T-bet/GATA-3
Different Expressions of Specific Transcription Factors of Th1 (T-bet) and Th2 cells (GATA-3) by Peripheral Blood Mononuclear Cells From Patients With Multiple Sclerosis
... the T-bet/GATA-3 ex- pression ratio in non-stimulated, MOG-stimulated, and PHA-stimulated PBMCs of patients with MS were high- er than those of the same cell cultures from the healthy ...the ...
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Clinical significance of T bet, GATA 3, and Bcl 6 transcription factor expression in bladder carcinoma
... namely T-bet, GATA- 3, and Bcl-6, were determined by quantitative real- time reverse-transcriptase PCR ...the T-bet, GATA-3, Bcl-6, and L32 genes are described in ...
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Immunohistochemical expression of Foxp3, T-bet, GATA-3, MAK387 and Bcl-2 in brain tumors (meningioma and glioma) of Iraqi patients
... to GATA- 3, T-bet was also examined for the first time in BTs, and its expression was distributed for both tumor types at all scores and the highest score was ...effector T cell genes, ...
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Changes of T-lymphocyte subpopulation and differential expression pattern of the T-bet and GATA-3 genes in diffuse large B-cell lymphoma patients after chemotherapy
... on T-cell differentiation. T-bet, one of the specific transcription factors, is vital in all three important differentiation pathways of Th1 cells, ...of T-bet, which intensely ...
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Differential Expression of Interleukin-4 (IL-4) and IL-4δ2 mRNA, but Not Transforming Growth Factor Beta (TGF-β), TGF-βRII, Foxp3, Gamma Interferon, T-bet, or GATA-3 mRNA, in Patients with Fast and Slow Responses to Antituberculosis Treatment
... Quantitative real-time PCR. RNA was isolated from ex vivo blood samples by using mRNA isolation kits for blood and bone marrow (Roche kit). The isolation was done according to the manufacturer’s instructions. The ...
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Evaluation of mRNA Expression of the Transcription Factors of Th1 and Th2 subsets (T- bet and GATA-3) in Periodontal Health and Disease
... the GATA family of transcription ...that GATA-3 dictates Th2 differentiation by regulating Th2 cytokine production through binding to the IL-4 locus that encompasses the IL-4, IL-5 and IL-13 ...of ...
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β-Caryophyllene causes remyelination and modifies cytokines expression in C57BL/6 mice with experimental autoimmune encephalomyelitis
... and GATA-3), and remyellination in C57BL/6 mice induced for experimental autoimmune encephalomyelitis (EAE), the model for studying pathogenesis and new therapies for multiple ...IL-17, T-bet, ...
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Distinct expression profiles of TGF β1 signaling mediators in pathogenic SIVmac and non pathogenic SIVagm infections
... Six Chinese rhesus macaques (M. mulatta) and 6 AGMs (C. sabaeus from Senegal) were infected intravenously with SIVmac251 and SIVagm.sab92018, respectively [1]. The Central Committee for Animals at Institut Pasteur, ...
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Effect of Sijunzi decoction combined with nutritional support after gastric cancer surgery on the stress inflammatory response and immune response
... and 3 d after surgery, 1-2 mL of peripheral venous blood was collected from the two groups of patients at 7:00-8:00 am and divided into two, one was directly used to incubate the fluorescent antibody of CD3, CD4, ...
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Original Article BMSCs-induced CD45RB dendritic cells suppress T cell activity
... the T-bet, GATA-3, RORγt, Foxp3 mRNA content of T cells co-incubated with or without these DCs were determined by qPCR using Revert Aid First Strand cDNA Synthesis Kit (Thermo, USA) and ...
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Expression of Th1 and Th2 Cytokine and Associated Transcription Factors in Peripheral Blood Mononuclear Cells and Correlation with Disease Severity
... by T helper (Th) 1 cells and dysfunction of Th2 cells ...CD4(+) T lymphocytes and systemic and local overexpression of the pro-inflammatory cytokines IFN-γ, IL-6, and tumor necrosis factor alpha (TNF- α) ...
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Original Article T-box transcription factor 21 expression in breast cancer and its relationship with prognosis
... Purpose: T-box transcription factor 21 (T-bet) is a key lineage-defining transcription ...between T-bet expression in primary tumors and prognosis of breast ...Methods: ...
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A comprehensive analysis of bet, bet xt, bet fi and bet ng indices using the joint symmetric and asymmetric arma garch models
... above 3 indicates a probability distribution with fat-tails ...is BET-FI ( . . = 2.310), followed by BET ( ...is BET-NG ( . . = 1.693). We can also see that for BET and BET-FI ...
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Single-Cell Gene-Expression Analysis by Quantitative RT-PCR
... A potentially important difference between the cell types we surveyed and cardiomyocytes is the post-mitotic lifetime of the cells. Granulocyte and naïve B and T cell populations in the peripheral blood are ...
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T bet expression in CD8+ T cells associated with chronic hepatitis B virus infection
... 2 – 3 × 10 6 PBMCs were stained with MHC-I pentamers according to the manufacturer’s instructions. After stain- ing with viability dyes and antibodies specific for surface markers, cells were fixed with ...
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The bet on a bald
... Abstract. A fixed company of players observes a person selected from a fixed queue. After each observation, players are asked to bet the dollar secret from others, either on the fact that person is bald, or on what ...
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Linking obesity with type 2 diabetes: the role of T-bet
... Th1 T cells, induce insulin resistance in response to environmental factors, such as dietary lipids, doing so via the action of immune mediators, including cytokines, such as IFN γ ...that ...
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Characterization Of Human T-Bet-Expressing B Lymphocytes And Their Role In The Hiv Immune Response
... Plasma cells and their immature precursors plasmablasts (collectively termed antibody secreting cells (ASCs)) represent the terminal differentiation state of the B cell lineage and function to constitutively produce and ...
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T-bet Is Required for Protection against Vaccinia Virus Infection
... Vaccinia virus (VV) is a large DNA virus and a member of the Orthopoxvirus genus in the Poxviridae family. VV has been used as an effective vaccine against variola virus, which is the cause of smallpox. VV has also been ...
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Eomesodermin and T-bet mark developmentally distinct human natural killer cells
... when T-bet and Eomes are expressed, and to facilitate identification of rare NK cell populations from fetal tissues, we enriched for NK cells by negative selection using the Human NK Cell Isolation Kit ...
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