TBP, TATA binding protein
Inhibition of Host Transcription by Vesicular Stomatitis Virus Involves a Novel Mechanism That Is Independent of Phosphorylation of TATA-Binding Protein (TBP) or Association of TBP with TBP-Associated Factor Subunits
... of TBP in each of its three transcription factors can also be regulated by ...of TBP, depending on which sites are ...that TBP could be inactivated in VSV-infected cells by phosphorylation at an ...
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Baculovirus Infection Raises the Level of TATA-Binding Protein That Colocalizes with Viral DNA Replication Sites
... the protein extracts of TN-368 cells was also stained with the anti-IE2 antiserum ...the TBP protein of about 36 kDa and the IE2 protein of 49 ...kDa. Protein size markers are given on ...
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Multiple Functions of the Nonconserved N-Terminal Domain of Yeast TATA-Binding Protein
... of TBP and define a new TBP function: The muta- tions that confer dependence on the N-terminal domain lie in close proximity within the three-dimensional struc- ture of the TBP core domain (Figure ...
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Human TATA Binding Protein Inhibits Human Papillomavirus Type 11 DNA Replication by Antagonizing E1-E2 Protein Complex Formation on the Viral Origin of Replication
... E2 binding site palindrome may be a determinant of DNA binding affinity ...DNA binding by BPV-1 and HPV-16 E2 are also affected by structures extending beyond the 12-bp E2 binding site palin- ...
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Vaccinia Virus Intermediate and Late Promoter Elements Are Targeted by the TATA-Binding Protein
... of TBP and a dominant negative mutant on vaccinia virus intermediate and late promoter ac- ...of TBP in the cell were utilized to evaluate the importance of this protein in vaccinia virus ...of ...
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Overexpression of C/EBPβ Represses Human Papillomavirus Type 18 Upstream Regulatory Region Activity in HeLa Cells by Interfering with the Binding of TATA-Binding Protein
... EMSAs. Electrophoretic mobility shift assays (EMSAs) were performed in a total volume of 25 ml with nuclear extracts from HeLa and HepG2 cells, which were incubated in a reaction mixture containing 10 mM Tris-HCl (pH ...
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The Activation Domain of Herpesvirus Saimiri R Protein Interacts with the TATA-Binding Protein
... the binding of a multisubunit complex, TFIID, to the TATA element close to the transcription start ...is TBP, which is also required for transcription of RNA polymerase I and III ...of ...
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Genetic Interactions Between Nhp6 and Gcn5 With Mot1 and the Ccr4–Not Complex That Regulate Binding of TATA-Binding Protein in Saccharomyces cerevisiae
... with TBP (E isenmann et al. 1992). Spt3 is required for TBP recruitment to the GAL1 and PHO5 promoters in vivo (D udley et ...inhibits TBP binding to the HO promoter (Y u et ...Spt3 ...
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Recruitment of Tup1-Ssn6 by Yeast Hypoxic Genes and Chromatin-Independent Exclusion of TATA Binding Protein
... of TBP was observed under repressing conditions in the his- tone H4 mutant in the absence of the positioned ...chromatin-independent TBP exclusion was independently supported by studies with the tup1⌬98–304 ...
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The Saccharomyces cerevisiae SPT8 gene encodes a very acidic protein that is functionally related to SPT3 and TATA-binding protein.
... Since these phenotypes and others are also conferred by mutations in SPT3 and SPT15, this suggests that the SPT3, SPT8 and TBP proteins participate, directly or indirectly, at [r] ...
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Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus
... Ethanol tolerance is thought to be associated with mul- tiple genes that are widely distributed throughout the genome. Although significant efforts have been made to study ethanol tolerance in past decades, its ...
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Adeno-Associated Virus Major Rep78 Protein Disrupts Binding of TATA-Binding Protein to the p97 Promoter of Human Papillomavirus Type 16
... same TBP-16TATA complex pattern in ...of TBP or to the different ionic strengths of running buffer ...study. TBP-16TATA complex formation was reduced when Sp1 was added to the ...and TBP. It ...
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Binding of ICP4, TATA-Binding Protein, and RNA Polymerase II to Herpes Simplex Virus Type 1 Immediate-Early, Early, and Late Promoters in Virus-Infected Cells
... ICP4, TBP, and polII to promoters as a func- tion of ICP4 functional ...the binding of ICP4, TBP, and polII to promoters as a function of cis-acting sites within the ...the binding of polII to ...
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Stabilized Binding of TBP to the TATA Box of Herpes Simplex Virus Type 1 Early (tk) and Late (gC) Promoters by TFIIA and ICP4
... the binding of the general transcription factor TFIID, a multisubunit com- plex composed of the TATA binding protein (TBP) in associ- ation with 10 to 14 TBP-associated factors, ...
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In vitro examining the existing prognoses how TBP binds to TATA with SNP associated with human diseases
... The MBL2 gene, too, is characterized by a large de- parture of Δ from the in silico prediction. Mannose binding lectin (MBL) is a key protein in the develop- ment of the innate immune response. The polymor- ...
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Concentrations of TATA box binding protein (TBP) type genes affect chordamesodermal gene expression
... of TBP inhibits axis formation. (A) Both over-expression of TBP and high-dose injection of TBP-MO into the future marginal zone region of all blastomeres of the 4-cell embryo reduced expression of ...
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Boeing, Stefan (2008): Functions of Mediator and the RNA Polymerase II C-terminal Domain in Transcription Initiation. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... was not the case (Fig. 6B, lanes 12 and 13). For this reason the TFIIB/TFIIH-recruitment limiting mechanism may act downstream of functional TBP recruitment to the TATA- box. Another possibility is that the ...
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TBP-related factors: a paradigm of diversity in transcription initiation
... functional TBP paralogs in metazoans raises the question why more than one TATA binding fac- tor is required in these organisms while only one such protein is sufficient for proper execution ...
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Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.
... or TBP were required for Top Strand 1 2 3 4 +10 +1- DISCUSSION Bottom Strand 5 6 7 8 --30 t i-I -20 C We have identified funcitonal domains of the IE86 protein of HCMV, which acts as a r[r] ...
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Functional Interaction of CCR4-NOT Proteins With TATAA-Binding Protein (TBP) and Its Associated Factors in Yeast
... nonconsensus TATA sitivity of a ccr4 deletion or a caf1 deletion but did not elements, the not4 and not5 deletions allow increased suppress the glycerol temperature-sensitive phenotype transcription from all ...
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