superparamagnetic iron oxide nanoparticle
Tissue Plasminogen Activator Binding to Superparamagnetic Iron Oxide Nanoparticle—Covalent Versus Adsorptive Approach
... to iron oxide nanoparticles for magnetic drug targeting to blood clots could provide higher bioavail- ability and could help to overcome the drawbacks caused by this high ...
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Whole body tracking of superparamagnetic iron oxide nanoparticle-labelled cells – a rheumatoid arthritis mouse model
... Particle uptake is quantified by measuring the total intracellular iron (Fe) content. This value is dependent upon on a number of factors including particle size, surface charge, labelling protocol and the rate of ...
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The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross Presentation
... In the development of adaptive immunity to tumours and most infectious pathogens, professional APCs, such as DCs, are capable of presenting exogenous antigens to CD8 positive cytotoxic T lymphocytes in a pivotal process, ...
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Therapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review
... SPION, superparamagnetic iron oxide nanoparticle; FLASH, fast low-angle shot; h, hours; ST, slice thickness; TR, repetition time; Te, echo time; Ref, reference; d, day; MF, magnetic field; ...
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Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model
... of superparamagnetic iron oxide nanoparticle (SPION) samples, the BBB was first examined and confirmed by an immunofluorescent stain and evaluating the transendothelial electrical ...
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Drug delivery to atherosclerotic plaques using superparamagnetic iron oxide nanoparticles
... The authors thank Dr Marina Pöttler, Bianca Weigel, and Julia Band for help with animal experiments, Eveline Schreiber for help with nanoparticle preparation, and Hatice Genç for performing nanoparticle ...
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Quantification of the internalization patterns of superparamagnetic iron oxide nanoparticles with opposite charge
... single nanoparticle detection and tracking is hard to realize by conventional confocal mi- croscopy the relevance of trajectory correlation is quite low, although the results seem to bear good prospects due to the ...
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Applications of Magnetic Nanoparticles as Contrast Agents in MRI: Recent Advances and Clinical Challenges
... failure. Iron oxide nanoparticles are a good alternative for these ...the iron oxide is used as contrast agent, because this factor strongly depends on the size of ...and ...
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A Review of Magnetic Particle Imaging and Perspectives on Neuroimaging
... of superparamagnetic iron oxide nanopar- ticles modeled by the Langevin theory, with the ability to track and quantify nanoparticle concentrations without tissue background ...
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Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)
... the nanoparticle internalization by tumor cells, a flow cytometer equipped with a coherent red solid state diode (635 nm), uniphase argon laser (488 nm), side scatter detector (SSD), and forward scatter detector ...
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Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors
... Notes: (A) confocal microscopy images of the c6 cells after 24 hours of incubation with phosphate buffered saline, sPION (150 µg/ml), and sPION–egF conjugates (150 µg/ml). Nuclei were stained with DAPI (blue). Magnetic ...
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Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine
... magnetic iron oxide, directs nucleation, controls growth, and sterically stabilizes the resulting 5-nm superparamagnetic iron ...prepare superparamagnetic polymeric nanoparticles by ...
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Scherer, Franz (2006): Establishment of magnetofection - a novel method using superparamagnetic nanoparticles and magnetic force to enhance and to target nucleic acid delivery. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... iron-boron (Nd-Fe-B) magnet used in all our experiments influences cell physiology in a manner that enhances transfection and/or reporter gene expression. It is well documented that low frequency electromagnetic ...
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Evaluation of iron oxide nanoparticle biocompatibility
... Figure 4 effect of nanoparticles on endothelial cell viability. A) The number of viable cells was measured by 3-(4,5-dimethylthiazol-2-yl) diphenyltetrazolium bromide (MTT) when exposed to nanoparticles (NP) at the ...
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Magnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium
... intracellular iron particles. To determine the attenuation of iron content in cells over time, labeled MSCs continued to be cultured in medium, and the iron content of the cells was quantified every ...
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Gold-functionalized magnetic nanoparticles restrict growth of <em>Pseudomonas aeruginosa</em>
... P. aeruginosa obtained from the Polish Collection of Micro- organisms (Institute of Immunology and Experimental Therapy, Wrocław, Poland) was grown overnight at 37 ° C in Luria- Bertani broth (Oxoid, Basingstoke, UK) ...
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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
... of iron oxide are divided into classes based on their size (Table ...small superparamagnetic particles of iron oxide (USPIOs) that consist of nanoparticles with a diameter of <50 nm ...
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One-Pot Facile Synthesis of New 1, 2, 4-Triazolidine Derivatives Using Sodium Borohydride and Fe3O4 Magnetic Nanoparticles (MNPs)
... Recently, superparamagnetic iron oxide nanoparticles (SPIONs) have been intensively investigated because of their super paramagnetic properties, excellent catalytic activity in organic synthesis, ...
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Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers
... of iron with transition metal ions such as copper, cobalt, nickel, and manganese, are known to exhibit super- paramagnetic properties and also fall into the category of ...
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Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
... On the other hand, about 1–4 months were necessary, respectively, to completely clear 10 (Figure S1) or 50 mg/kg (yellow rectangles in Figure 3) of cat-USPIOs from the liver, the organ responsible for detoxification of ...
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