TATA-Box Binding Protein
Severe and rapidly progressing cognitive phenotype in a SCA17-family with only marginally expanded CAG/CAA repeats in the TATA-box binding protein gene: A case report
... the TATA-box binding protein gene revealed a modest elongation of the CAG/CAA-repeat of only two repeats above the non-pathogenic threshold of 41, confirming a diagnosis of ...
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Concentrations of TATA box binding protein (TBP) type genes affect chordamesodermal gene expression
... ABSTRACT The TATA box-binding protein (TBP) is an essential component of transcription initiation complexes of all three eukaryotic RNA polymerases. Recent knockdown studies re- vealed that ...
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Penaeus monodon TATA Box-Binding Protein Interacts with the White Spot Syndrome Virus Transactivator IE1 and Promotes Its Transcriptional Activity
... immediate-early protein IE1 interacts with the Penaeus monodon TATA box-binding protein (PmTBP) and that this protein-protein interaction occurs in the absence of any ...
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TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes
... global binding profile of ...global binding profile of TRF3 is ...dependent protein catabolic process, histone modifica- tion, DNA replication and RNA processing, and stem cell population maintenance ...
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Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.
... Removal of this region did not significantly affect the binding to GST-TBP and GST-RB data not shown, and this domain by itself IE86ASN was unable to mediate binding to either protein in[r] ...
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Validation of reference genes for expression analysis by quantitative real time PCR in Leptinotarsa decemlineata (Say)
... ARF4; TATA box binding protein, TBP1 and TBP2; ribosomal protein RP4 and RP18; translation elongation factor 1α EF1α) from the transcriptome and validated the stability of their ...
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Human TATA Binding Protein Inhibits Human Papillomavirus Type 11 DNA Replication by Antagonizing E1-E2 Protein Complex Formation on the Viral Origin of Replication
... E2 binding site palindrome may be a determinant of DNA binding affinity ...DNA binding by BPV-1 and HPV-16 E2 are also affected by structures extending beyond the 12-bp E2 binding site palin- ...
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Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 protein.
... E2 binding sites, and BPV1 E2 was shown to strongly activate transcription of several BPV1 promoters but also to repress one promoter ...to binding to high-affinity sites. The repression is medi- ated by ...
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Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.
... or TBP were required for Top Strand 1 2 3 4 +10 +1- DISCUSSION Bottom Strand 5 6 7 8 --30 t i-I -20 C We have identified funcitonal domains of the IE86 protein of HCMV, which acts as a r[r] ...
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Relationship between TATA-binding protein and herpes simplex virus type 1 ICP4 DNA-binding sites in complex formation and repression of transcription.
... are protein-protein contacts between ICP4 and the DB complex on ...the binding of ICP4 to DNA is transmitted down the helix to the TATA box such that TBP binds with higher ...The ...
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Adeno-Associated Virus Major Rep78 Protein Disrupts Binding of TATA-Binding Protein to the p97 Promoter of Human Papillomavirus Type 16
... the binding of TATA-binding protein (TBP) to the TATA box of the p97 core promoter more significantly than it disrupted the preformed TBP-TATA ...the TATA ...
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Stabilized Binding of TBP to the TATA Box of Herpes Simplex Virus Type 1 Early (tk) and Late (gC) Promoters by TFIIA and ICP4
... the binding of TBP to the TATA box in the absence of a functional ...the binding of TFIID to the TATA box may differ and may require the presence of a functional INR ...the ...
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ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.
... Specifically, the simultaneous addition of ICP4, rTFIIB, and rTBP to a DNA template containing an ICP4 binding site and a TATA box resulted in a unique complex lower in electrophoretic m[r] ...
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Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus
... the TATA box, with an 8-bp consensus sequence TATA(A/T)A(A/T)(A/G) [34, ...inhibits TATA bind- ing by the C-terminal region of TBP on both pol III- [37] and pol II-dependent promoters ...the ...
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Overexpression of C/EBPβ Represses Human Papillomavirus Type 18 Upstream Regulatory Region Activity in HeLa Cells by Interfering with the Binding of TATA-Binding Protein
... TBP binding site strongly represses the HPV-18 ...abolishes binding of TBP to the URR TATA box ...the TATA box in the context of the URR would be expected to have the same ...
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Binding of ICP4, TATA-Binding Protein, and RNA Polymerase II to Herpes Simplex Virus Type 1 Immediate-Early, Early, and Late Promoters in Virus-Infected Cells
... the TATA box markedly reduced binding of ICP4, TBP, and polII to the promoter ...The binding of TBP to the DS1 region was also de- tected, but it was approximately 20% of that detected at the ...
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microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells
... in protein coding ...contain protein aggregates of TATA-binding protein ...the protein aggregates formed in such diseases also contain ...from protein aggregation to miRNA ...
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Baculovirus Infection Raises the Level of TATA-Binding Protein That Colocalizes with Viral DNA Replication Sites
... the protein extracts of TN-368 cells was also stained with the anti-IE2 antiserum ...TBP protein of about 36 kDa and the IE2 protein of 49 kDa. Protein size markers are given on the ...The ...
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PRH represses transcription in hematopoietic cells by at least two independent mechanisms
... homeodomain protein can regulate transcription in intact cells using this passive repression ...PRH binding sites up- stream of the target ...TK TATA box in ...from TATA box ...
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Expression of Human Herpesvirus 6B repwithin Infected Cells and Binding of Its Gene Product to the TATA-Binding Protein In Vitro and In Vivo
... REP protein was initially detected in the nucleus 24 h after infection and accumulated to high levels in the nucleus and was apparent in the cytoplasm within 72 h, but the REP protein was not detectable at ...
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