Target Sites
Bioinformatic and Genetic Association Analysis of MicroRNA Target Sites in One Carbon Metabolism Genes
... miRNA target prediction methods and Monte-Carlo based statistical analyses, we identified two candidate miRNA ‘‘master regulators’’ (miR-22 and miR-125) and one candidate pair of ‘‘master co-regulators’’ ...
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A scoring matrix approach to detecting miRNA target sites
... miRNA target prediction systems have imple- mented post-processing steps in order to increase their ...of target sites. Here target sites that appear not to be conserved between mul- ...
9
Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding
... miRNA target sites (miRSNPs) can modify miRNA ...miRNA-binding sites in target genes are more ...miRNA target sites enhance or weaken the interaction between miRNA and its ...
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Ribozymes which cleave arenavirus RNAs: identification of susceptible target sites and inhibition by target site secondary structure.
... As well as demonstrating the effect of secondary structure on cis-acting ribozyme cleavage, we have shown trans activity of five ribozymes, all directed toward different target sites.. W[r] ...
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Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting
... Cell-based therapy exploits modified human cells to treat diseases but its targeted application in specific tissues, particularly those lying deep in the body where direct injection is not possible, has been problematic. ...
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CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites
... closed sites to induce de novo chromatin remodeling for cell fate ...on sites that have been “primed” for photorecep- tor rearrangement in the precursor ...Dependent sites show some level of ATAC ...
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Recognition of distinct target sites by a unique Labial/Extradenticle/Homothorax complex
... Examination of sequence of the EVIII enhancer failed to identify a consensus Lab/Exd/Hth-binding site. We thus considered that the Lab/Exd/Hth complex might recognise a divergent sequence, and searched for presence of a ...
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Is ZFP57 binding to H19/IGF2:IG-DMR affected in Silver-Russell syndrome?
... several target sites (ZTSs) and three demonstrated binding regions (BRs) for the imprinting factor ZFP57 in the H19/IGF2:IG-DMR suggest the involvement of this factor in the maintenance of methylation of ...
5
Spinal muscular atrophy treatment via targeting smn2 catalytic core
... effectively target sites in the SMN2 pre-mRNA, thereby modulating the splicing of SMN2 pre-mRNA to include exon 7 in the processed ...short target regions are 8-mers and 5-mers and also include the ...
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Site specific cleavage of genomic DNA mediated by triple helix formation
... This thesis describes the application of oligonucleotide directed triple helix formation to bind unique target sites in bacteriophage A, yeast, and human genomic DNA.. Cleavage at[r] ...
294
Comparison of DNA binding and integration half-site selection by avian myeloblastosis virus integrase.
... Alignment of 70 target site sequences 5' of the LTR half-site insertions with 68 target sites previously identified for the concerted insertion of both LTR termini LTR full-site reaction[r] ...
9
ONLINE AND OFFLINE TOOLS: CRISPR/CAS OFF TARGET DETECTION
... the target sites. Second, the off target effects are detected by the genome sequence ...off target sites are located on ...off target sites 33 ...
7
‘MicroRNA Targets’, a new AthaMap web-tool for genome-wide identification of miRNA targets in Arabidopsis thaliana
... miRNA163 target site search with target search parameters. All target genes and the position of the target sites in these genes are linked to a sequence display ...of target gene ...
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Resurvey of historical collection sites for Balston’s Pygmy Perch in the South West Linkages Target Area
... survey sites purely as a result of the low abudance that is typical of this ...such sites, and in catchments like the Dombakup Brook (part of the Warren River catchment) where the species was not captured, ...
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Characterization of the proneural gene regulatory network during mouse telencephalon development
... ing sites within 15 bp of each other ...Mash1 sites includ- ing the following TRANSFAC matrices: E12, E2A, Heb, Hen1, Hand1, E47, Ebox, myogenin, NeuroD, Myod, Areb6, Tal1, Lbp1, Ap4, E47, and ...Ngn2 ...
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RECENT ADVANCES AND MANAGEMENT APPRAISAL FOR THE CHEMOTHERAPY OF AIDS
... major barrier for curing HIV infection remains the ability of HIV to integrate in the host genome and remain latent. The thus-generated viral reservoirs cause viral rebound upon HAART interruption and impose lifelong ...
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Prevalence and Screening of Potential Fe(III) and Mn(VI) Resistant Microorganisms in Industrial Soil
... industrial sites are clay soil which is characterized by fine-grained soil and also the presence of Fe-oxides strongly affect a number of soil properties like color, surface adsorption of numerous ions and ...
9
The orienting of auditory attention: event related potential investigations
... The PI70 was found to be larger in response to the novel sounds than in response to the frequent and target tones. Tliis peak possibly results from the overlap of a P200 component elicited by all tones (Goodin et ...
450
Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action
... Insr mainly in liver and, to a lesser extent, in pancreatic β cells and in various brain regions (16). The majority (∼70%) of L1 mice are able to maintain normal glucose levels, but their circulating insulin levels are ...
10
Techniques for RNA in vivo imaging in plants
... The target sequence has to be accessible and not hidden by secondary ...the target has to be sufficient to open the hairpin, but the stem-loop has to be stable enough not to open in the absence of ...
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