two-compartment model
Detection of nanolevel drug metabolites in an organotypic culture of primary human hepatocytes and porcine hepatocytes with special reference to a two-compartment model
... cellular model of primary human hepatocytes to investigate and quantify the parent drug, as well as drug metabolites inside human hepatocytes and outside human hepatocytes to evaluate the quantity of drug ...
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Surfactant disaturated-phosphatidylcholine kinetics in acute respiratory distress syndrome by stable isotopes and a two compartment model
... the two compartment model reported in figure 1. This model is physiologically plausible, but too complex to be uniquely resolvable from the available data, since only the mass in the alveolar ...
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Fitting the two-compartment model in DCE-MRI by linear inversion
... The effect of LLS on accuracy and precision is more ambiguous. Key observations are summarised in Figure 6. As a general rule, the LLS is preferred at low-noise conditions and the NLLS at high temporal resolution. In the ...
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<p>Population pharmacokinetic analysis of tramadol and <em>O</em>-desmethyltramadol with genetic polymorphism of <em>CYP2D6</em></p>
... one- compartment and a two-compartment model to the plasma concentrations of tramadol, to develop a basic population PK model for ...
11
Cfd Simulation Of Mixing Effect On A Continuous Stirred Tank Reactor
... a two compartment model for particle size distribution in polymerization reactors by taking into account the variations in turbulent kinetic energy and its dissipation rate in the vessel, using k-ε ...
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Metabolism of rumen infused skatole and effects on hepatic gene expression in sheep : a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in Animal Science at Massey University, Palmerston North, New Zealand
... A two-compartment model fitted to the rumen liquid phase (compartment 1 ) and plasma (compartment 2) skatole data of rumen skatole-infused ...The model provides an estimated rate ...
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Dynamic Contrast Enhanced MRI of Mouse Liver: A Feasibility Study Using a Dual Input Two Compartment Tracer Kinetic Model
... dual-input two-compartment model to liver tissue concentration-time curve and the impulse residual function R t ( ) that is the result of the fitting of the enhancement ...
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17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia
... a two-compartment model showing important differences when del(17p) CLL patients were compared with non-del(17p) patients treated with rituximab and chemotherapy: (1) clearance of rituximab was ...
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Comparison of oral absorption models for pregabalin: usefulness of transit compartment model
... A two-compartment model with first-order elimination and proportional residual error was chosen as the basic PK ...central compartment volume incorporated into the basic model was ...
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Forest Fires Model and SIR Model Used in Spread of Ebola Virus in Prediction and Prevention
... mathematical model for health care workers and researchers to help in the fight against the Ebola ...SIR model, the most classic model in infectious disease, and published data, we realize the ...
10
Li Fraumeni syndrome, cancer and senescence: a new hypothesis
... “two compartment” model shows that activated stromal fibroblasts respond to the oxidative stress generated by tumours by becoming autophagic and switching metabolism to aerobic glycolysis, which ...
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Markov chain Monte Carlo analysis of cholera epidemic
... matical model for the dynamics of cholera with control measures such as educational campaign- s, vaccination, sanitation, and treatment as control strategies in limiting disease are explained in ...mathematical ...
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A THREE COMPARTMENT MODEL DESCRIBING TEMPERATURE CHANGES IN TETHERED FLYING BLOWFLIES
... three-compartment model for the fly body, assuming the following: (1) heat production in the thorax is due to flight muscle activity; (2) heat is lost to the surroundings from three compartments, the head, ...
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ANPR using the Template Matching technique in MATLAB
... product model. The product model which utilizes picture preparing tool compartment for chain of picture handling systems which are executed in ...
5
Pharmacokinetics of single- and multiple-dose roflumilast: an open-label, three-way crossover study in healthy Chinese volunteers
... In addition, pharmacokinetic analyses were performed by compartmental analysis using WinNonlin version 6.3. Nonlinear least squares regression analysis was performed using the plasma roflumilast and roflumilast N-oxide ...
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EVALUATION OF THE DYNAMIC CHARACTERISTICS OF PASSENGER COMPARTMENT CAR MODEL 61-779
... Для оценки динамических качеств новых рельсовых экипажей на стадии проектирования , как правило , выполняют расчеты по определе - нию основных динамических показателей в сравнении с но[r] ...
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Compartment Mixing Model in a Stirred Tank Equipped Dual Rushton Turbine
... ith compartment. This system of first-order differential equations was solved by Runge- Kutta fourth order method. The initial values are computed with the knowledge of the volume and concentration of the tracer ...
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Feasibility of ultrasound measurement in a human model of acute compartment syndrome
... clinically compartment syn- drome usually occurs due to cellular ...the compartment during measurement may have resulted in underestimation of ...the compartment and in cases of fractured tibia were ...
7
Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times faster
... reduced model is used as a proxy for ...neuron model, with its quick run-time, to explore new hypothesises and parameter ...reduced model can produce the same behaviour in the full ...full ...
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An open source software for analysis of dynamic contrast enhanced magnetic resonance images: UMMPerfusion revisited
... perfusion model of choice (see Fig. 2a). For each perfusion model a panel showing the inputs is visu- alized when selected from the top down menu ...the model was mostly kept the ...the model ...
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