Tissue-specific regulation
Tissue-specific regulation of pregnane X receptor in cancer development and therapy
... with tissue- specific, desirable ...differential tissue-specific expression of the protein, and its co-regulators may play a significant role in drug bioavailability in non-neoplastic versus ...
8
Tissue specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C elegans epidermal development
... and tissue-specific regulation of UNC-44/ankyrin ...that tissue and stage-specific expression of ankyrin isoforms relies on differential activity of positive and negative regulators of ...
10
Tissue specific regulation of CYP2B gene expression
... antibodies specific for three of the C/EBP proteins (a, p, and ô; Santa-Cruz Biotechnology) were used in gel supershift assays (figure ...C/EBP specific antibodies were added to the binding assay prior to ...
202
Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation
... Abstract Background: Appropriate epigenetic regulation of gene expression during lineage allocation and tissue differentiation is required for normal development. One example is genomic imprinting, which is ...
10
Tissue-Specific Regulation of Mouse Hepatocyte Nuclear Factor 4 Expression
... In addition, the reporter gene expression in intestinal tissue was considerably lower than that in liver and kidney tissues, and 1-Gal mRNA was also detected in brain tissue, in which HN[r] ...
9
Tissue-Specific Regulation of CD8+ T-Lymphocyte Immunodominance in Respiratory Syncytial Virus Infection
... DISCUSSION CD8 ⫹ T lymphocytes play an important role in clearance of virus and recovery from RSV infection in both humans and in the murine model. A striking feature of the CTL response to a protein antigen in mice is ...
10
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
... often tissue specific 10,11 making their interpretability in the context of PrCa risk ...with tissue-specific functional annotations have relied only on the GWAS significant variants (B100 in the most recent ...
13
Atlas of prostate cancer heritability in European and African American men pinpoints tissue specific regulation
... often tissue specific 10,11 making their interpretability in the context of PrCa risk ...with tissue-specific functional annotations have relied only on the GWAS significant variants (B100 in the most recent ...
14
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
... g Þ—the variance in trait explained by SNPs that reside within elements of a given functional category 12–15 . Here, we use targeted and genome-wide SNP array data from 59,089 male PrCa cases and controls of European ...
13
Differential and tissue specific regulation of the multiple rat c erbA messenger RNA species by thyroid hormone
... erbA,8-1 mRNA increase, whereas the levels of the pituitary- specific r-erbAf,-2 mRNA decrease with T3 treatment. In heart, kidney, liver, and brain the levels of r-erbAB-1 are unaf- fec[r] ...
6
Tissue-specific regulation of Na+ and K+ transporters explains genotypic differences in salinity stress tolerance in rice
... these pathways, and what role does K + retention play in salinity tolerance in rice? This study aimed to provide the answers to some of these questions and investigated the relative contribution of each of these ...
15
Differential Tissue-Specific Regulation of Antiviral CD8+ T-Cell Immune Responses during Chronic Viral Infection
... This possibility is unlikely, because we found no differences in TCR affinity between GP133-41- and NP396-406-specific CD8 ⫹ T-cell populations. A second question raised is as follows: why are ...
23
Regulation of Tissue-Specific Expression in the C. Elegans Embryo
... predictions with our current sample size are not yet high enough to make them broadly useful. We clustered this dataset, and found that many genes known to be expressed in particular tissues cluster together. Comparison ...
168
Tissue specific expression and regulation of the Mitogen Regulated Protein genes
... regulated in vivo, mrp3 promoter/lacZ constructs were analyzed in cell culture.. and in transgenic mice. of 3' sequences were sufficient to express detectable levels of p-galactosidase[r] ...
221
Identification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation
... of tissue-specific gene regulatory networks can yield insights into the molecular basis of a tissue’s development, function and ...CRX regulation in 5/5, 3/5 and 4/5 cases, respect- ...
13
Tissue-specific volatile-mediated defense regulation in maize leaves and roots
... (PPLS DA, n = 3-7) and (g) terpene volatiles emissions by maize roots exposed for four days to control plants (control, green) 260.. or to plants infested with six D.[r] ...
24
Nucleosome rotational setting is associated with transcriptional regulation in promoters of tissue specific human genes
... High-resolution maps indicate that individual nucleosomes tend to settle at approximately 10-bp inter- vals around an average position in the genome [4,6,8]. Histone cores, when forming a nucleosome with the DNA, thus ...
13
TISSUE-SPECIFIC STEM CELLS
... Unlike previous reports in which retinal stem cells were derived from the ciliary body as sphere colonies in the absence of FCS [19], the cells reported in this study were grown as monolayers of adherent cells obtained ...
12
TISSUE-SPECIFIC STEM CELLS
... human specific monoclonal antibodies (mAb; BD Biosciences, San Jose, CA, http://www.bdbiosciences.com, unless otherwise specified), fluorescein isothiocyanate (FITC) or PerCP-Cy5.5 anti-CD34 (8G12), ...
12
Tissue specific labeling in proteomics
... a specific cell type or tissue is straightforward, but no temporal information is obtained, and the sorting procedure itself can induce proteomic ...
15