transient receptor potential cation channel
<p>Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling</p>
... Transient receptor potential cation channel protein 6 (TRPC6) is colocalized in the kidney podocyte glomerular slit diaphragm with the protein, ...TRPC6 channel is induced by ...
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Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
... Here we provide evidence for a critical role of the transient receptor potential cation channel, subfamily V, member 4 (TRPV4) in normal bladder function. Immunofluorescence ...
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Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma
... TRPV1 receptor is expressed on the peripheral terminals of airway specific, vagal afferent nerves [38] and it has been suggested that the LAR [23] and AHR [30, 39] are reflex ...ion channel on sensory ...
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The role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies
... A recently published comprehensive review article summarizes menthol’s biological activities, including its cooling effect and its analgesic, antifungal, antibacterial, antipruritic, anticarcinogenic, anti-inflammatory, ...
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Schäfer, Sebastian (2019): Pharmakologische Beeinflussbarkeit der TRPM7 Kanalkinase. Dissertation, LMU München: Medizinische Fakultät
... Das Gen human transient receptor potential cation channel, subfamily M, member 7 (TRPM7) ist auf dem Chromosom 15q21.2 lokalisiert. Es besteht aus 39 Exons und kodiert ein Protein von ...
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How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways
... activate transient receptor potential cation channel, subfamily A, member 1 (TRPA1) receptors in air- way sensory neurons, resulting in neurogenic inflammation and respiratory ...
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Cigarette smoke–induced neurogenic inflammation is mediated by α,β unsaturated aldehydes and the TRPA1 receptor in rodents
... the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) (3, 4), TRPV1 does not mediate the neuronal action of CS, because the selective TRPV1 receptor ...
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A temporal examination of calcium signaling in cancer- from tumorigenesis, to immune evasion, and metastasis
... on transient receptor potential cation channel subfamily A member 1 (TRPA1) and secreted protein acidic and rich in cysteine (SPARC) point to areas in need of further ...
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In vitro pharmacological characterization of a novel TRPA1 antagonist and proof of mechanism in a human dental pulp model
... selective transient receptor potential cation channel, member A1 (TRPA1) antagonist identified during a focused drug discovery ...TRPA1 channel heterologously expressed in human ...
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Original Article Effect of cold and hot compress on neutrophilic migration to the site of doxorubicin extravasation
... C5a receptor (CD88), interleukin-8 receptor (IL-8RA), and transient receptor potential cation channel subfamily V member 1 (TRPV1) were also ...
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Ocular transient receptor potential channel function in health and disease
... With the realization in the last decade of the polymodal regulatory roles of TRP channels, there is heightening interest in studying how they elicit such control. This is evident based on the ever-increasing number of ...
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Polymodal roles of transient receptor potential channels in the control of ocular function
... mediating receptor control of numerous life-sustaining responses. Transient receptor potential (TRP) channels signal transduce a wide variety of different sensory stimuli to induce responses ...
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Autoantibody against transient receptor potential M1 cation channels of retinal ON bipolar cells in paraneoplastic vitelliform retinopathy
... a cation chan- nel named transient receptor potential M1 (TRPM1, also known as melastatin ...TRPM1 cation channel is essential for ON bipolar cell signaling ...
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OConor_unc_0153D_14695.pdf
... Transient Receptor Potential (TRP) cation channels serve as polymodal sensors in mammalian cells and come in six subtypes: TRPC (“canonical”), TRPV (“vanilloid”), TRPM (melastatin”), TRPP ...
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Transient receptor potential (TRP) gene superfamily encoding cation channels
... In the retina, microglial cells are needed for neuronal homeostasis and provide innate immune defence. Exposure of microglia to chronic stress is associated with various neurodegenerative diseases, including retinal ...
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TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNEL: AN EMERGING TARGET FOR PAIN
... TRP channel comprises six putative transmembrane domains (vertical rectangles in the figure) and a cation-permeable pore (was indicated by ‘P’ between transmembrane domain 5 and transmembrane domain ...TRP ...
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Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture responding channel”
... The transient receptor potential vanilloid receptors 1 and 4 (TRPV1 and TRPV4) and the acid-sensing ion channel 3 (ASIC3) are mechanosensi- tive channels related to local ATP release in ...
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The role of the transient receptor potential ankyrin type-1 (TRPA1) channel in migraine pain: evaluation in an animal model
... that target these mediators for migraine treatment. Tran- sient receptor potential (TRP) channels are a large family of non-selective cation channels that are important in pain signaling pathways. ...
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Mechanism and therapeutic effectiveness of nerve growth factor in osteoarthritis pain
... Abstract: Osteoarthritis (OA) is the most common form of articular joint arthritis and a cause of significant morbidity. In this review, we present the role of nerve growth factor (NGF) in pain generation, relationship ...
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Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells
... and in prostate cancer cell lines. We here investigated the role of TRPM4 in prostate cancer cells that - in contrast to hPEC - are characterized by several pathophysiological changes in cellular functions such as ...
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