tumor cell-associated exosome
APC activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production
... positively associated with lymph node and/or distant metastasis, a more advanced clinical stage, as well as a poor prognosis for patients with ...CRC cell growth, metastasis, and tumor angiogenesis ...
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<p>The Exosome And Breast Cancer Cell Plasticity</p>
... the tumor-nourishing com- partment in the tumor microenvironment responsible for the process of carcinogenesis and ...of tumor cells are ...cancer cell survival and growth, which also promotes ...
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Proteomic analysis of exosomes derived from human lymphoma cells
... in cell culture supernatants as well as in the serum: a soluble form of ICAM-1 (sICAM-1) and a membranous form of ICAM-1 (mICAM-1) associated with ...of cell surface ICAM-1 and could bind to ...
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Distinct Origin of Claudin7 in Early Tumor Endosomes Affects Exosome Assembly
... cancer-initiating cell microvesicles (CIC-TEX) reprogram Non-CIC towards fortified ...and associated signaling molecule recruitment; non-palmitoylated claudin7 supports recruitment of trafficking ...
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Exosome-mediated communication in the tumor microenvironment contributes to hepatocellular carcinoma development and progression
... Additionally, tumor cell-derived exo- somes containing functional proteins and miRNAs can affect the biological fate of endothelial ...firmly associated with the de- gree of lumen formation [74]. ...
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Tumor exosome-mediated promotion of adhesion to mesothelial cells in gastric cancer cells
... We were unable to identify specific TEX-induced gene expression alterations by PCR array of metastasis- related gene targets; changes in expression at 24 and 48 hours after TEX internalization completely differed from ...
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M1-like tumor-associated macrophages activated by exosome-transferred THBS1 promote malignant migration in oral squamous cell carcinoma
... The collected CM were filtered through 0.10 μm Filter Units, then transferred to Amicon® Ultra-15 centrifugal filter device (100 K, Merck Millipore, USA) and concen- trated by centrifugation at 3900 rpm at 4 °C for 15 ...
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Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6
... Fluorescence-activated cell sorting; FBS: Fetal bovine serum; GA: Gestational age; GFAP: Glial fibrillary acidic protein; H&E: Hematoxylin and eosin; HDF: Human dermal fibroblast; hUC: Human umbilical cord; ...
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Exosomes derived from cancerous and non-cancerous cells regulate the anti-tumor response in the tumor microenvironment
... DC cell, dendritic cell; EpCAM, epithelial cell adhesion protein; ECM, extracellular matrix; EGFRvIII, epidermal growth factor receptor; Egr-1, early growth response-1; EMT, epithelial mesenchymal ...
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Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells
... biochemical, cell biological, and high- resolution fluorescence and electron microscope imaging ...and tumor-associated vascular endothelium, which is believed to facilitate vascular and tissue ...
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Exosome mediated transfer of miR 222 is sufficient to increase tumor malignancy in melanoma
... possibly associated with ...the cell cycle rate possibly modulated as a consequence of EXO/miR-222 ...stimulation cell cycle evaluation showed either in control or in EXO/Tween treated: 75–78 % of ...
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Exosomal cell-to-cell transmission of alpha synuclein oligomers
... [77,78]. Exosome secretion can therefore be used by cells, including neu- rons and astrocytes, to clear molecules originally des- tined for lysosomal degradation ...from cell to cell ...that ...
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Tumor heterogeneity as a rationale for a multi-epitope approach in an autologous renal cell cancer tumor vaccine
... by immunohistochemistry with special emphasis on patient outcome. In all, 48% of the tumors were positive for NSE and tumors with an immune-positivity for NSE had a shorter (but insignificant) RCC-specific survival. In ...
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Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
... colorectal tumor found LoH in the HLA-C *08:02 region of tumor cells, which is required for KRAS G12D neoantigen presentation ...was associated with better survival among advanced cancer patients ...
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Combined aberrant expression of E-cadherin and S100A4, but not β-catenin is associated with disease-free survival and overall survival in colorectal cancer patients
... Each tumor was re-evaluated by analysis of the medical records and the tissue slide files by one ...pathologist. Tumor location (right side or left side), the degree of differentiation (well, moderately, ...
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Progression and prognostic value of ECT2 in non-small-cell lung cancer and its correlation with PCNA
... to tumor cell differentiation degree, TNM stage, lymph node metastasis, and prognosis in non-small-cell lung cancer ...proliferating cell nuclear antigen (PCNA) levels in ...was ...
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Review Article Enchondromatosis: insights on the different subtypes
... phleboliths, associated with soft tissue calcifications in ...Spindle cell haeman- gioendothelioma is more specific for Maffucci syndrome ...angiosarcoma associated with Maffucci syndrome ...mors ...
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Tumor associated tissue eosinophilia a prognostic marker in malignant tumors
... 1 tumor whereas 5 cases (25%) exhibited a high blood ...1 tumor was 740 cells/ cu mm and it was 510, 890 and 830 cells/ cu mm in tumor grade 2, 3 and 4 ...of tumor spread at periphery ...
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The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
... resistance associated gene and Bif-1, which are components of the Beclin1/class III PI3K complex, also participate in controlling cell proliferation and suppressing tumorigenesis ...Paneth cell ...
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Exosome-mediated delivery of MALAT1 induces cell proliferation in breast cancer
... containing exosome-depleted FBS (prepared by overnight ultracentrifugation at 100,000 × g at 4 ° C) for 48 ...tioned cell culture media were collected and centrifuged at 300 × g for 5 minutes, 2,000 × g for ...
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