U1 snRNP
Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
... the U1-70k ...the U1 snRNP proteins, we were interested in determining the CMV-anti- body status of patients with autoimmune disease who have antibodies to ...
6
ALS-causative mutations in FUS/TLS confer gain- and loss-of-function by altered association with SMN and U1-snRNP
... Since the altered association of FUS/TLS mutants with SMN and U1-snRNP could perturb splicing, we next tested if the ALS-linked mutations in FUS/TLS affected alternative splicing. After inducing expression ...
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A Genetic Screen for Pre-mRNA Splicing Mutants of Arabidopsis thaliana Identifies Putative U1 snRNP Components RBM25 and PRP39a
... U5 snRNP protein PRP8, a large, con- served protein at the catalytic core of the spliceosome; RTF2, a novel protein that may be involved in ubiquitin-based reg- ulation of splicing (Sasaki et ...of snRNP ...
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Activity of the Human Papillomavirus Type 16 Late Negative Regulatory Element Is Partly due to Four Weak Consensus 5′ Splice Sites That Bind a U1 snRNP-Like Complex
... of U1 snRNP, U1A ...and U1 snRNA (Fig. 5E), but not U1 70K ...the U1 70K ...tion-PCR-amplified U1 snRNA affinity purified on NRE ...affinity-purified U1 snRNA cDNA; lane ...
11
Human parvovirus B19 nonstructural protein NS1 enhanced the expression of cleavage of 70 kDa U1-snRNP autoantigen
... Sm, U1-snRNP, SSA, SSB, Scl-70, Jo-1, Ku, ...Sm, U1-snRNP, Ku, SSA, SSB and Jo-1 was detected in COS-7 cells trans- fected with pEGFP, pEGFP-NS1 and pEGFP-NS1K334E, whereas no expression of ...
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trans and cis Splicing in Trypanosomatids: Mechanism, Factors, and Regulation
... In cis splicing, factors involved in capping, splicing, and polyadenylation interact with the carboxy-terminal domain of RNA polymerase II at an early stage of mRNA production, and these processes are therefore coupled ...
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Genetic Suppression of Intronic +1G Mutations by Compensatory U1 snRNA Changes in Caenorhabditis elegans
... a U1 type splice junction even though this splicing defines snRNA gene, 1 of 12 in the ...this U1 snRNA gene from splicing at the mutant splice ...a U1 snRNA gene: sup-6 maps to position nucleotide ...
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The Drosophila U1-70K Protein Is Required for Viability, but Its Arginine-Rich Domain Is Dispensable
... Drosophila U1-70K protein is U1 snRNP specific: tide repeats, have no mutant ...the U1-70K RS deletion allele is com- are clearly orthologous to each of the human U1 snRNP- bined ...
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Distance-Dependent Processing of Adeno-Associated Virus Type 5 RNA Is Controlled by 5′ Exon Definition
... the U1 snRNP and the putative TIA-1 binding site and the mutation introduced into P7J700CapDT30CAA are illustrated in panel ...the U1 snRNP has an inhibitory effect on polyadenylation at ...
11
Tra2-Mediated Recognition of HIV-1 5′ Splice Site D3 as a Key Factor in the Processing of vpr mRNA
... the U1 snRNP is ...the U1 snRNP to the 5=ss promotes interactions across the exon and thereby activation of the upstream 3=ss ...the U1 snRNA, we demonstrated that the splicing enhancer ...
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Inclusion of the Central Exon of Parvovirus B19 Precursor mRNA Is Determined by Multiple Splicing Enhancers in both the Exon and the Downstream Intron
... of U1 snRNP to the D2 donor site and that the SR proteins that bind to ESE1 and ESE2 help splicing at the A1-1 and A1-2 acceptor sites, respectively, de- ...
6
Autoantibodies specific for apoptotic U1 70K are superior serological markers for mixed connective tissue disease
... anti- U1 snRNP autoantibodies by counter-immunoelectro- phoresis, and for antibodies against one or more compo- nents of the U1 snRNP complex by ...by U1 snRNA ...
8
01 G3 U1 34 53 F
... Think of a strategy to help you solve the problem.. How did you make an organized list to solve a problem? Use words, pictures, or numbers to explain.. Choose one of the[r] ...
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Wetting front dynamics in isotropic porous media
... An implicit assumption we made above, namely that in the wetting mode the contact-line speed u1 equals to the cross-sectionally averaged flow velocity u1,f low associated with the motion[r] ...
11
The Existence of Noise Terms for Systems of Partial Differential and Integral Equations with (HPM) Method
... It was formally shown that by canceling the noise terms that appear in u0 and u1 from u0, even though u1 contains further terms, the remaining noncancelled terms of u0 may give the exact[r] ...
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MPM1D U1 EQAO Booklet 2014.doc
... Open Response Grade 9 Assessment of Mathematics, Relations Practice.. 8..[r] ...
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01 G3 U1 04 33 F
... Colour all the odd numbers. Colour the diagonal where the ones digit and the tens digit are the same in each number... How can you find the diagonal where the digits in each number ad[r] ...
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A splicing enhancer in the 3'-terminal c-H-ras exon influences mRNA abundance and transforming activity.
... with U1 small nuclear RNA (snRNA) ...of U1 RNAs with compensatory base changes (9, 11), and this approach was used here to verify that the failure to splice the miniexon or the miniexon with the backward ...
11
RNA Recognition Motif (RRM) of La/SSB: The Bridge for Interparticle Spreading of Autoimmune Response to U1-RNP
... Our experimental data strongly rein- force the hypothetical model proposed some years ago by Monneaux and Muller (9,25). In this model, the RRM consensus sequence can drive epitope spreading in spliceosomal proteins via ...
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Suppressor U1 snRNAs in Drosophila.
... from the immunoprecipitated U1 snRNPswere analyzed by the 3G and 9G primer extension assays, it was o h served that all six suppressor mutations were present in U1 snRNPs[r] ...
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