synaptic plasticity
BAI1 regulates spatial learning and synaptic plasticity in the hippocampus
... factors that regulate this feature are incompletely understood. Here, we demonstrated that mice lacking brain-specific angiogenesis inhibitor 1 (BAI1) have severe deficits in hippocampus-dependent spatial learning and ...
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Protective effects of Nigella sativa on synaptic plasticity impairment induced by lipopolysaccharide
... the amplitude and slope of fEPSP in LPS group compared to the control group. This finding indicates that LPS attenuated synaptic plasticity and reduced LTP induction in the hippocampus of rat in current ...
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Role for astroglial α1 adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex
... of synaptic plasticity in the neocortex:long-term potentiation (LTP) of neocortical excitatory synaptic potentials can be abolished by the selective α 1-adrenoreceptor antagonist ...of ...
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Caspases in synaptic plasticity
... in synaptic plasticity, inde- pendent of neuronal cell ...lasting synaptic plasticity in hip- pocampal ...of synaptic strength, but the mechanism of how caspase-3 controls AMPA receptor ...
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Borna Disease Virus Infection Impairs Synaptic Plasticity
... Signaling by extracellular signal-regulated kinase (ERK)1/2 has been shown to be essential for the development of a long- lasting increase in neuronal network activity, in particular fol- lowing exposure to bicuculline ...
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Structure-Function Relationships Of Rna And Protein In Synaptic Plasticity
... expressed molecules. In this thesis, I introduce two novel computational methods for genome-scale structure- function analysis and demonstrate their application to identifying RNA and protein structures involved in ...
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MSK1 regulates homeostatic and experience dependent synaptic plasticity
... modulate synaptic strength underpins synaptic plasticity, learning and memory, and adaptation to sensory ...of synaptic adaptation in directing, reinforcing, and revising the behavioral ...
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Fragile X mental retardation protein and synaptic plasticity
... of synaptic plasticity associated with learning and ...in synaptic strength can be induced by a variety of manipulations and their expression mechanisms are ...of plasticity requiring local ...
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Lithium rescues synaptic plasticity and memory in Down syndrome mice
... hippocampal synaptic plasticity in Ts65Dn mice, thereby ruling out the involve- ment of other acute effects of lithium and further supporting the notion that functional neurogenesis is specifically involved ...
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Suppression of synaptic plasticity by fullerenol in rat hippocampus in vitro
... In the present study, we have shown that acute treatment with 5 μ M fullerenol suppressed short- and long-term synaptic plasticity, indicated by decreased PPF and LTP in hippocampal slices. Furthermore, the ...
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Intelligent Robot Based on Synaptic Plasticity and Neural Networks
... This Paper describes a model and an implementation of Spatio neural network paradigm for embedded microcontrollers with few bytes of memory and very low power consumption. The proposed model consists of an elementary ...
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Effects of PI3Kβ overexpression in the hippocampus on synaptic plasticity and spatial learning
... impaired synaptic plasticity and reduced behavioral ...in synaptic plasticity and hippocampus- dependent behavioral tasks we overexpressed p110 γ , the catalytic subunit of PI3K γ , in the ...
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Endogenous acetylcholine modulates synaptic plasticity in the hippocampus in vivo
... The stim ulation protocol used to induce LTD can also reverse the potentiated state o f LTP, i.e. depotentiation, which has some sim ilarities and disparities with LTD (W ager & A lger 1996; Kemp & Bashir 2001). ...
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Emotional enhancement of memory: how norepinephrine enables synaptic plasticity
... modulate synaptic plasticity in other neural circuits besides the hippocampus and ...associative plasticity at the parallel fiber synapses ...affecting synaptic plasticity by decreasing ...
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Activated Caspase 3 and Neurodegeneration and Synaptic Plasticity in Alzheimer’s Disease
... In Alzheimer’s disease (AD) there is a loss of neurons in different areas of the brain, including hippocampus, temporal and frontal cortex. Molecular mechanism of neuronal death in AD is not clear. It seems that ...
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Probabilistic inference of short term synaptic plasticity in neocortical microcircuits
... Synaptic plasticity is thought to underlie learning and informa- tion processing in the ...Short-term plasticity (STP) refers to transient changes in synaptic efficacy, in the range of tens of ...
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Soft bound synaptic plasticity increases storage capacity
... There have recently been a number of studies on information storage and forgetting in synapses with a discrete number of states. The continuous synapses studied here have an equal or superior capacity, as they can always ...
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Transcranial magnetic stimulation, synaptic plasticity and network oscillations
... TMS seems to have several consequences that are not directly related to synaptic plasticity and neuronal excita- bility. Such effects are just starting to be examined experi- mentally. The results thus far ...
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MoL 2010 10: Temporal Binding by Short Term Synaptic Plasticity
... The next sections introduces a solution to the binding problem as pro- posed in [von der Malsburg, 1981]. This method uses the exact timing of spikes in a network of neurons to perform binding. Three implementations of ...
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Reinforcement determines the timing dependence of corticostriatal synaptic plasticity in vivo
... Because plasticity such as that shown here is dependent on both dopamine transmission and glutamatergic depolarization 33 , it is likely that these two simultaneous phasic, sensory-evoked afferent signals acted in ...
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