synaptonemal complex (SC)
Localization of Single- and Low-Copy Sequences on Tomato Synaptonemal Complex Spreads Using Fluorescence in Situ Hybridization (FISH)
... FISH, synaptonemal complex (SC) spreads (hypotonically spread pachytene chromo- somes) have several ...advantages. SC spreads (1) are comparatively free of debris that can interfere with probe ...
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Phylogenies of Central Element Proteins Reveal the Dynamic Evolutionary History of the Mammalian Synaptonemal Complex: Ancient and Recent Components
... the synaptonemal complex ...mammalian SC are conserved in metazoan ...the SC arose only once, but evolved dynamically during diversification of Metazoa ...
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The Puf RNA binding proteins FBF 1 and FBF 2 inhibit the expression of synaptonemal complex proteins in germline stem cells
... of synaptonemal complex (SC) genes and their ...the SC 3⬘ UTRs by MEME (see Materials and ...in SC 3⬘ UTRs from ...the SC 3⬘ UTRs (red asterisks in B) and in the fem-3 3⬘ UTR ...
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Drosophila Oocytes as a Model for Understanding Meiosis: An Educational Primer to Accompany “Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila”
... Unlike mitosis, in which the end result is a diploid daughter cell with equal chromosome content and genetic identity to its mother, the end result of meiosis is a unique haploid daughter cell, distinct from both sets of ...
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Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes
... During meiosis, specific events are required to promote genetic diversity and ensure the segregation of homolo- gous chromosomes. These events, including synapsis and meiotic recombination between homologous chro- ...
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Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila Oocytes
... The synaptonemal complex (SC) is an intricate structure that forms between homologous chromosomes early during the meiotic prophase, where it mediates homolog pairing interactions and promotes the ...
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In Vivo Analysis of Synaptonemal Complex Formation During Yeast Meiosis
... a synaptonemal complex (SC) forms between each pair of homologous chromosomes and is believed to be involved in regulating ...zygotene, SC assembly was initiated at foci that appeared ...
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Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans
... Synapsis involves the assembly of a proteinaceous com- plex, the synaptonemal complex (SC), between paired homologous chromosomes, and is essential for crossover re- combination (Bhalla and Dernburg ...
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Lateral Elements Inside Synaptonemal Complex-Like Polycomplexes in ndt80 Mutants of Yeast Bind DNA
... The synaptonemal complex (SC) keeps the synapsed homologous chromosomes together during pachy- tene in meiotic prophase I. Structures that resemble stacks of SCs, polycomplexes, are sometimes found ...
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Synaptonemal Complex Proteins of Budding Yeast Define Reciprocal Roles in MutSγ-Mediated Crossover Formation
... the synaptonemal complex (SC), but the functional relationship between SC and crossover recombination remains ...of SC proteins and successful crossing over, indicating that the ...
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Synaptonemal Complex Central Region Proteins Promote Localization of Pro-crossover Factors to Recombination Events During Caenorhabditis elegans Meiosis
... the synaptonemal complex (SC), a meiosis-specific structure that assembles between aligned ...the SC (SYP proteins) are essential to repair double-strand DNA breaks (DSBs) as ...the SC ...
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Synaptonemal complex protein 3 is associated with lymphangiogenesis in non small cell lung cancer patients with lymph node metastasis
... Synaptonemal complex protein 3 (SCP3) is a DNA- binding protein and a structural component of the syn- aptonemal complex, which mediates the synapsis or homologous pairing of chromosomes during human ...
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Normal Synaptonemal Complex and Abnormal Recombination Nodules in Two Alleles of the Drosophila Meiotic Mutant mei-W68
... with synaptonemal complex and the bi- are not necessarily precursor product (Powers and valent around it during meiosis) were originally identi- Smithies 1986; Smithies and Powers 1986; Carpenter fied ...
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Synaptonemal Complex Protein 3 Transcript Analysis in Breast Cancer
... The RNA transcript levels of the testis specific gene; Synaptonemal Complex Protein 3 was de- tected in breast cancer tumors and five breast cancer cell lines, where it should not be normally expressed. The ...
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Eichinger, Christian (2009): Coordination of synaptonemal complex formation and pachytene checkpoint signaling in meiosis. Dissertation, LMU München: Fakultät für Biologie
... Synaptonemal complex formation was studied (Scherthan et al., 2007) by spinning disk microscopy. An ANDOR/TiLL iMIC CSU22 spinning disk confocal microscope with a 100x 1.45NA objective lens (Olympus) was ...
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Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila
... Previous studies have also shown that SC disruption can lead to reduced DSB formation (Mehrotra and McKim 2006). To assay the number of DSBs, we used a monoclonal antibody recognizing the phosphorylated form of ...
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Finkbeiner, Martin G. (2003): Ssp1p is a lipid binding protein involved in shaping of the prospore membrane during meiosis in S. cerevisiae. Dissertation, LMU München: Fakultät für Biologie
... In a Double Holliday junction the two initial helices are held together by reciprocal exchange of two of their four strands. Double Holliday junction resolution during Pachytene requires the cleavage of the two strands ...
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Female Meiosis: Synapsis, Recombination, and Segregation in Drosophila melanogaster
... the synaptonemal complex (SC). When fully assembled, the SC also plays a critical role in maintaining homolog synapsis and in facilitating the maturation of double-strand breaks (DSBs) into ...
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SYNAPTONEMAL COMPLEX AND RECOMBINATION NODULES IN WILD-TYPE DROSOPHILA MELANOGASTER FEMALES
... Spherical recombination nodules (the unqualified recombination nodules of CARPENTER 1975b) in Drosophila correlate closely with reciprocal exchange events in number per nu[r] ...
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A conditional allele of the Saccharomyces cerevisiae HOP1 gene is suppressed by overexpression of two other meiosis-specific genes: RED1 and REC104.
... The HOPI gene of Saccharomyces cerevisiae is believed to encode a protein component of the synaptonemal complex, the structure formed when homologous chromosomes syn[r] ...
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