Tumor response
Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemo- radiation therapy
... and tumor response to ...residual tumor cells while false negatives can cause patients who have obtained complete pathologic responses to receive unnecessary ...treatment response in clinics, ...
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Multimodality Imaging of Tumor Response to Doxil
... of tumor response to Doxil. Tumor samples treated with 2 doses of Doxil (10 mg/kg) or PBS were harvested for histological ...UM-SCC-22B tumor cells after Doxil treatment as assessed by Ki-67 ...
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Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib
... the tumor response to sunitinib in two consecutive patients with pretreated, progressive, meta- static extraskeletal myxoid chondrosarcoma, carrying the EWSR1-CHN ...the response was evident after ...
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Integrin αvβ3-Targeted Radiotracer 99mTc-3P-RGD2 Useful for Noninvasive Monitoring of Breast Tumor Response to Antiangiogenic Linifanib Therapy but not Anti-Integrin αvβ3 RGD2 Therapy
... in tumor progression [3, 5]. Targeting tumor angiogenesis with small molecu- lar inhibitors represents a promising strategy for con- trolling and eradicating tumor growth ...pre-clinical tumor ...
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Recommendations for imaging tumor response in neurofibromatosis clinical trials
... Children’s Tumor Founda- tion, as a senior advisor to the Neurofibromatosis Therapeutic Acceleration Program, and as a member of the board of scientific counselors to the ...s Tumor Foundation, Department ...
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Tumor Response to Temsirolimus for Epithelioid Angiomyolipoma and Novel Mutation of SMARCB1/INI1 Tumor Suppressor Gene
... A 58-year-old man was referred to medical oncology clinic at Samsung Medical Center with multiple intra- abdominal masses. He had been diagnosed with malignant monotypic epithelioid angiomyolipoma that had formed left ...
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Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy
... of tumor response but also represents the major obstacle for a more meaningful impact on long- term survival in genotype-matched precision medicine ...remarkable tumor regression [20], leading to ...
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Thesis
... measuring tumor response to therapy is very important in determining the course of care of a ...about tumor biology, clinicians are unable to determine the exact cocktail of therapies that will ...
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Perspectives and Prospects in the Chemotherapy of Gastrointestinal Cancer
... With increased toxicity a plateau was reached beyond which no significant further regression of tumor could be obtained, and sur- vival, despite tumor response, wa[r] ...
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Brain Tumor Detection using Modified Fuzzy Segmentation
... monitor tumor response to treatment ...brain tumor from the magnetic resonance images is important in medical diagnosis because it provides information associated to anatomical structures as well as ...
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Mathematical Model Solid Tumor At The Stage Of Angiogenesis With Immune Response
... avascular tumor can sometimes become dormant and there is an indefinite period for which growth stops (Folkman, ...The tumor can overcome this deficiency by acquiring a blood supply and it does so by ...
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Osteosarcoma: Current status of immunotherapy and future trends (Review)
... bone tumor and represents a major therapeutic challenge in medical ...performed. Tumor-infiltrating lymphocytes and some tumor antigens have been identified in osteosarcoma and resulted in an ...
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Dose-effect relationship of CpG oligodeoxyribonucleotide 1826 in murine Lewis lung cancer treated with irradiation
... tumoral response to fractionated IR. Enhancement of the treatment response was evident in the longer delay in tumor growth, an improved sensitization enhancement ratio, and a higher rate of apoptosis ...
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Targeting microenvironment in cancer therapeutics
... of tumor cells and the activation of Sma and Mad (SMAD) and mitogen-activated protein kinase (MAPK) signaling pathways, which all can contribute to the induction of EMT ...in tumor invasion [15, ...
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A Therapeutic Approach To Cancer Gene Therapy
... destroy tumor cells, for example, the loss of tumor suppressor genes ...a tumor suppressor gene such as P53 by inserting a copy of the wild-type gene; in fact, insertion of the wild-type P53 gene ...
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Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
... subsequent tumor challenge ...CTL response in tumor-bearing mice, although this response is incapable of controlling tumor growth (Figure 2 and Figure 3), and further cos- timulation by ...
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Modelling tumor growth with immune response and drug using ordinary differential equations
... modelling tumor growth is a vast study by researchers, with each focussing on different aspects on cancer development ...fighting tumor that has been summarized by Adam and Bellomo ...(CTL) response ...
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Targeting microRNAs as key modulators of tumor immune response
... of tumor suppressor miRNA level is obtained by the delivery of chemically synthesized short double-stranded oligonucleotides, which functionally mimic pre-miRNA duplexes ...and tumor-mediated immunity, ...
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Li, Huihui (2017): Role of the p53/miR-34a pathway in the response to tumor hypoxia. Dissertation, LMU München: Medizinische Fakultät
... In tumor cells, EMT transcription factors (EMT-TFs) may primarily redefine the epithelial status of the cell, potentially - but not necessarily - assigning stem cell (SC) characteristics to dedifferentiated ...
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Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance
... this response (Figure ...Myc-induced tumor- igenesis, such as the Eμ-myc transgenic mouse, which is predisposed to develop B-cell tumors with high pene- trance ...
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