T cell mediated immunity
MHC ligand generation in T cell-mediated immunity and MHC multimer technologies for T cell detection
... We validated our method of in vivo labeling of phago- somal proteolytic activities on the mouse monocytic cell line J774, whose phagosomal protein content has been ex- tensively characterized (15). As shown by ...
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The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum – an epidemiological “natural experiment”
... clinical immunity is lost in absence of exposure to ...and T cell proliferation, allowing them to remain afebrile despite the persistence of low level ...more T cell intrinsic changes ...
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Coinhibitory receptor PD 1H preferentially suppresses CD4+ T cell–mediated immunity
... naive T cells is initiated by TCR engagement of spe- cific peptides that are presented by MHC ...of cell-surface coreceptors that are either costimulatory or ...on T cell surfaces can induce ...
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Impairment of Di(2 Ethylhexyl) Phthalate on Cellular Immunity in Kunming Mice
... suppress T cell-mediated immunity in ...days. T cell-mediated immunity assessed by phytohaemagglutinin (PHA) response was depressed in the DEHP treated mice com- ...
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H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection
... II-restricted T-cells are absolutely required for the control of experimental ...suppress T-cell- mediated ...human T-cells ...inhibits cell proliferation by interfering with the ...
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Toward a broadly protective influenza vaccine
... + T cell memory diminish the danger posed by these variant viruses? Pre-existing CD8 + T cell–mediated immunity directed at peptides from conserved internal proteins of the ...
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Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy
... antitumor immunity, where polymeric nanocarriers functionalized with lymphocyte-targeting ligands precisely delivered leukaemia-specific CAR genes into T cells ...host T cells, the surfaces of NPs ...
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α4β7 independent pathway for CD8+ T cell–mediated intestinal immunity to rotavirus
... and cell suspensions were made using a sterile cell strainer (40 µm) (Fisher Scientific, Springfield, New Jersey ...The cell suspensions were affinity purified through CD8 purification columns ...
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Rescue of CD8 T cell–mediated antimicrobial immunity with a nonspecific inflammatory stimulus
... memory T cell gener- ation from infused ...memory T cells, or to generate secondary effector T cells, but instead might function during the death phase of expanding CD8 CTLs and influence the ...
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Virus-stimulated neutrophils in the tumor microenvironment enhance T cell-mediated anti-tumor immunity
... Considering the contribution of the TME to the immune suppression anti-tumor response, successful immune therapy may be achieved by reconstructing the TME. We previously reported that the inactivated Sendai virus ...
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Cell mediated immunity in acute and chronic hepatitis
... circulating T lymphocytes which are capable of causing the destruction of Chang liver ...in T-cell function as measured by Con A-stimulated ...
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<p>Simultaneous Intramuscular And Intranasal Administration Of Chitosan Nanoparticles–Adjuvanted <em>Chlamydia</em> Vaccine Elicits Elevated Protective Responses In The Lung</p>
... both cell- mediated immunity and mucosal ...CD4 T-cells can play a signi fi cant role by decreasing the initial chlamydial load through neutralization and possible complement ...c ...
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Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity
... The effect of iron oxide nanoparticles on DTH reactions was firstly investigated by measuring the swelling of foot- pads in mice sensitized and challenged with ovalbumin. Ovalbumin challenge markedly increased the ...
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Peripheral Blood Lymphocyte Subset Counts in Pre-menopausal Women with Iron- Deficiency Anaemia
... and T lymphocyte counts in IDA ...mature T lymphocytes (CD4+ and CD8+) were observed in 40 IDA children by Attia et ...and cell-mediated immunity in children was also studied by Mullick ...
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The Immunodominant Influenza A Virus M158–66 Cytotoxic T Lymphocyte Epitope Exhibits Degenerate Class I Major Histocompatibility Complex Restriction in Humans
... same cell is coinfected (1). In addition to humoral immunity, cellular immunity against influenza involving both CD8 ⫹ and CD4 ⫹ T lymphocytes has been shown to be important ...is ...
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CD8⁺ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria
... immune mediated pathology associated with malaria are limited to the blood-stage of infection, with the preceding liver stage being asymptomatic ...protective immunity that depends on CD8 + T cells ...
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Nanovaccine for leishmaniasis: preparation of chitosan nanoparticles containing <em>Leishmania</em> superoxide dismutase and evaluation of its immunogenicity in BALB/c mice
... inducing cell-mediated immunity (T H 1 cells that is responsible for Leishmania eradication and could be indicated by IgG2a in mice) than control and other groups which received the soluble ...
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Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells
... NK cell–mediated killing of virus infected cells can contribute to elimination of viral infections ...NK cell–mediated attack of antiviral T cells can limit T cell ...
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CD4 T-Cell-Mediated Heterologous Immunity between Mycobacteria and Poxviruses
... CD4 T cells, but the small variations in responses between BCG-immune versus sham-immune mice seemed no different than the variations occurring within either of the ...by T cells infiltrating the visceral ...
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EVA LUATION OF THE ROLE OF CELL-MEDIATED IMMUNITY IN DERMATOPHYTOSIS
... of cell-mediated immunity, as manifested by delayed-hypersensitivity responses to trichophytin, in the resistance to dennatophytosis has been demonstrated by experimental infections; subjects with ...
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