Tissue-Specific Gene Expression
GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles.
... candidate gene is not feasible, a method is needed to decide which genes are worth investigating ...Computational gene prioritization presents itself as a solution to this problem, systematically analyzing ...
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The Relation of Codon Bias to Tissue-Specific Gene Expression in Arabidopsis thaliana
... that tissue-specific genes are the only genes that are adapted to the locally available pool of ...for expression in a given tissue is particularly important for the function of a coding sequence then ...
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The sulfate transporter family in wheat: tissue-specific gene expression in relation to nutrition
... of expression may be a reflection of tissue specific- ity, variation in development or nutritional status dependent upon any of these factors in combination with environmental ...a ...
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Lithium influences differentiation and tissue specific gene expression of mouse embryonic stem (ES) cells in vitro
... Our data show that by applying the EST in vitro screening system, a differen- tiation-inhibiting effect of LiCl would have been detected. High concentrations of LiCl inhibited cardiac and skeletal muscle differentiation ...
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A tissue-specific gene expression template portrays heart development and pathology
... a gene expression template (GET) containing only 56 genes could be used as a molecular signature to accurately specify at least 24 different disease-free tissues [12], including the ...maintaining ...
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Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome
... diverse expression biases all show an affinity toward autosomes [15]; therefore the apparent ‘ exodus ’ of male-biased genes from the X , previously considered as the major indirect evidence for MSCI in flies [1], ...
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Organ specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA
... how tissue-specific gene expression is achieved has largely relied on ChIP-seq to examine transcription factor occupancy at promoter regions, followed by enhancer analysis to look at the ...
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Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity
... higher expression of the tumor markers in the AMACR high expressing cells, which were identified by AMACR ...no expression of the basal cell marker p63 and higher expression of the luminal cell ...
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Embryonic stem cell differentiation: A chromatin perspective
... include tissue-specific genes that are silenced in all but the appropriate tissue, and X chromo- somes in female eutherian mammals, which can be either active or silenced for reasons of dosage ...for ...
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Molecular characterization, tissue expression and sequence variability of the barramundi (Lates calcarifer) myostatin gene
... MSTN gene has been cloned and characterized in a large number of high value commercial fish species such as atlantic salmon [9], shi drum [10], rainbow trout [11], gilthead sea bream [12], white bass [13], ...
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Localization of Wolbachia like gene transcripts and peptides in adult Onchocerca flexuosa worms indicates tissue specific expression
... employing specific anti-peptide antibodies was used to search for evidence of protein-level expression among our Wolbachia-like transcript ...and expression level (Table ...relevant expression ...
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Tissue specific regulation of CYP2B gene expression
... CYP2B expression and induction occurs in the enterocytes located on the villi but this protein is not expressed at all in the crypt cells (figure ...CYP2B expression and induction by PB shows similarities ...
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Prediction of the gene expression in normal lung tissue by the gene expression in blood
... of gene expression in human tissues is important for understanding the molecular mechanisms underlying tissue-specific control of gene ...using gene expression in blood ...
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ApoE knockout mice expressing human matrix metalloproteinase 1 in macrophages have less advanced atherosclerosis
... highly specific protease capable of degrading insoluble fibrillar collagens (16), especially of types I and III, which are the major collagens of the atherosclerotic plaque ...homologous gene to human MMP-1 ...
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An advanced reference genome of Trifolium subterraneum L. reveals genes related to agronomic performance
... confirmed gene expression for response to water deprivation, flavonoid biosynthesis and embryo development ending in seed dormancy, reflecting adaptation to the harsh Mediterranean ...of ...
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Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity and temperature, but not dissolved oxygen
... identified gene expression biomarkers in salmonid gill tissue that were specific to salinity and temperature treatments across multi- stressor conditions, smolt status and mortality using a ...
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Cytomegalovirus MicroRNA Expression Is Tissue Specific and Is Associated with Persistence
... were specific for the infected salivary ...of specific examples of differential isoform usage between the fibroblast and salivary gland ...that expression of the RCMV miRNA ...that expression ...
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Differential regulation of two histidine ammonia-lyase genes during Xenopus development implicates distinct functions during thyroid hormone-induced formation of adult stem cells
... earlier tissue- specific microarray analysis on the Xenopus laevis intestine revealed that the expression of mRNAs corre- sponding to a microarray cDNA probe (Probe ID# A_10_P010027, GenBank ...
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Organ-specific barcodes in human fetal development and stem cell differentiation : the pancreas in the spotlight
... [A] keyGenes was applied to human adult next-generation sequencing (nGs) and microarray datasets (test sets) using the fetal dataset as training set. (1) For nGs-derived count data, keyGenes searches for the best ...
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Regulation of Tissue-Specific Expression in the C. Elegans Embryo
... the expression of each gene in each cell population and the identity of the cells in each population, it should be possible to predict the expression of each gene in each ...high-resolution ...
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