twice daily and steroid resistant (SR) if they failed to increase > ...
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Treatment Strategies for Childhood Steroid- Resistant Nephrotic Syndrome
... Nephrotic syndrome (NS) is a common childhood kidney disease caused by impaired glomerular function, characterized by protein leakage from the blood to the urine through the glomeruli, resulting in proteinuria, ...
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Cellular mechanisms underlying steroid-resistant asthma
... severe steroid-resistant AAD (SSRAAD), we induced infections in allergic mice after AAD was initially established, to model the human ...to steroid treatment, mice were administered the ...
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Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid sensitive and steroid resistant patients with systemic lupus erythematosus
... of steroid resistance, but the amount of GR in cells changes in different pathological states ...vitro steroid response in children with acute lymphoblas- tic leukaemia ...
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Relative safety of steroid sparing agents in frequently relapsing, steroid dependent and steroid resistant nephrotic syndrome in pediatric patients
... (FRNS), steroid-dependent nephrotic syndrome (SDNS) and steroid resistant nephrotic syndrome (SRNS) steroids are usually ...of steroid dependency and avoid steroid toxicity, several ...
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Cyclosporine A and steroid therapy in childhood steroid-resistant nephrotic syndrome
... The management of steroid-resistant nephrotic syndrome (SRNS) remains a clinical problem. Several treatment modalities have been tested, including high- dose corticosteroids, cyclophosphamide, cyclosporine ...
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NPHS2 Gene Mutation and Polymorphisms in Indonesian Children with Steroid Resistant Nephrotic Syndrome
... standard steroid treatment with no remission [4]. Steroid-resistant nephrotic syndrome accounts about 10% - 15% of nephrotic syndrome in children and tends to progress to end stage-renal disease ...
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A 17-Year-Old With Steroid-Resistant Nephrotic Syndrome
... patients, respectively. The clinical presentation of Hodgkin lymphoma– associated INS is the same as classic INS. The diagnosis of Hodgkin lymphoma should be considered when patients have atypical features, including ...
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Advillin acts upstream of phospholipase C ϵ1 in steroid resistant nephrotic syndrome
... We describe how AVIL mutations result in a defective PMR as an intermediate phenotype of SRNS and elucidate the role of EGF signaling, PLCE1 recruitment by AVIL, IP3 and DAG generation b[r] ...
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Efficacy and safety of cyclosporine a for patients with steroid-resistant nephrotic syndrome: a meta-analysis
... CI: Confidence intervals; CR: Complete remission; CsA: Cyclosporine A; M- H: Mantel-Haenszel; MMF: Mycophenolate mofetil; NS: Nephrotic syndrome; OR: Odds ratio; P/NT: Placebo/nontreatme[r] ...
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Steroid-resistant nephrotic syndrome: past and current perspectives
... to steroid therapy as a guide to determining steroid ...true steroid resistance and noncompliance with steroid ...of steroid resistance is met in a young patient ( < 2 years old), ...
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Mycophenolate Mofetil Following Rituximab in Children With Steroid-Resistant Nephrotic Syndrome
... excellent steroid- sparing effect of rituximab against TABLE 1 Baseline Characteristics of Patients According to Outcome at 3 Months After Completion of Initial Rituximab Course (n = ...
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Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases
... Treatment with glucocorticoids offers quick symptom- atic relief and shortens the severity and duration of gastrointestinal, joint, and cutaneous symptoms [1, 14] Steroids are often used[r] ...
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Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD
... Chronic Obstructive Pulmonary Disease (COPD) is characterized by an abnormal inflammatory response of the lungs to, mostly, cigarette smoke [1]. This response is considered abnormal because, it is enhanced with re- spect ...
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Relationship of Childhood Idiopathic Nephrotic Syndrome with Asthma, Hypertension, Complement C3, Urinalysis
... had steroid resistant nephrotic syndrome (SRNS) leveled as group B and 24 were steroid sensitive nephrotic syndrome (SSNS) leveled as group C, in SSNS group 11 children had FRNS +SDNS, (Group C1) and ...
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Level Of 25(OH)D Serum, Expression of Interleukin 4 And Glucocorticoid Receptor of Mononuclear Cell In Steroid Resistance Nephrotic Syndrome Children
... In this study, lower expression of IL-4 in NS groups might be caused by administration of glucocor- ticoid and cytostatic drugs. The subject included in this study has been a routine visit to pediatric nephrology ...
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Evidence-based guideline update: Plasmapheresis in neurologic disordersReport of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
... of steroid-resistant exacerbations in relapsing forms of MS, and for neuropathy associated with immunoglobulin A or immunoglobulin G gammopathy, based on at least one Class I or 2 Class II studies (Level ...
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Abstract
... The pathogenesis of FSGS is not fully clari− fied [1], but injury of glomerular epithelial cells (podocytes), probably by circulating vascular per− meability factor(s) (VPF), possibly a lymphokine or cytokine (product of ...
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