Subacute sclerosing panencephalitis
Subacute sclerosing panencephalitis A case report
... Subacute sclerosing panencephalitis A case report Med J Malaysia Vol XXXIV No 4 June, 1980 SUBACUTE SCLEROSING PANENCEPHALITIS A CASE REPORT w c TlNG c T TAN N C GONG INTRODUCTION Subacute sclerosing[.] ...
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Teaching Video NeuroImages: Slow periodic myoclonus in subacute sclerosing panencephalitis and fulminant Wilson disease
... Slow periodic myoclonus is a well-recognized phenotype of fulminant subacute sclerosing panencephalitis (video 1). 1 This distinctive phenotype has not been previously recognized in another rapidly ...
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Early and Late State Subacute Sclerosing Panencephalitis: Chemical Shift Imaging and Single Voxel MR Spectroscopy
... Subacute sclerosing panencephalitis (SSPE) is a pro- gressive neurologic disorder of childhood and early adolescence (1). The diagnosis is based on clinical findings, EEG results, and the titer of ...
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The F Gene of the Osaka-2 Strain of Measles Virus Derived from a Case of Subacute Sclerosing Panencephalitis Is a Major Determinant of Neurovirulence
... occasions, causes subacute sclerosing panencephalitis (SSPE). SSPE is a fatal degenerative disease caused by persistent MV infection of the central nervous system (59). On rare occasions, MV has been ...
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Mutations Affecting Transcriptional Termination in the P Gene End of Subacute Sclerosing Panencephalitis Viruses
... Numerous mutations are found in subacute sclerosing panencephalitis (SSPE) viruses, and the M gene is the gene most commonly affected. In some SSPE viruses, such as the MF, Osaka-1, Osaka-2, and ...
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Subacute Sclerosing Panencephalitis: Results of the Canadian Paediatric Surveillance Program and review of the literature
... Initial EEG demonstrated generalized 3 Hz spike wave and polyspike and wave. A subsequent EEG five months later showed marked abnormality with no normal rhyth- micity and intermittent projected activity consisting of ...
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Characterization of Virus-Specific RNAs from Subacute Sclerosing Panencephalitis Virus-Infected CV-1 Cells
... 962-968 Copyright 0 1973 American Society for Microbiology Characterization of Virus-Specific RNAs from Subacute Sclerosing Panencephalitis Virus-Infected CV-1 Cells Received for publica[r] ...
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Ophthalmic examination as a means to diagnose Subacute Sclerosing Panencephalitis: an optical coherence tomography and ultrawide field imaging evaluation
... An aberrant measles virus causes subacute sclerosing panencephalitis (SSPE). This disorder causes significant neurological morbidity and has a high mortality rate [1]. The eye is involved in up to ...
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The SI Strain of Measles Virus Derived from a Patient with Subacute Sclerosing Panencephalitis Possesses Typical Genome Alterations and Unique Amino Acid Changes That Modulate Receptor Specificity and Reduce Membrane Fusion Activity
... Subacute sclerosing panencephalitis (SSPE) is a fatal sequela associated with measles and is caused by persistent infection of the brain with measles virus ...
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Subacute sclerosing panencephalitis: case based review
... A seizure workup consisting of complete blood count (CBC), serum electrolytes, electroencephalogram (EEG), Magnetic resonance imaging (MRI) of the brain and lumbar puncture for cerebrospinal fluid (CSF) examination was ...
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Screening Random Peptide Libraries with Subacute Sclerosing Panencephalitis Brain-Derived Recombinant Antibodies Identifies Multiple Epitopes in the C-Terminal Region of the Measles Virus Nucleocapsid Protein
... Infectious and inflammatory diseases of the CNS are often characterized by a robust B-cell response that manifests as increased intrathecal immunoglobulin G (IgG) synthesis and the presence of oligoclonal bands. We ...
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Subacute sclerosing panencephalitis – current perspectives
... Abstract: Subacute sclerosing panencephalitis is a progressive neurodegenerative ...for subacute sclerosing panencephalitis to date, but it is preventable by ensuring that an ...
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Analysis of a Subacute Sclerosing Panencephalitis Genotype B3 Virus from the 2009-2010 South African Measles Epidemic Shows That Hyperfusogenic F Proteins Contribute to Measles Virus Infection in the Brain
... ABSTRACT During a measles virus (MeV) epidemic in 2009 in South Africa, measles in- clusion body encephalitis (MIBE) was identified in several HIV-infected patients. Years later, children are presenting with ...
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Cloning the Antibody Response in Humans with Chronic Inflammatory Disease: Immunopanning of Subacute Sclerosing Panencephalitis (SSPE) Brain Sections with Antibody Phage Libraries Prepared from SSPE Brain Enriches for Antibody Recognizing Measles Virus Antigens In Situ
... Standard immunological techniques have not revealed a vi- ral or cellular antigen that consistently reacts with MS OGBs. Recombinant antibody technology combined with phage dis- play offers a novel strategy to identify ...
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Subacute sclerosing panencephalitis: evaluation with CT and MR
... PURPOSE: To evaluate the progression of CT and MR changes of the brain in subacute sclerosing panencephalitis (SSPE) as a basis for assessing the effects of different types of therapy. METH- ODS: ...
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Epidemiologic Studies of Measles, Measles Vaccine, and Subacute Sclerosing Panencephalitis
... Epidemiologic Studies of Measles, Measles Vaccine, and Subacute Sclerosing Panencephalitis.. John F.[r] ...
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Functional analysis of matrix proteins expressed from cloned genes of measles virus variants that cause subacute sclerosing panencephalitis reveals a common defect in nucleocapsid binding.
... In this communication we show that the M proteins of three MV strains that cause acute infection Nagahata, Edmonston, and YN bind efficiently to the viral nucleocapsids whereas the M pro[r] ...
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Structural defect linked to nonrandom mutations in the matrix gene of biken strain subacute sclerosing panencephalitis virus defined by cDNA cloning and expression of chimeric genes.
... 1162-1173 0022-538X/89/031162-12$02.00/0 Copyright © 1989, American Society for Microbiology Structural Defect Linked to Nonrandom Mutations in the Matrix Gene of Biken Strain Subacute S[r] ...
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Multiple viral mutations rather than host factors cause defective measles virus gene expression in a subacute sclerosing panencephalitis cell line.
... UDEM2* Institut fur Molekularbiologie I, Universitat Zuirich, Honggerberg, 8093 Zurich, Switzerland,' and Departments of Cell Biology, Microbiology and Immunology, and Medicine, Albert E[r] ...
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Western blot analyses of measles virus antibody in normal persons and in patients with multiple sclerosis, subacute sclerosing panencephalitis, or atypical measles
... Comparing these two groups with the MLPI group, we found that the anti-H level in MLPI sera was low in both actual and relative terms and that the anti-P level was high, although the lat[r] ...
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