T-cell lymphoma/leukemia
<p><em>BRAF</em> V600E-positive monomorphic epitheliotropic intestinal T-cell lymphoma complicating the course of hairy cell leukemia</p>
... Hairy cell leukemia (HCL) is an uncommon B-cell chronic lymphoproliferative disorder whose pathogenesis and recurrence are strictly dependent on the presence of the BRAF V600E ...inal ...
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Identification of the human T cell lymphoma virus in B cell lines established from patients with adult T cell leukemia
... adult T cell ...expressed T cell markers, these two cell lines expressed B cell antigens and Ig light chains (kappa on CF-2, lambda on ...Human T cell ...
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Combination of Haemoglobinopathy and Haemopathy —(Adult T Cell Lymphoma/Leukemia and Sickle Cell Disease: A Rare Case of Disease Observed in the Adult Referral Center of Sickle Cell Disease (CRD A) in Martinique
... Authors report a case of beta thalassemia combined with hematological ma- lignant (ATLL) in a 40-year-old female, cashier screened HTLV-1 positive; followed since her 10 years old for the account of thalasso-sickle ...
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Human T-Lymphotropic Virus-1 Associated with Adult T-Cell Lymphoma/ Leukemia and Generalized Expansion of Palatal and Jaw Bones: A Rare Case Report
... Generally, most individuals infected with HTLV- 1 are asymptomatic carriers; however, a few patients would present some conditions such as ATL/L or tropi- cal spastic paraparesis which is a chronic progressive ...
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Aggressive natural killer cell leukemia or extranodal NK/T cell lymphoma? a case with nasal involvement
... Third, the patient suffered many pathogenic manifes- tations aside from his nasal symptoms, including pan- cytopenia hepatosplenomegaly, lymphadenopathy and sternal tenderness, all of which were observed when he first ...
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Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.
... In fact, the heterogeneity among HTLV-II strains from the Western Hemisphere was similar to that observed in HTLV-I and simian T-cell lymphoma/leukemia virus type I isolates from around [r] ...
10
Original Article Intravascular cytotoxic T-cell lymphoma presenting as hydrocele testis: a case report and review of the literature
... NK/T-cell lymphoma showed NK-cell pheno- type and negative for monoclonal TCR rear- rangement suggested they were NK-cell lym- phoma ...NK/T-cell lymphoma may be ...
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Collision Anaplastic Large Cell Lymphoma (T Cell/Histiocyte Rich) and Diffuse Large B Cell Lymphoma: A Pathologic and Clinical Evaluation
... lymphocytic leukemia (CLL) and invasive ductal carcinoma of the breast [1], T-cell lymphoma and squamous cell carcinoma of the lung [2], Hodgkin’s disease and metastatic breast or ...
6
Aggressive mature natural killer cell neoplasms: from epidemiology todiagnosis
... NK/T cell lymphoma, nasal type (NKTCL) [19], and aggressive NK-cell leukemia (ANKCL) [20] – and one provisional entity – chronic lymphoproliferative disorders of NK-cells (CLPD-NK) [21] ...
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Mogamulizumab for the treatment of adult T-cell leukemia/lymphoma
... Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell lymphoma caused by latent infection of human T-cell lymphotropic virus type ...stem cell ...
7
MYC as therapeutic target in leukemia and lymphoma
... antigen-dependent T-cell, the naïve B-cell moves to a fol- licle where it intensely proliferates to form a germinal ...producing cell (plasma cell) or as a memory B-cell ...
17
Altered expression of cell cycle regulators in adult T-cell leukemia/lymphoma patients
... To assess the HTLV-1 proviral load, PBMCs were isolated and DNA was extracted from PBMCs by DNA extraction kit (Cinnagen, Iran). Real-time PCR was performed by a Rotorgene Q Real-Time PCR machine (Qiagen, Germany) using ...
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Adult T-cell leukemia/lymphoma in the Caribbean cohort is a distinct clinical entity with dismal response to conventional chemotherapy
... Adult T-cell leukemia/lymphoma (ATLL) is a rare and aggressive disease caused by human T-cell lymphotropic virus type 1 that predominantly affects Japanese and Caribbean ...
10
Anti adult T cell leukemia/lymphoma effects of indole 3 carbinol
... HTLV-1-infected T-cell lines, HUT-102 [1], MT-4 [49] and TL-OmI [50], HTLV-1-uninfected T-cell line, Jurkat, MOLT-4 and CCRF-CEM, were cultured in RPMI 1640 medium supplemented with 10% ...
13
Impact of host immunity on HTLV 1 pathogenesis: potential of Tax targeted immunotherapy against ATL
... Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other ...
14
Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy
... B- cell NHL ...lineage leukemia-ALL xenografts, causing objective responses in all but one ...against T-lineage ALL ...induced leukemia progression in two chemore- sistant xenografts by up to ...
9
Clinical, hematological and cytogenetic profile in fibroblast growth factor receptor 1 rearranged hematoloymphoid malignancies
... eosinophilia, T-ALL and T-LBL with ZMYM2 gene being the most common fusion ...as T-cell Lymphoblastic lymphoma (T-LBL) and one as mixed phenotype acute leukemia ...The ...
8
Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti Tac Monoclonal antibody identifying the human receptor for T cell growth factor
... similar cell morphology and clinical ...(human T cell leukemia/lymphoma virus), a unique human type C retrovirus, whereas most patients with the Sézary syndrome do not have antibodies ...
9
Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions
... B cell antigen CD19 have been studied extensively for the treatment of B cell malignan- ...CAR T cell therapy, Kymriah, a CD19-directed CAR therapy for the treatment of relapsed/refractory B ...
21
Absence of FLT3 mutations in Iranian adult T-cell leukemia/lymphoma patients
... aggressive T- therapy regim small case ser fy that HTLV region, and A hough stem c for treatment, median survi comprehensio ATLL novel t Moreover, in human ca mechanisms m derstood, it h of DNA repai fore, ...
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