Transcriptomics and Proteomics
From marine venoms to drugs: efficiently supported by a combination of transcriptomics and proteomics
... 6. Summary Venomous marine animals have been revealed to be an important resource for pharmacological tools with promising biological activities. These compounds not only have novel chemical structures but also new ...
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Transcriptomics and proteomics analysis to identify molecular mechanisms associated with meat quality traits
... und Proteomics-Analyse zur Identifizierung molekularer Mechanismen von Fleischqualitätsmerkmalen Ebergeruch und Wasserbindungsvermögen sind wichtige Qualitätskriterien des Schweinefleisches und beeinflussen sowohl ...
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Plant Aquaporins: Genome-Wide Identification, Transcriptomics, Proteomics, and Advanced Analytical Tools
... Rupesh K. Deshmukh † , Humira Sonah † and Richard R. Bélanger * Département de Phytologie–Faculté des Sciences de l’Agriculture et de l’Alimentation, Université Laval, Québec, QC, Canada Aquaporins (AQPs) are ...
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Comparative transcriptomics and proteomics of three different aphid species identifies core and diverse effector sets
... the proteomics and transcriptomics ...by proteomics we found that the ma- jority of corresponding transcript where more highly expressed in head versus body tissue (Additional file ...
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Comparative transcriptomics and proteomics of p-hydroxybenzoate producing Pseudomonas putida S12: novel responses and implications for strain improvement
... A transcriptomics and proteomics approach was employed to study the expression changes associated with p-hydroxybenzoate production by the engineered Pseudo- monas putida strain ...
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An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: Proteins associated with invasion and infection of the mammalian host
... Our integrated transcriptomics and proteomics analysis has provided an in-depth overview of protein secretion by the animal and human pathogen, F. hepatica that represents a significant step towards a ...
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Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells - a benchmarking study
... genomics, transcriptomics, and ...sion). Transcriptomics studies the RNA transcribed from a particular genome under various ...contrary, proteomics profiling requires utilization of larger numbers of ...
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Transcriptomics and proteomics of human skin Bastiaan J. H. Jansen and Joost Schalkwijk Date received (in revised form): 24th September 2002
... Bastiaan J. H. Jansen and Joost Schalkwijk Date received (in revised form): 24th September 2002 Abstract The epidermis protects the organism against physical, chemical and biological challenges, and it acts as a ...
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Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers
... * Present address: Marco Iannaccone, University of Naples Federico II, Naples, Italy; Witold E. Wolski, Systems Biology IT, SystemsX.ch, Zürich, Switzerland. M.M.E. and J.W. 3rd contributed equally to this article. ...
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Combining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD
... However, the system-level mechanism of BJF for the treatment of COPD is still unclear. The aim of this study was to gain insight into its system-level mechanisms by integrating transcriptomics, proteomics, ...
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Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis
... www.nature.com/scientificreports/ there is no curative therapy for OA; disease progression culminates in joint replacement surgery. OA is a complex disease, with both heritable and environmental factors contributing to ...
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The Influence of Preovulatory Estradiol on Uterine Transcriptomics and Proteomics Around Maternal Recognition of Pregnancy in Beef Cattle
... estradiol exposure, and 2) examine the effects of conceptus presence (interferon tau) on.. day 16 of pregnancy/estrous cycle. Specifically, we hypothesized that: 1) beef cows and heifer[r] ...
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Daptomycin resistance mechanisms in clinically derived Staphylococcus aureus strains assessed by a combined transcriptomics and proteomics approach
... Comparative proteomics of 616 versus 701 revealed a differential abundance of proteins in various functional categories, including cell wall-associated targets and biofilm formation ...
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Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice
... 6 h UP 0 5 10 15 20 25 30 35 0 5 10 15 20 25 30 35 Glycosylation Insulin Signaling Pathway Mitochondrial Energy Metabolism Skeletal Muscle: Myogenesis & Myopathy Huntington's Diseas[r] ...
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Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia
... hypothesized that the developmental arrest, sustained pro- liferation, and prosurvival characteristics of AML blasts may in part be mediated through misexpression or mislocalization of proteins to the nucleus. The aim ...
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Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease
... Proteostasis Therapeutics Inc. provided funding support for JG, BG and KAL and for the three-stage Mass Spectrometry Tandem Mass Tag Proteomics study, which was performed by the Gygi Lab, Department of Cell ...
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Combination of label-free quantitative proteomics and transcriptomics reveals intraspecific venom variation between the two strains of Tetrastichus brontispae, a parasitoid of two invasive beetles
... for proteomics analyses, which is invaluable, particularly in the absence of a sequenced ...spectrometry-based proteomics method, which enables the identification and quantification of low-abundance ...
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Proteomics and transcriptomics of broccoli subjected to exogenously supplied and transgenic senescence-induced cytokinin for amelioration of postharvest yellowing
... used proteomics and transcriptomics to compare the mechanisms of ipt-transgenic and N 6 -benzylaminopurine (BA) CK treatment of broccoli during postharvest ...
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Tricks to translating TB transcriptomics
... To fully utilize the information from high-throughput OMICS approaches, there is the need to develop a platform for data integration. This should systematically capture all information from transcriptomics, ...
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Proteomics Informed by Transcriptomics for Characterising Active Transposable Elements and Genome Annotation in Aedes Aegypti
... Identification of proteins derived from mobile genetic elements using PIT. (A) 1047[r] ...
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