Sweat Chloride
Buccal Cell DNA Mutation Analysis for Diagnosis of Cystic Fibrosis in Newborns and Infants Inaccessible to Sweat Chloride Measurement
... Patients. Between November 1, 1992, and April 30, 1994, 28 newborns and infants under 12 months of age at risk for CF had CFTR DNA mutation analysis performed because a sweat chloride (SC) value could not ...
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The Silver Electrode Method for Rapid Analysis of Sweat Chloride
... The Silver Electrode Method for Rapid Analysis of Sweat Chloride.. A new sweat test which uses a standard3[r] ...
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Quality of sweat test (ST) based on the proportion of sweat sodium (Na) and sweat chloride (Cl) as diagnostic parameter of cystic fibrosis: are we on the right way?
... It is assumed that quality of the ST can be assessed by concentrations of sweat sodium and sweat chloride; however, our study showed a great number of poor qual- ity sweat tests. The quality ...
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Negative Effects of Oral Fatty Acid Supplementation on Sweat Chloride in Cystic Fibrosis
... Negative Effects of Oral Fatty Acid Supplementation on Sweat Chloride in Cystic. Services[r] ...
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Pulsed direct and constant direct currents in the pilocarpine iontophoresis sweat chloride test
... of substance delivery proportionally to the time of appli- cation of the impedance. This fact can be minimized by the use of PDC, which is delivered periodically [37,38]. During the phase without stimulation, the skin ...
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Sweat Chloride Concentrations in Infants Homozygous or Heterozygous for F508 Cystic Fibrosis
... A total of 725 infants were evaluated in this study, including 481 with newborn screening test results positive for CF; the other infants had been referred to the University of Wisconsin[r] ...
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SWEAT CHLORIDE CONCENTRATION IN CHILDREN WITH ALLERGY AND WITH CYSTIC FIBROSIS OF THE PANCREAS
... Sixty-six subjects from the Pediatric and Allergy Services of Walter Reed General Hospital were divided into the following study groups: Group I: six children with cystic fibrosis; Group[r] ...
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Meconium Peritonitis and Increasing Sweat Chloride Determinations in a Case of Familial Progressive Intrahepatic Cholestasis
... tic fibrosis; they noted two infants with meconium peritonitis who had no signs of intestinal obstruc- tion, one of these had cystic fibrosis but the other did not. Donrnson et al7 have [r] ...
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Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis
... We enrolled adult subjects with CF who had at least one G551D or R117H allele in two prospective observational studies at a single CF center, the National Referral Centre for Adult Cystic Fibrosis. Inclusion criteria ...
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Targeting a genetic defect: cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis
... CFTR correctors are designed to increase the amount of func- tional CFTR protein delivered to the cell surface. Correctors have been used to target Class II mutations such as F508del [47, 48]. One such molecule, VX-809, ...
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PubMedCentral-PMC5148144.pdf
... of Sweat Chloride Concentration in the CF Population To quantify the relative contribution of CFTR mutations, and other genetic and environmental factors to sweat chloride variation, we ...
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Factors affecting the growth of infants diagnosed with cystic fibrosis by newborn screening
... Results: Complete data were available on 129 children. 113 (88%) were pancreatic insufficient (PI) and 16 (12%) pancreatic sufficient (PS). Mean birth weight (z score) was 3.17 kg ( − 0.32). There was no significant ...
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A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators
... ABSTRACT In this article we analyse the current authorised treatments and trends in early drug development for cystic fibrosis (CF) in the European Union for the time period 2000 – 2016. The analysis indicates a ...
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Summer Day/Night Gender Differences in Serum Total Antioxidant Capacity as a Methodological Pitfall in Human Antioxidant Research
... Sweat chloride test is the gold standard to diagnose CF and to monitor patients during molecular therapies, where accurate results are required. Recent papers identify different issues about laboratories ...
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Atypical cystic fibrosis
... normal sweat chloride ...through sweat chloride testing with or without genetic ...elevated sweat chloride levels; sweat chloride testing, nasal potential ...
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Increased Prevalence of Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator in Children With Chronic Rhinosinusitis
... Clinical data on the 58 patients was notable for the occurrence in 2 patients of recurrent Pseudomonas aeruginosa infections. The first, a 6-year-old white boy, presented with recurrent rhinosinusitis requir- ing ...
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Could a defective epithelial sodium channel lead to bronchiectasis
... the sweat glands and in the nasal ...silver/silver chloride electrodes connected to a high impedance volt- meter, one electrode being in contact with the inferior sur- face of the nasal inferior turbinate ...
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ABNORMAL ELECTROLYTE COMPOSITION OF SWEAT IN CYSTIC FIBROSIS OF THE PANCREAS
... Abdominal sweat chloride in 43 patients with cystic fibrosis of pancreas (50 determinations) and 50 controls... Presbyterian Hospitals with the following specifically excluded: patients [r] ...
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When and how ruling out cystic fibrosis in adult patients with bronchiectasis
... 43]. Sweat test may be not conclusive and intermediate results may be due to residual CFTR functionality as well as environ- mental factors ...reports sweat chloride concentrations ap- peared to ...
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Intestinal current measurement versus nasal potential difference measurements for diagnosis of cystic fibrosis: a case–control study
... criteria, sweat chloride values distinguish patients with CF from healthy controls (p < ...mean sweat chloride differed between CF-PS and CF-PI patients (p = ...
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